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1.
Ann Chir Plast Esthet ; 69(1): 85-91, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-37032218

RESUMEN

Facial gunshots injuries remain challenging and present functional and aesthetic problems. Such defects generally require composite tissue flaps for reconstruction. Rebuilding the palate and the maxilla is especially delicate because it requires reconstitution of the facial buttresses, and replacement of bony hard palate, based on occlusion, as well as the restoration of the thin intraoral and intranasal lining which normally constitute the soft palate. Various methods of reconstruction have been applied to this area in search of an ideal soft tissue and bone flap to restore the bony framework of the maxilla and palate while providing an internal lining. The scapula dorsal perforator flap is used in the case of a patient to successfully reconstruct the palate, the maxilla and the nasal pyramid in one stage. Free tissue transfer using thoracodorsal perforator flaps and scapula bone free flap have been already described in literature but never to perform the nasal pyramid reconstruction at the same time. Good functional and aesthetic results have been obtained in this case. This article also reviews, through the authors experience and literature, anatomical landmarks, indications, technical surgical tricks, advantages and disadvantages of this flap for palatal, maxillary and nose reconstruction.


Asunto(s)
Traumatismos Faciales , Colgajo Perforante , Procedimientos de Cirugía Plástica , Rinoplastia , Humanos , Maxilar/cirugía , Colgajo Perforante/cirugía , Rinoplastia/métodos , Nariz/cirugía , Traumatismos Faciales/cirugía
2.
Cleft Palate Craniofac J ; 59(3): 336-346, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33823625

RESUMEN

INTRODUCTION: Since the early stages of alveolar bone grafting development, multiple types of materials have been used. Iliac cancellous bone graft (ICBG) remains the gold standard. DESIGN/METHODS: A review of literature is conducted in order to describe the different bone filling possibilities, autologous or not, and to assess their effectiveness compared to ICBG. This review focused on studies reporting volumetric assessment of the alveolar cleft graft result (by computed tomography scan or cone beam computed tomography). RESULTS: Grafting materials fall into 3 types: autologous bone grafts, ICBG supplementary material, and bone substitutes. Among autologous materials, no study showed the superiority of any other bone origin over iliac cancellous bone. Yet ICBG gives inconsistent results and presents donor site morbidity. Concerning supplementary material, only 3 studies could show a benefit of adding platelet-rich fibrin (1 study) or platelet-rich plasma (2 studies) to ICBG, which remains controversial in most studies. There is a lack of 3-dimensional (3D) assessment in most articles concerning the use of scaffolds. Only one study showed graft improvement when adding acellular dermal matrix to ICBG. Looking at bone substitutes highlights failures among bioceramics alone, side-effects with bone morphogenetic protein-2 composite materials, and difficulties in cell therapy setup. Studies assessing cell therapy-based substitutes show comparable efficacy with ICBG but remain too few. CONCLUSION: This review highlights the lack of 3D assessments in the alveolar bone graft materials field. Nothing dethroned ICBG from its position as the gold standard treatment at this time.


Asunto(s)
Injerto de Hueso Alveolar , Sustitutos de Huesos , Fisura del Paladar , Injerto de Hueso Alveolar/métodos , Trasplante Óseo/métodos , Fisura del Paladar/diagnóstico por imagen , Fisura del Paladar/cirugía , Humanos , Ilion/trasplante , Resultado del Tratamiento
3.
Cleft Palate Craniofac J ; : 10556656221126268, 2022 Sep 13.
Artículo en Inglés | MEDLINE | ID: mdl-36112838

RESUMEN

OBJECTIVE: Psychosocial adjustment can be challenging for children with cleft lip with or without a cleft palate (CL ± P). Previous studies have linked social integration with self-acceptance and highlighted the impact of the parents' stress on self-acceptance. Teasing can be linked to children having difficulties explaining their diagnosis to others. This prospective research aimed to gain a better understanding of family communication about cleft, children's oral storytelling about their cleft, and explore their self-image and perceived familial acceptance. PARTICIPANTS: Parents and their children with CL ± P (N = 54; average age: 5.6 years). DESIGN: Semistructured interviews with parents and structured interviews with children were conducted regarding their oral storytelling focusing on scars from cleft lip surgery. Children completed a projective test to explore their self-image and perceptions of familial acceptance. Language screening was completed with the French Wechsler Preschool Primary Scale of Intelligence-Fourth Edition. RESULTS: Only 30% of children explained their cleft in a way appropriate for peers, including presence at birth, having had surgery, and scar location. Children's ability to explain their cleft was not related to language performance, which was in the average range of 84%. Children's cleft explanations were dependent on parents' narratives and education methods, including the use of verbal explanations and preoperative photographs. Children's storytelling was related to their self-image and perceived parental acceptance. CONCLUSION: Cleft teams should assist families in building their cleft story based on a complete explanation with photographs and a positive and accepting approach.

4.
J Craniofac Surg ; 32(7): e658-e660, 2021 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-34074922

RESUMEN

ABSTRACT: Acromegaly is a rare pathology linked to a pituitary adenoma responsible for excessive secretions of growth hormone and insulin growth factor 1 inducing an overgrowth of most tissues, especially those which are visible in the face. Main problem stands in the usual delayed diagnosis. The authors report the case of a patient operated twice of a rhinoplasty before and after the acromegaly diagnosis for a very excessive nose. They emphasize the technical difficulties to efficiently reduce all the nasal dimensions, the importance of the soft tissues quality, as they cover the nasal cartilaginous framework, and the absolute necessity of biological normalization to provide a stable and satisfactory result.


Asunto(s)
Acromegalia , Adenoma , Hormona de Crecimiento Humana , Neoplasias Hipofisarias , Rinoplastia , Acromegalia/etiología , Acromegalia/cirugía , Adenoma/cirugía , Humanos , Neoplasias Hipofisarias/cirugía
5.
Ann Chir Plast Esthet ; 66(4): 338-340, 2021 Aug.
Artículo en Francés | MEDLINE | ID: mdl-34303485

RESUMEN

Breast implant infection is a potential complication after surgery. This case reports an unusual infection. A patient undergoes a skin sparing mastectomy for a carcinoma with an immediate breast implant reconstruction. Few days after, she consults for pain, erythema and fluctuating breast collection. The implant is removed and a lavage is done. Bacteriological cultures yield Pasteurella Multocida. She has close contact with cats. Her cat scratches a drain. It looks crucial to educate patients before they go back home. Correct postoperative cares and avoid pets are important to prevent complications.


Asunto(s)
Implantes de Mama , Neoplasias de la Mama , Mamoplastia , Infecciones por Pasteurella , Pasteurella multocida , Animales , Implantes de Mama/efectos adversos , Gatos , Femenino , Humanos , Mastectomía
6.
BMC Pediatr ; 20(1): 230, 2020 05 18.
Artículo en Inglés | MEDLINE | ID: mdl-32423402

RESUMEN

BACKGROUND: The objective of this prospective, multidisciplinary and multicenter study was to explore the effect of a cleft lip, associated or not with a cleft palate, on parents, on parent-infant relationship, and on the baby's relational development. It also highlighted how the type of cleft and the timing of the surgery could impact this effect. METHOD: 158 infants, with Cleft lip with or without Palate, and their parents participated in this multicenter prospective cohort. Clinical evaluations were performed at 4 and 12 months postpartum. The impact on the parents and on the parent-infant relationship was evaluated by the Parenting Stress Index (PSI), the Edinburgh Post-partum Depression Scale (EPDS) and the Impact-on-Family Scale (IOFS). The relational development of the infant was assessed using the Alarm Distress Baby Scale (ADBB). The main criteria used to compare the infants were the severity of cleft and the time of surgery. RESULTS: The timing of surgery, the type of malformation or the care structure had no effect on social withdrawal behaviors of the child at 4 and 12 months postpartum (ADBB). Furthermore, early intervention significantly decreased maternal stress assessed with the PSI at 4 months. Parents for whom it had been possible to give a prenatal diagnosis were much better prepared to accept the waiting time between birth and the first surgical intervention (IOFS). Higher postpartum depression scores (EPDS) were found for both parents compared to the general population. CONCLUSION: A joint assessment of the mental health of both infants and parents is required in the follow-up of cleft lip and palate. Even if most families are remarkably resilient faced with this major cause of stress, a significant proportion of them could require help to deal with the situation, especially during this first year of follow-up. An assessment of the child's social withdrawal behaviour and of the parental stress and depression appears useful, in order to adapt care to infant and parent's needs. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT00993993. Registered 10/14/2009 <.


Asunto(s)
Labio Leporino , Fisura del Paladar , Niño , Labio Leporino/diagnóstico , Labio Leporino/cirugía , Fisura del Paladar/diagnóstico , Fisura del Paladar/cirugía , Femenino , Humanos , Lactante , Padres , Embarazo , Estudios Prospectivos
7.
Microsurgery ; 37(1): 38-43, 2017 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26037038

RESUMEN

PURPOSE: Extended and full-thickness abdominal wall defects are commonly reconstructed using free flaps. Published surgical outcomes involving the latissimus dorsi (LD) free flap procedure are limited and are less numerous than those with free flaps involving the thigh. The aim of this report was to describe the immediate and long-term evaluation of complex abdominal wall reconstruction using a LD free flap with mesh. PATIENTS AND METHODS: Between 2005 and 2013, nine patients with extended malignant tumors of the abdominal wall underwent surgeries. After the surgical resection, the mean defect size was 385 cm2 (range: 190-650 cm2 ). Full-thickness abdominal wall reconstruction was performed with a combination of LD free flaps and meshes. The immediate and long-term outcomes were assessed regarding the complications, sustainable strength of the abdominal wall and cancer recurrence. RESULTS: The meshes measured 927 cm2 in average (range: 500-1036 cm2 ). Eight Parietex Composite® and 1 Bard Collamend Implant® were used. No donor site complications occurred, and complete LD flap survival was achieved without partial necrosis or thrombosis. One obese patient who received a porcine dermis mesh developed an eventration four days postoperatively and exhibited a limited amount of abdominal skin necrosis around the flap. Two patients died from cancer evolution. After a mean follow-up of 60.4 months (range: 29-94 months), clinical evaluation of the abdomen revealed 2 patients without anomalies, 4 cases of abdominal bulging without functional discomfort and 1 case of major abdominal distension. CONCLUSIONS: Complex abdominal reconstruction with LD free flap and mesh allows extended satisfactory coverage with a low incidence of flap and donor site complications. However, patients should be advised of the significant risk of abdominal bulging. © 2014 Wiley Periodicals, Inc. Microsurgery 37:38-43, 2017.


Asunto(s)
Neoplasias Abdominales/cirugía , Pared Abdominal/cirugía , Colgajos Tisulares Libres/trasplante , Procedimientos de Cirugía Plástica/métodos , Músculos Superficiales de la Espalda/trasplante , Mallas Quirúrgicas , Adenocarcinoma/cirugía , Adulto , Anciano , Femenino , Fibromatosis Agresiva/cirugía , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/epidemiología , Procedimientos de Cirugía Plástica/instrumentación , Sarcoma/cirugía , Teratoma/cirugía , Resultado del Tratamiento
8.
Microsurgery ; 36(1): 42-8, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25732779

RESUMEN

BACKGROUND: The transverse musculocutaneous gracilis (TMG) flap has become a common solution for breast reconstruction. However, the safe skin paddle limits are not yet understood. In this study, we attempted to address this issue based on our experiences with inferior and posterior skin paddle extension. METHODS: Forty-four breast reconstructions with TMG flaps performed between November 2010 and January 2014 were analyzed retrospectively. For the first 20 cases, the flap skin paddle was extended 3 cm posteriorly to the middle thigh (group 1). For the next 20 flaps (group 2), the posterior tip was limited to this line, whereas more fat was recruited inferiorly. In the four cases of group 3, the skin flap was extended posteriorly with a second vascular pedicle from the profunda artery perforator (PAP) flap. The weights and the dimensions of the flaps, operating durations, and postoperative complications of the entire series were analyzed. Groups 1 and 2 were statistically compared. RESULTS: Flap complications were statistically more frequent in group 1 compared with group 2 (45 vs. 0%, P = 0.0012); 40% posterior flap tip necrosis was observed in group 1. Conversely, donor site complications were statistically more frequent in group 2 than in group 1 (40 vs. 5%, P = 0.019) with 35% inner thigh dehiscence. In the TMG with extended PAP flap group, the operating duration was 77 min longer compared with the rest of the series with no donor site complications. In one case, limited necrosis occurred at the anterior skin tip. CONCLUSIONS: Harvesting the posterior portion of the TMG up to the middle of the posterior thigh may lead to partial flap necrosis. Extending subcutaneous fat removal under the inferior skin incision may increase the risk of donor site complications. Adding a second vascular pedicle from the PAP flap may improve posterior TMG tip perfusion at the expense of a longer operation.


Asunto(s)
Mamoplastia/métodos , Colgajo Miocutáneo , Colgajo Perforante , Complicaciones Posoperatorias/prevención & control , Adulto , Femenino , Humanos , Persona de Mediana Edad , Estudios Retrospectivos , Muslo/cirugía
9.
Microsurgery ; 35(4): 295-9, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25382588

RESUMEN

PURPOSE: The purpose of this report was to present the results of comparisons of anastomotic data and flap complications in the use of venous coupler in breast reconstruction with the transverse musculocutaneous gracilis (TMG) flap and the deep inferior epigastric perforator (DIEP) flap. METHODS: Over a three-year period, 95 patients suffering from breast cancer were treated with mastectomy and breast reconstruction using free flaps. We performed 121 mechanical venous anastomoses for 105 flap procedures (80 DIEP and 25 TMG). The coupler size, anastomotic duration, number of anastomoses and postoperative complications were assessed for the entire series. RESULTS: The coupling device was perfectly suitable for all end-to-end anastomoses between the vein(s) of the flap and the internal mammary vein(s). No venous thrombosis occurred. The mean anastomotic time did not significantly differ between the DIEP (330 seconds) and TMG flap procedures (352 seconds) (P = 0.069). Additionally, there were no differences in coupling time observed following a comparison of seven coupler sizes (P = 0.066). The mean coupler size used during the TMG flap procedure was smaller than that used with the DIEP (2.4 mm versus 2.8 mm) (P < 0.001). The mean size was also smaller when double venous anastomoses were required compared to single anastomosis (2.4 mm versus 2.9 mm) (P < 0.001). The double branching was more frequent with the TMG flap (28%) than with the DIEP flap (11%). CONCLUSIONS: The coupler size used was smaller for the TMG procedure and when double venous anastomosis was performed. Additionally, anastomotic time was not affected by the flap type or coupler size used or by anastomosis number.


Asunto(s)
Mama/irrigación sanguínea , Arterias Epigástricas/cirugía , Colgajos Tisulares Libres/irrigación sanguínea , Mamoplastia/métodos , Venas/cirugía , Adulto , Anastomosis Quirúrgica , Mama/cirugía , Femenino , Colgajos Tisulares Libres/trasplante , Humanos , Mastectomía , Persona de Mediana Edad , Evaluación de Resultado en la Atención de Salud , Complicaciones Posoperatorias , Estudios Retrospectivos , Venas/anatomía & histología
10.
BMC Pediatr ; 12: 65, 2012 Jun 08.
Artículo en Inglés | MEDLINE | ID: mdl-22682069

RESUMEN

BACKGROUND: The birth of a child with a cleft lip, whether or not in association with a cleft palate, is a traumatic event for parents. This prospective, multidisciplinary and multi-centre study aims to explore the perceptions and feelings of parents in the year following the birth of their child, and to analyse parent-child relationships. Four inclusion centres have been selected, differing as to the date of the first surgical intervention, between birth and six months. The aim is to compare results, also distinguishing the subgroups of parents who were given the diagnosis in utero and those who were not. METHODS/DESIGN: The main hypothesis is that the longer the time-lapse before the first surgical intervention, the more likely are the psychological perceptions of the parents to affect the harmonious development of their child. Parents and children are seen twice, when the child is 4 months (T0) and when the child is one year old (T1). At these two times, the psychological state of the child and his/her relational abilities are assessed by a specially trained professional, and self-administered questionnaires measuring factors liable to affect child-parent relationships are issued to the parents. The Alarme Détresse BéBé score for the child and the Parenting Stress Index score for the parents, measured when the child reaches one year, will be used as the main criteria to compare children with early surgery to children with late surgery, and those where the diagnosis was obtained prior to birth with those receiving it at birth. DISCUSSION: The mental and psychological dimensions relating to the abnormality and its correction will be analysed for the parents (the importance of prenatal diagnosis, relational development with the child, self-image, quality of life) and also, for the first time, for the child (distress, withdrawal). In an ethical perspective, the different time lapses until surgery in the different protocols and their effects will be analysed, so as to serve as a reference for improving the quality of information during the waiting period, and the quality of support provided for parents and children by the healthcare team before the first surgical intervention. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT00993993.


Asunto(s)
Actitud Frente a la Salud , Labio Leporino/psicología , Fisura del Paladar/psicología , Relaciones Padres-Hijo , Padres/psicología , Procedimientos de Cirugía Plástica , Listas de Espera , Labio Leporino/complicaciones , Labio Leporino/diagnóstico , Labio Leporino/cirugía , Fisura del Paladar/complicaciones , Fisura del Paladar/diagnóstico , Fisura del Paladar/cirugía , Protocolos Clínicos , Femenino , Humanos , Lactante , Recién Nacido , Análisis Multivariante , Responsabilidad Parental/psicología , Embarazo , Diagnóstico Prenatal , Pruebas Psicológicas , Estrés Psicológico , Factores de Tiempo
11.
J Craniomaxillofac Surg ; 49(10): 914-922, 2021 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-34187731

RESUMEN

The primary aim of this study was to demonstrate whether primary rhinoplasty shows aesthetic and psychosocial advantages for children with a complete unilateral cleft lip and palate. The second aim was to determine the satisfaction levels concerning the dentofacial appearance. Group A corresponded to patients from a center specialised in primary cheilo-rhinoplasty with 20 years' experience and Group B to patients who did not benefit from primary rhinoplasty. Children and their parents filled in a custom-designed satisfaction questionnaire on dentofacial appearance and its psychosocial impact. The variables studied were the main criterion (the nose) and secondary criteria (the upper lip, the smile, the profile and the face as a whole). 56 families consented to be involved in the study. The children did not rate statistically differently their social relationships if they had primary rhinoplasty or not. Parents however expressed very different views. They considered the nasal appearance of the children who had primary rhinoplasty as statistically more attractive and evaluated their psychosocial experience as significantly better. For the other parts of the face, in both groups, satisfaction levels of dentofacial appearance and psychosocial comfort were good (scores above 80/100). Yet, 44% of the families would go for further interventions, especially concerning the nose (13% of whom were in Group A and 42% in Group B). Within the limitations of this study, primary rhinoplasty seems to improve the patient's well-being and social life and, therefore, should be considered whenever appropriate.


Asunto(s)
Labio Leporino , Fisura del Paladar , Rinoplastia , Niño , Labio Leporino/cirugía , Fisura del Paladar/cirugía , Estética Dental , Humanos , Nariz/cirugía , Resultado del Tratamiento
12.
Acta Biomater ; 102: 259-272, 2020 01 15.
Artículo en Inglés | MEDLINE | ID: mdl-31811957

RESUMEN

Islet transplantation is one of the most efficient cell therapies used in clinics and could treat a large proportion of patients with diabetes. However, it is limited by the high requirement of pancreas necessary to provide the sufficient surviving islet mass in the hepatic tissue and restore normoglycaemia. Reduction in organ procurement requirements could be achieved by extrahepatic transplantation using a biomaterial that enhances islet survival and function. We report a plasma-supplemented hydroxypropyl methylcellulose (HPMC) hydrogel, engineered specifically using a newly developed technique for intra-omental islet infusion, known as hOMING (h-Omental Matrix Islet filliNG). The HPMC hydrogel delivered islets with better performance than that of the classical intrahepatic infusion. After the validation of the HPMC suitability for islets in vivo and in vitro, plasma supplementation modified the rheological properties of HPMC without affecting its applicability with hOMING. The biomaterial association was proven to be more efficient both in vitro and in vivo, with better islet viability and function than that of the current clinical intrahepatic delivery technique. Indeed, when the islet mass was decreased by 25% or 35%, glycaemia control was observed in the group of plasma-supplemented hydrogels, whereas no regulation was observed in the hepatic group. Plasma gelation, observed immediately post infusion, decreased anoïkis and promoted vascularisation. To conclude, the threshold mass for islet transplantation could be decreased using HPMC-Plasma combined with the hOMING technique. The simplicity of the hOMING technique and the already validated use of its components could facilitate its transfer to clinics. STATEMENT OF SIGNIFICANCE: One of the major limitations for the broad deployment of current cell therapy for brittle type 1 diabetes is the islets' destruction during the transplantation process. Retrieved from their natural environment, the islets are grafted into a foreign tissue, which triggers massive cell loss. It is mandatory to provide the islets with an 3D environment specifically designed for promoting isletimplantation to improve cell therapy outcomes. For this aim, we combined HPMC and plasma. HPMC provides suitable rheological properties to the plasma to be injectable and be maintained in the omentum. Afterwards, the plasma polymerises around the graft in vivo, thereby allowing their optimal integration into their transplantation site. As a result, the islet mass required to obtain glycaemic control was reduced by 35%.


Asunto(s)
Diabetes Mellitus Experimental/cirugía , Excipientes/farmacología , Control Glucémico/métodos , Hidrogeles/farmacología , Derivados de la Hipromelosa/farmacología , Trasplante de Islotes Pancreáticos , Animales , Difusión , Excipientes/química , Hidrogeles/química , Derivados de la Hipromelosa/química , Islotes Pancreáticos/citología , Masculino , Epiplón/cirugía , Oxígeno/química , Oxígeno/metabolismo , Ratas Endogámicas Lew , Ratas Wistar , Viscosidad
13.
Cell Transplant ; 27(8): 1289-1293, 2018 08.
Artículo en Inglés | MEDLINE | ID: mdl-29996661

RESUMEN

Following the tremendous development of hydrogels for cell therapy, there is now a growing need for surgical techniques to validate in vivo scaffold benefits for islet transplantation. Therefore, we propose a newly designed surgical procedure involving the injection of hydrogel-embedded pancreatic islets in the omentum, which is considered a favorable environment for cell survival and function. Our technique, called h-Omental Matrix Islet filliNG (hOMING) was designed to test the benefits of hydrogel on islet survival and function in vivo. Islets were implanted in the omentum of diabetic rats using the hOMING technique and alginate as an islet carrier. Blood glucose and C-peptide levels were recorded to assess graft function. After 2 months, grafts were explanted and studied using insulin and vessel staining. All rats that underwent hOMING exhibited graft function characterized by a glycemia decrease and a C-peptidemia increase ( P < 0.001 compared with preoperative levels). Furthermore, hOMING appeared to preserve islet morphology and insulin content and allowed the proper revascularization of grafted islets. The results suggest that hOMING is a viable and promising approach to test in vivo the benefits of hydrogel administration for islet transplantation into the omental tissue.


Asunto(s)
Alginatos/química , Diabetes Mellitus Experimental/terapia , Hidrogeles/química , Trasplante de Islotes Pancreáticos/métodos , Islotes Pancreáticos/citología , Epiplón/cirugía , Andamios del Tejido/química , Animales , Glucemia/metabolismo , Células Inmovilizadas/citología , Células Inmovilizadas/metabolismo , Células Inmovilizadas/trasplante , Supervivencia de Injerto , Islotes Pancreáticos/metabolismo , Masculino , Ratas Endogámicas Lew
14.
Biomed Mater Eng ; 28(s1): S15-S27, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28372275

RESUMEN

Predictive theoretical-numerical modeling of the behavior and evolution of biological tissue is a difficult task since many of the required knowledge tools (experimental, theoretical and numerical) are still not well understood. We present here some methodologies and results specific to multiscale and multiphysics numerical modeling of biological tissues applied to the predictive behavior of cortical veins depending on their local constituents' microstructure and for bone remodeling and reconstruction as a function of the local mechanobiology. Although further work is required to improve the accuracy of the developed models, the proposed approaches highlight their potential usefulness for understanding the mechanical-biological couplings, short and long term predictions of biological evolutions as well as possible further transfer to medical applications.


Asunto(s)
Remodelación Ósea , Corteza Cerebral/irrigación sanguínea , Simulación por Computador , Modelos Biológicos , Venas/fisiología , Fenómenos Biomecánicos , Huesos/anatomía & histología , Corteza Cerebral/anatomía & histología , Humanos , Modelos Anatómicos , Estrés Mecánico , Venas/anatomía & histología
15.
Eur J Cardiothorac Surg ; 49(3): 1008-9, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25825263

RESUMEN

Radical resection of an extended malignant sarcoma of the chest wall requires full-thickness thoracic chest wall reconstruction. Reconstruction is tedious in the case of posteriorly located tumours, because the ipsilateral pedicled myocutaneous latissimus dorsi flap is involved and hence not usable for soft tissue coverage. We report an original case of a left giant dorsal chondrosarcoma originating from the 11th costovertebral joint. After extended resection and skeletal reconstruction, soft tissue coverage was achieved with an original contralateral free flap encompassing both latissimus dorsi and serratus anterior muscles. The flap pedicle was anastomosed to the ipsilateral thoracodorsal vessels.


Asunto(s)
Condrosarcoma/cirugía , Colgajos Tisulares Libres/cirugía , Procedimientos de Cirugía Plástica/métodos , Músculos Superficiales de la Espalda/cirugía , Neoplasias Torácicas/cirugía , Pared Torácica/cirugía , Adulto , Humanos , Masculino
17.
J Craniomaxillofac Surg ; 44(1): 21-6, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26646636

RESUMEN

BACKGROUND AND PURPOSE: Although alveolar cleft bone grafting is the most widely accepted approach, controversies remain on the operative timing. METHODS: A consecutive retrospective series of 28 patients who received alveolar bone grafting was examined and divided into 2 groups depending on the age at the time of bone graft. Group A (14 patients) was operated at a mean age of 5.2 years [range, 4-7] and Group B (14 patients) at a mean age of 10 years [range, 8.5-13]. All the children were assessed clinically and by Cone Beam Computed Tomography (CBCT) before bone grafting and 6 months post-operatively. Cleft and bone graft dimensions, volumes were assessed using Osirix v.3.9.2. Residual bone graft coefficient (Bone Graft Volume on 6-months Postoperative CBCT/Alveolar Cleft Volume) was calculated. Complications, tooth movement or dental agenesis were also reported. RESULTS: The sample was uniform within both groups, considering cleft forms, pre-surgical fistula rate and cleft volume. Residual bone graft coefficient reached 63.3% in Group A and 46.2% in Group B (p = 0.012). Results of residual bone graft are also influenced by tooth eruption through the graft (p = 0.007 in Group A and p = 0.02 in Group B). CONCLUSIONS: This 3D analysis highlighted higher success of alveolar bone grafts when children are operated earlier around 5 years. LEVEL OF EVIDENCE: Therapeutic study. Level III/retrospective comparative study.


Asunto(s)
Injerto de Hueso Alveolar , Labio Leporino/cirugía , Fisura del Paladar/cirugía , Trasplante Óseo , Niño , Preescolar , Tomografía Computarizada de Haz Cónico , Femenino , Humanos , Masculino , Estudios Retrospectivos
18.
J Craniomaxillofac Surg ; 44(2): 94-103, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26712484

RESUMEN

BACKGROUND AND PURPOSE: Cleft surgery is marked by all the controversies and the multiplication of protocols, as it has been shown by the Eurocleft study. The objective of this pilot study is to start a comparison and analyzing procedure between primary surgical protocols in French centers. METHODS: Four French centers with different primary surgical protocols for cleft lip and palate repair, have accepted to be involved in this retrospective study. In each center, 20 consecutive patients with complete cleft lip and palate (10 UCLP, 10 BCLP per center), non syndromic, have been evaluated at a mean age of 5 [range, 4-6]. In this second part, maxillary growth and palatine morphology were assessed on clinical examination and on dental casts (Goslon score). Speech was also evaluated clinically (Borel-maisonny classification) and by Aerophonoscope. RESULTS: Veau-Wardill-Killner palatoplasty involves a higher rate of transversal maxillary deficiency and retromaxillary. The fistula rate is statistically lower with tibial periosteum graft hard palate closure but this technique seems to give retromaxillary. Malek and Talmant two-stage-palatoplasty techniques reach Goslon scores of 1 or 2. Considering speech, Sommerlad intravelar veloplasty got higher outcomes. CONCLUSIONS: Primary results. Extension to other centers required. The two-stage palatoplasty, including a Sommerlad intravelar veloplasty seems to have the less negative impact on maxillary growth, and to give good speech outcomes. LEVEL OF EVIDENCE: Therapeutic study. Level III/retrospective multicenter comparative study.


Asunto(s)
Labio Leporino/cirugía , Fisura del Paladar/cirugía , Niño , Femenino , Humanos , Masculino , Maxilar/crecimiento & desarrollo , Paladar Duro/cirugía , Proyectos Piloto , Estudios Retrospectivos , Habla , Resultado del Tratamiento
19.
J Plast Reconstr Aesthet Surg ; 68(1): e1-6, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25456283

RESUMEN

BACKGROUND: A transverse musculocutaneous gracilis flap provides good autologous reconstruction for small- and medium-sized breasts. Although the procedure is well adapted for bilateral breast reconstruction, no publication has specifically addressed simultaneous bilateral cases. METHODS: From 2010 to 2014, the authors performed seven simultaneous bilateral breast reconstructions using transverse musculocutaneous gracilis flaps. The results with respect to operative data, immediate complications, second-stage reconstruction, and patient satisfaction after >1 year of follow-up were studied retrospectively. RESULTS: The mean operative time was 7 h and 48 min (range, 6-9 h). Three minor complications occurred: two cases of limited flap necrosis and one case of donor-site wound dehiscence. Surgical revision was not required, and there was no flap failure. A second-stage operation was performed in 71% of the patients to improve the aesthetic results and flap volume. On average, 167 cm(3) of fat was injected per breast. After a mean follow-up of 27 months, the satisfaction rate was 86% without significant functional deficits. CONCLUSIONS: A transverse musculocutaneous gracilis flap is an effective and safe option for simultaneous bilateral reconstruction. The operating time is shorter than that for other autologous procedures with similar complication rates and high patient satisfaction levels.


Asunto(s)
Neoplasias de la Mama/terapia , Mamoplastia/métodos , Mastectomía Subcutánea/métodos , Colgajo Miocutáneo/trasplante , Adulto , Neoplasias de la Mama/patología , Estudios de Cohortes , Terapia Combinada , Femenino , Estudios de Seguimiento , Rechazo de Injerto , Humanos , Mamoplastia/efectos adversos , Persona de Mediana Edad , Colgajo Miocutáneo/irrigación sanguínea , Tempo Operativo , Satisfacción del Paciente/estadística & datos numéricos , Cuidados Posoperatorios/métodos , Complicaciones Posoperatorias/fisiopatología , Complicaciones Posoperatorias/cirugía , Estudios Retrospectivos , Medición de Riesgo , Factores de Tiempo , Trasplante Autólogo , Resultado del Tratamiento , Adulto Joven
20.
J Plast Reconstr Aesthet Surg ; 68(1): e7-12, 2015 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-25465136

RESUMEN

BACKGROUND: The lotus petal flap procedure is widely used for vulvovaginal reconstructions after gynecologic resections, but its effectiveness for posterior perineal coverage and filling is not yet well defined. METHODS: We conducted a retrospective evaluation of 10 lotus petal flap procedures performed between 2010 and 2014. Six patients were operated upon with posterior transpositions of unilateral (n = 2) or bilateral (n = 4) supra-fascial flaps. The patient demographics, comorbidities, and previous surgical treatments were surveyed. The postoperative outcomes, including length of stay, time of healing, and complications, were analyzed. RESULTS: Lotus petal flaps were indicated for filling of the chronic perineal cavity (n = 4) and for skin resurfacing (n = 2). The mean patient age was 61.5 years, and four patients previously underwent radiotherapy. The total operative time was 2.2 h on average. No wound complications or flap necrosis instances occurred during the follow-up consultations, which occurred at a mean of 20.5 months. The hospital stay duration was 11.3 days, and the duration of healing was 35.2 days, on average. Each flap transposition achieved the sustainable perineal reconstruction goal. CONCLUSIONS: The supra-fascial lotus petal flap is an easy and safe procedure for posterior perineal reconstructions. Whether for an immediate or a delayed operation, unilateral or bilateral flap harvestings allow for effective coverage and filling. Furthermore, the donor-site morbidity remained low because the scars were hidden in the gluteal fold.


Asunto(s)
Perineo/cirugía , Procedimientos de Cirugía Plástica/métodos , Colgajos Quirúrgicos/irrigación sanguínea , Cicatrización de Heridas/fisiología , Adulto , Anciano , Nalgas/cirugía , Estudios de Cohortes , Femenino , Estudios de Seguimiento , Rechazo de Injerto , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Medición de Riesgo , Recolección de Tejidos y Órganos/métodos , Resultado del Tratamiento
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