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1.
J Couns Psychol ; 66(3): 328-340, 2019 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-30589281

RESUMEN

Over the past decade, research on work as a calling has seen a rapid growth, with hundreds of empirical articles on the topic having been published. Until recently, however, there has been no comprehensive theoretical model of work as a calling to guide research. Duffy, Dik, Douglass, England, and Velez (2018) published the Work as Calling Theory (WCT), which provides a comprehensive model of the predictors and outcomes of living out a calling. The present study provides the first empirical examination of the 20 propositions outlined within the predictor portion of this model. Using data collected from a sample of 424 employed adults living in the United States, from diverse social class backgrounds and occupations, we conducted latent variable structural equation modeling to evaluate the model propositions. Overall, we found full (17) and partial (1) support for 18 of the 20 model propositions, which included direct effects along with mediating and moderating effects. Person-environment fit, career commitment, and work meaning appear to be critical in helping to translate a perceived calling and access to opportunity into a lived calling. Additionally, calling motivation, organizational support, and job crafting may play a key role in helping employees with a calling experience more fit with their work environments. Taking these findings into consideration, we explore practical implications for career counselors and employers and highlight future directions for scholars using the WCT. (PsycINFO Database Record (c) 2019 APA, all rights reserved).


Asunto(s)
Empleo/psicología , Satisfacción en el Trabajo , Adulto , Femenino , Humanos , Masculino , Motivación , Ocupaciones , Estados Unidos , Lugar de Trabajo/psicología
2.
J Couns Psychol ; 66(2): 195-209, 2019 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-30714744

RESUMEN

The psychology of working theory (PWT; Duffy, Blustein, Diemer, & Autin, 2016) provides a framework to understand predictors and outcomes of decent work. Given that basic need satisfaction is hypothesized to be a primary mediator in the link between decent work and well-being, it is essential to have valid and reliable scales that are consistent with the PWT framework. In the current study, we developed the Work Needs Satisfaction Scales, a set of instruments designed to measure satisfaction of survival, social contribution, and self-determination needs from a PWT perspective. In Study 1 (N = 345), a pool of items was developed and exploratory factor analysis was conducted, resulting in five 4-item scales representing survival need satisfaction, social contribution need satisfaction, and three components of self-determination need satisfaction (i.e., autonomy, competence, relatedness). In Study 2 (N = 476), we used confirmatory factor analysis to test 4 different structural models, finding that there were no significant differences between models. Thus, results offer a flexible 5-factor model, the structure of which may be adapted based on theory and researcher needs. Authors provide theory-driven recommendations on how to best use choice of structural models for PWT research. Finally, we demonstrated convergent, discriminant, and concurrent validity for the structural model most consistent with the PWT. Implications for research and practice are discussed. (PsycINFO Database Record (c) 2019 APA, all rights reserved).


Asunto(s)
Satisfacción en el Trabajo , Encuestas y Cuestionarios/normas , Lugar de Trabajo/psicología , Adulto , Análisis Factorial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Satisfacción Personal , Reproducibilidad de los Resultados , Adulto Joven
3.
J Couns Psychol ; 65(4): 423-439, 2018 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-29999369

RESUMEN

Perceiving work as a calling has been positioned as a key pathway to enhancing work-related well-being. However, no formal theory exists attempting to explain predictors and outcomes of living a calling at work. To address this important gap, this article introduces a theoretical, empirically testable model of work as a calling - the Work as Calling Theory (WCT) - that is suitable for the contemporary world of work. Drawing from research and theory in counseling, vocational, multicultural, and industrial-organizational psychology, as well as dozens of quantitative and qualitative studies on calling, the WCT is presented in three parts: (a) predictors of living a calling, (b) variables that moderate and mediate the relation of perceiving a calling to living a calling, and (c) positive (job satisfaction, job performance) and potentially negative (burnout, workaholism, exploitation) outcomes that result from living a calling. Finally, practical implications are suggested for counselors and managers, who respectively may seek to help clients and employees live a calling. (PsycINFO Database Record


Asunto(s)
Selección de Profesión , Satisfacción en el Trabajo , Modelos Teóricos , Apoyo Social , Rendimiento Laboral , Agotamiento Profesional/epidemiología , Agotamiento Profesional/psicología , Humanos
4.
J Couns Psychol ; 65(3): 280-293, 2018 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-29672079

RESUMEN

The present study tested key tenets of the Psychology of Working Theory (PWT) in a sample of 526 racially and ethnically diverse employed adults. The authors investigated how economic resources and marginalization predicted decent work through experiences of work volition and career adaptability. Support for the hypotheses was mixed. There was a direct, negative relation between marginalization and decent work; a direct, positive relation between economic resources and work volition; and a direct, negative relation between marginalization and work volition. There was a positive relation between work volition and career adaptability as well as with decent work. Work volition was also found to significantly mediate the relations between marginalization and economic resources to decent work. These results suggest that the primary reason why greater economic resources and lower experiences of marginalization predict engaging in decent work is attributable to an increased sense of choice in one's career decision making. Results suggest the need for further investigation using the PWT to understand how racially and ethnically diverse employed adults secure decent work. Practical implications are discussed. (PsycINFO Database Record


Asunto(s)
Diversidad Cultural , Estatus Económico , Empleo/psicología , Etnicidad/psicología , Teoría Psicológica , Grupos Raciales/psicología , Adulto , Selección de Profesión , Estudios Transversales , Estatus Económico/tendencias , Empleo/economía , Empleo/tendencias , Femenino , Humanos , Masculino , Grupos Raciales/etnología , Marginación Social/psicología , Percepción Social , Volición
5.
J Couns Psychol ; 64(1): 1-11, 2017 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-27929299

RESUMEN

Research has found perceived discrimination to be a risk factor for mental health concerns among lesbian, gay, and bisexual (LGB) people, but less clarity exists linking perceived discrimination with well-being outcomes. Building from Meyer's (2003) minority stress model, the present study examined the links between perceived discrimination and the 3 components of subjective well-being: positive affect, negative affect, and life satisfaction. Self-esteem and stigma consciousness were explored as empirically and theoretically implied moderators. In a sample of 368 LGB people, structural equation modeling results suggested that discrimination was not significantly associated with positive affect or life satisfaction but had a significant positive relation with negative affect. Self-esteem moderated the associations between discrimination and positive and negative affect, and stigma consciousness moderated the link with negative affect. Practical implications and directions for future research are discussed. (PsycINFO Database Record


Asunto(s)
Bisexualidad/psicología , Prejuicio/psicología , Minorías Sexuales y de Género/psicología , Adulto , Femenino , Humanos , Masculino , Salud Mental , Calidad de Vida/psicología , Autoimagen , Conducta Sexual/psicología , Estigma Social
6.
J Couns Psychol ; 64(5): 550-559, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28333474

RESUMEN

Research has found heterosexist discrimination negatively relates to vocational outcomes among lesbian, gay, and bisexual (LGB) people, but no known study has examined how heterosexist discrimination relates to the attainment of decent work. Building from the Psychology of Working Theory, which proposes that specific forms of marginalization coupled with economic constraints limit a person's ability to secure decent work, the present study examined theoretically hypothesized pathways to decent work among a sample of employed sexual minority adults. Heterosexist discrimination and social class were examined as direct predictors of decent work, and indirect links were examined via work volition and career adaptability. Among our sample of 218 sexual minority people, structural equation modeling results suggested heterosexist discrimination and social class directly-and indirectly through work volition-predicted decent work. Practical implications and directions for future research are discussed. (PsycINFO Database Record


Asunto(s)
Empleo/psicología , Prejuicio/psicología , Minorías Sexuales y de Género/psicología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Modelos Psicológicos , Adulto Joven
7.
J Couns Psychol ; 64(2): 206-221, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28165257

RESUMEN

Decent work is positioned as the centerpiece of the recently developed Psychology of Working Theory (PWT; Duffy, Blustein, Diemer, & Autin, 2016). However, to date, no instrument exists which assesses all 5 components of decent work from a psychological perspective. In the current study, we developed the Decent Work Scale (DWS) and demonstrated several aspects of validity with 2 samples of working adults. In Study 1 (N = 275), a large pool of items were developed and exploratory factor analysis was conducted resulting in a final 15-item scale with 5 factors/subscales corresponding to the 5 components of decent work: (a) physically and interpersonally safe working conditions, (b) access to health care, (c) adequate compensation, (d) hours that allow for free time and rest, and (e) organizational values that complement family and social values. In Study 2 (N = 589), confirmatory factor analysis demonstrated that a 5-factor, bifactor model offered the strongest and most parsimonious fit to the data. Configural, metric, and scalar invariance models were tested demonstrating that the structure of the instrument did not differ across gender, income, social class, and majority/minority racial/ethnic groups. Finally, the overall scale score and 5 subscale scores correlated in the expected directions with similar constructs supporting convergent and discriminant evidence of validity, and subscale scores evidenced predictive validity in the prediction of job satisfaction, work meaning, and withdrawal intentions. The development of this scale provides a useful tool for researchers and practitioners seeking to assess the attainment of decent work among employed adults. (PsycINFO Database Record


Asunto(s)
Selección de Profesión , Movilidad Laboral , Satisfacción en el Trabajo , Psicometría/estadística & datos numéricos , Encuestas y Cuestionarios , Carga de Trabajo/psicología , Lugar de Trabajo , Adulto , Femenino , Accesibilidad a los Servicios de Salud , Humanos , Renta , Relaciones Interpersonales , Masculino , Persona de Mediana Edad , Salud Laboral , Teoría Psicológica , Estados Unidos
8.
Bioscience ; 65(7): 651-666, 2015 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-26955081

RESUMEN

Understanding the environmental drivers of zoonotic reservoir and human interactions is crucial to understanding disease risk, but these drivers are poorly predicted. We propose a mechanistic understanding of human-reservoir interactions, using hantavirus pulmonary syndrome as a case study. Crucial processes underpinning the disease's incidence remain poorly studied, including the connectivity among natural and peridomestic deer mouse host activity, virus transmission, and human exposure. We found that disease cases were greatest in arid states and declined exponentially with increasing precipitation. Within arid environments, relatively rare climatic conditions (e.g., El Niño) are associated with increased rainfall and reservoir abundance, producing more frequent virus transmission and host dispersal. We suggest that deer mice increase their occupancy of peridomestic structures during spring-summer, amplifying intraspecific transmission and human infection risk. Disease incidence in arid states may increase with predicted climatic changes. Mechanistic approaches incorporating reservoir behavior, reservoir-human interactions, and pathogen spillover could enhance our understanding of global hantavirus ecology, with applications to other directly transmitted zoonoses.

9.
J Couns Psychol ; 61(4): 605-15, 2014 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-25181588

RESUMEN

The current study examined the link between living a calling and career commitment, work meaning, and job satisfaction with a diverse group of working adults at 3 time points over a 6-month period. Using structural equation modeling, 3 models were tested that hypothesized that living a calling would predict career commitment, work meaning, and job satisfaction over time. However, counter to hypotheses, living a calling was best positioned as an outcome of each of these variables. Specifically, living a calling at Time 2 and Time 3 was significantly predicted by career commitment, work meaning, and job satisfaction at Time 1 and Time 2, respectively. Time 2 living a calling did predict Time 3 work career commitment and work meaning, but these effects were small. Results suggest that over time, individuals who feel committed to their career, derive more meaning from their work, and are more satisfied with their jobs are more likely to feel they are living a calling. Practical implications are discussed.


Asunto(s)
Selección de Profesión , Satisfacción en el Trabajo , Calidad de Vida/psicología , Identificación Social , Adolescente , Adulto , Anciano , Femenino , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Adulto Joven
10.
Oecologia ; 169(2): 431-9, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22218940

RESUMEN

How pathogens affect their hosts is a key question in infectious disease ecology, and it can have important influences on the spread and persistence of the pathogen. Sin Nombre virus (SNV) is the etiological agent of hantavirus pulmonary syndrome (HPS) in humans. A better understanding of SNV in its reservoir host, the deer mouse, could lead to improved predictions of the circulation and persistence of the virus in the mouse reservoir, and could help identify the factors that lead to increased human risk of HPS. Using mark-recapture statistical modeling on longitudinal data collected over 15 years, we found a 13.4% decrease in the survival of male deer mice with antibodies to SNV compared to uninfected mice (both male and female). There was also an additive effect of breeding condition, with a 21.3% decrease in survival for infected mice in breeding condition compared to uninfected, non-breeding mice. The data identified that transmission was consistent with density-dependent transmission, implying that there may be a critical host density below which SNV cannot persist. The notion of a critical host density coupled with the previously overlooked disease-induced mortality reported here contribute to a better understanding of why SNV often goes extinct locally and only seems to persist at the metapopulation scale, and why human spillover is episodic and hard to predict.


Asunto(s)
Peromyscus/virología , Enfermedades de los Roedores/mortalidad , Enfermedades de los Roedores/virología , Virus Sin Nombre/patogenicidad , Animales , Reservorios de Enfermedades , Femenino , Síndrome Pulmonar por Hantavirus/transmisión , Humanos , Estudios Longitudinales , Masculino , Modelos Estadísticos , Montana , Densidad de Población , Enfermedades de los Roedores/transmisión , Zoonosis/transmisión
11.
Rev Chilena Infectol ; 29(2): 200-6, 2012 Apr.
Artículo en Español | MEDLINE | ID: mdl-22689036

RESUMEN

Oligoryzomys longicaudatus is the main reservoir of Andes virus (AND), which causes hantavirus pulmonary syndrome in Patagonia. The factors associated with the presence of antibodies against AND in this species are unknown. This study used a logistic regression model to analyze which characteristics of O. longicaudatus, captured in northern Argentinean Patagonia, led to an increased probability of an animal having antibodies against AND and to relate these characteristics to possible mechanisms of transmission of the virus within the population. Sex, age, body mass, and wounds were important predictors regarding the presence of antibodies against AND within O. longicaudatus populations. The probability of a wounded male O. longicaudatus adult having AND antibodies increased in parallel with the body mass. The probability of having antibodies was more than 80% in individuals with body masses above 44 gram. However, the possible transmission mechanism of AND within O. longicaudatus population is still uncertain and further studies involving a larger number of individuals and prolonged monitoring including the process of seroconversion are needed.


Asunto(s)
Anticuerpos Antivirales/sangre , Reservorios de Enfermedades/veterinaria , Infecciones por Hantavirus/veterinaria , Orthohantavirus/inmunología , Enfermedades de los Roedores/virología , Sigmodontinae/virología , Animales , Argentina , Índice de Masa Corporal , Reservorios de Enfermedades/virología , Femenino , Infecciones por Hantavirus/inmunología , Modelos Logísticos , Masculino , Estudios Retrospectivos , Enfermedades de los Roedores/inmunología , Estaciones del Año , Estudios Seroepidemiológicos
12.
Oecologia ; 166(3): 713-21, 2011 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-21170746

RESUMEN

The effect of intermittently occurring, non-reservoir host species on pathogen transmission and prevalence in a reservoir population is poorly understood. We investigated whether voles, Microtus spp., which occur intermittently, influenced estimated standing antibody prevalence (ESAP) to Sin Nombre hantavirus (SNV, Bunyaviridae: Hantavirus) among deer mice, Peromyscus maniculatus, whose populations are persistent. We used 14 years of data from central Montana to investigate whether ESAP among deer mice was related to vole presence or abundance while controlling for the relationship between deer mouse abundance and ESAP. We found a reduction in deer mouse ESAP associated with the presence of voles, independent of vole abundance. A number of studies have documented that geographic locations which support a higher host diversity can be associated with reductions in pathogen prevalence by a hypothesized dilution effect. We suggest a dilution effect may also occur in a temporal dimension at sites where host richness fluctuates. Preservation of host diversity and optimization of environmental conditions which promote occurrence of ephemeral species, such as voles, may result in a decreased ESAP to hantaviruses among reservoir hosts. Our results may extend to other zoonotic infectious diseases.


Asunto(s)
Anticuerpos Antivirales/sangre , Arvicolinae/virología , Síndrome Pulmonar por Hantavirus/epidemiología , Peromyscus/virología , Enfermedades de los Roedores/epidemiología , Virus Sin Nombre/inmunología , Animales , Arvicolinae/sangre , Arvicolinae/inmunología , Femenino , Síndrome Pulmonar por Hantavirus/inmunología , Síndrome Pulmonar por Hantavirus/veterinaria , Masculino , Montana/epidemiología , Peromyscus/sangre , Peromyscus/inmunología , Dinámica Poblacional , Prevalencia , Enfermedades de los Roedores/inmunología , Virus Sin Nombre/aislamiento & purificación
13.
J Anim Ecol ; 79(2): 462-70, 2010 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-20015212

RESUMEN

1. Since Sin Nombre virus was discovered in the U.S. in 1993, longitudinal studies of the rodent reservoir host, the deer mouse (Peromyscus maniculatus) have demonstrated a qualitative correlation among mouse population dynamics and risk of hantavirus pulmonary syndrome (HPS) in humans, indicating the importance of understanding deer mouse population dynamics for evaluating risk of HPS. 2. Using capture-mark-recapture statistical methods on a 15-year data set from Montana, we estimated deer mouse survival, maturation and recruitment rates and tested the relative importance of seasonality, population density and local climate in explaining temporal variation in deer mouse demography. 3. From these estimates, we designed a population model to simulate deer mouse population dynamics given climatic variables and compared the model to observed patterns. 4. Month, precipitation 5 months previously, temperature 5 months previously and to a lesser extent precipitation and temperature in the current month, were important in determining deer mouse survival. Month, the sum of precipitation over the last 4 months, and the sum of the temperature over the last 4 months were important in determining recruitment rates. Survival was more important in determining the growth rate of the population than recruitment. 5. While climatic drivers appear to have a complex influence on dynamics, our forecasts were good. Our quantitative model may allow public health officials to better predict increased human risk from basic climatic data.


Asunto(s)
Reservorios de Enfermedades , Peromyscus/fisiología , Lluvia , Estaciones del Año , Temperatura , Animales , Ratones , Modelos Biológicos , Montana , Peromyscus/virología , Densidad de Población , Dinámica Poblacional , Virus Sin Nombre/fisiología , Análisis de Supervivencia
14.
J Environ Monit ; 12(11): 2048-55, 2010 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-20957286

RESUMEN

In a world of emerging and resurging infectious diseases, dominated by zoonoses, environmental monitoring plays a vital role in our understanding their dynamics and their spillover to humans. Here, we critically review the ecology, epidemiology and need for monitoring of a variety of directly transmitted (Sin Nombre virus, Avian Influenza) and vector-borne (Ross River virus, West Nile virus, Lyme disease, anaplasmosis and babesiosis) zoonoses. We focus on the valuable role that existing monitoring plays in the understanding of these zoonoses, the demands for new monitoring, and how improvements can be made to existing monitoring. We also identify the fruitful outcomes which would result from implementation of the monitoring demands we have highlighted. This review aims to promote improvements in our understanding of zoonoses, their management, and public health by encouraging discussion among researchers and public health officials.


Asunto(s)
Enfermedades Transmisibles/epidemiología , Brotes de Enfermedades/prevención & control , Monitoreo del Ambiente/métodos , Animales , Enfermedades Transmisibles/parasitología , Enfermedades Transmisibles/virología , Monitoreo Epidemiológico , Humanos , Salud Pública/métodos
15.
J Homosex ; 67(11): 1587-1602, 2020 Sep 18.
Artículo en Inglés | MEDLINE | ID: mdl-31006354

RESUMEN

Scholars have recently started to examine how minority stressors are associated with wellbeing outcomes among lesbian, gay, and bisexual (LGB) people. Such studies have examined mainly hedonic wellbeing, and those that have investigated eudaimonic wellbeing have tended to use composite measures. The present study draws from this literature to examine how minority stressors are associated with a key indicator of eudaimonic wellbeing: life meaning. Drawing from the minority stress model, we examined these associations using structural equation modeling among 266 LGB adults. Expectations of rejection and identity concealment, but not discrimination or internalized homophobia, had significant negative associations with life meaning. Discrimination had negative indirect associations with life meaning via expectations of rejection and concealment. Our results highlight the nuanced relations that exist between minority stressors and life meaning and highlight the need to move beyond composite measures of wellbeing. Implications for clinical practice and directions for research are discussed.


Asunto(s)
Felicidad , Minorías Sexuales y de Género/psicología , Estrés Psicológico , Adolescente , Adulto , Bisexualidad , Mecanismos de Defensa , Femenino , Homofobia , Homosexualidad Femenina , Humanos , Masculino , Persona de Mediana Edad , Grupos Minoritarios/psicología , Adulto Joven
16.
J Appl Psychol ; 105(12): 1382-1396, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33090858

RESUMEN

The authors assess levels and within-person changes in psychological well-being (i.e., depressive symptoms and life satisfaction) from before to during the COVID-19 pandemic for individuals in the United States, in general and by socioeconomic status (SES). The data is from 2 surveys of 1,143 adults from RAND Corporation's nationally representative American Life Panel, the first administered between April-June, 2019 and the second during the initial peak of the pandemic in the United States in April, 2020. Depressive symptoms during the pandemic were higher than population norms before the pandemic. Depressive symptoms increased from before to during COVID-19 and life satisfaction decreased. Individuals with higher education experienced a greater increase in depressive symptoms and a greater decrease in life satisfaction from before to during COVID-19 in comparison to those with lower education. Supplemental analysis illustrates that income had a curvilinear relationship with changes in well-being, such that individuals at the highest levels of income experienced a greater decrease in life satisfaction from before to during COVID-19 than individuals with lower levels of income. We draw on conservation of resources theory and the theory of fundamental social causes to examine four key mechanisms (perceived financial resources, perceived control, interpersonal resources, and COVID-19-related knowledge/news consumption) underlying the relationship between SES and well-being during COVID-19. These resources explained changes in well-being for the sample as a whole but did not provide insight into why individuals of higher education experienced a greater decline in well-being from before to during COVID-19. (PsycInfo Database Record (c) 2020 APA, all rights reserved).


Asunto(s)
COVID-19/psicología , Trastorno Depresivo/psicología , Encuestas Epidemiológicas/estadística & datos numéricos , Satisfacción Personal , Clase Social , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Escolaridad , Femenino , Encuestas Epidemiológicas/métodos , Humanos , Masculino , Persona de Mediana Edad , Pandemias , Estados Unidos
17.
J Homosex ; 66(2): 238-259, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-29072528

RESUMEN

The present study examined the link between discrimination and the three components of subjective wellbeing (positive and negative affect and life satisfaction) among a cisgender sample of lesbian, gay, and bisexual (LGB) adults. Specifically, we investigated internalized homonegativity and expectations of rejection as potential mediators of the links between discrimination and subjective wellbeing among a sample of 215 participants. Results from our structural equation model demonstrated a strong, positive direct link between discrimination and negative affect. Discrimination also had small, negative indirect effects on life satisfaction through our two mediators. Interestingly, neither discrimination nor our two mediators were related with positive affect, demonstrating the need for future research to uncover potential buffers of this link. Finally, our model evidenced configural, metric, and scalar invariance, suggesting that our model applies well for both women and men. Practical implications and future directions for research are discussed.


Asunto(s)
Bisexualidad/psicología , Minorías Sexuales y de Género/psicología , Discriminación Social , Estrés Psicológico , Adulto , Mecanismos de Defensa , Femenino , Identidad de Género , Humanos , Masculino , Factores Sexuales , Conducta Sexual , Adulto Joven
18.
Vector Borne Zoonotic Dis ; 7(3): 353-64, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17767405

RESUMEN

American hantaviruses cause a severe respiratory disease known as hantavirus pulmonary syndrome (HPS). In the United States, Sin Nombre virus (SNV), carried by the deer mouse ( Peromyscus maniculatus), is the etiologic agent in the majority of HPS cases. The relationship between deer mouse population density and SNV infection prevalence in deer mice is poorly understood. Our purpose was to clarify this relationship by demonstrating the existence of delayed-density-dependent prevalence of SNV infection in populations of wild deer mice. We also explored the relationship between SNV infection in deer mouse populations and the incidence of human HPS. The study population was 3,616 deer mice captured on 10 mark-recapture grids in Montana during May and September, 1994-2004. Using multivariate logistic regression analysis, we found a strong association between deer mouse population density in fall (September) and SNV antibody prevalence in deer mice the following spring (May). Other characteristics associated with SNV infection in deer mice in spring were: (1) presence of at least one infected deer mouse in the population the previous fall, (2) male gender, (3) adult age class, (4) presence of scars, (5) grassland and logged habitats, and (6) elevations below 1,300 m. There was a strong association between concurrently measured SNV antibody prevalence in deer mice and probable exposure of human HPS cases during the same time period. Human cases were more likely to occur during seasons when SNV antibody prevalence was at least 10% in deer mouse populations. These findings suggest that fall rodent population parameters could be used to help guide prevention efforts the following spring.


Asunto(s)
Anticuerpos Antivirales/sangre , Síndrome Pulmonar por Hantavirus/epidemiología , Síndrome Pulmonar por Hantavirus/inmunología , Peromyscus/virología , Virus Sin Nombre/fisiología , Animales , Femenino , Humanos , Modelos Logísticos , Masculino , Montana/epidemiología , Peromyscus/inmunología , Densidad de Población , Dinámica Poblacional , Prevalencia , Factores de Riesgo , Estaciones del Año , Virus Sin Nombre/inmunología , Virus Sin Nombre/aislamiento & purificación , Factores de Tiempo
19.
J Wildl Dis ; 43(1): 12-22, 2007 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-17347389

RESUMEN

Sin Nombre virus (SNV), hosted by the deer mouse (Peromyscus maniculatus), is the principal cause of hantavirus pulmonary syndrome (HPS) in North America. To improve our understanding of factors that contribute to the occurrence of HPS, we conducted an extensive field study of the characteristics of newly infected (as determined by recent acquisition of antibody) deer mice and the temporal pattern of antibody acquisition (seroconversion) from 1994 through 2004 in Montana, USA. We sampled 6,584 individual deer mice, of which 2,747 were captured over multiple trapping periods. Among these 2,747 deer mice, we detected 171 instances of seroconversion. There was no relationship between seroconversion and the acquisition of scars. However, recently infected Montana deer mice were more likely to be older, more likely to be males, and more likely to be in breeding condition. In addition, recently infected male deer mice gained less weight over the 1-mo period following seroconversion than did those that did not acquire antibody, suggesting that SNV infection may have negatively impacted the health of infected rodents. Incidence was highly variable among years, and timing of infections was primarily associated with the breeding season (generally early spring through late fall).


Asunto(s)
Anticuerpos Antivirales/sangre , Síndrome Pulmonar por Hantavirus/veterinaria , Peromyscus/virología , Enfermedades de los Roedores/epidemiología , Virus Sin Nombre/inmunología , Factores de Edad , Animales , Cruzamiento , Femenino , Síndrome Pulmonar por Hantavirus/epidemiología , Incidencia , Masculino , Montana/epidemiología , Estaciones del Año , Estudios Seroepidemiológicos , Factores Sexuales
20.
J Wildl Dis ; 43(1): 1-11, 2007 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-17347388

RESUMEN

We used long-term data collected for up to 10 yr (1994-2004) at 23 trapping arrays (i.e., webs and grids) in Arizona, Colorado, Montana, and New Mexico to examine demographic factors known or suspected to be associated with risk of infection with Sin Nombre virus (SNV) in its natural host, the deer mouse (Peromyscus maniculatus). Gender, age (mass), wounds or scars, season, and local relative population densities were statistically associated with the period prevalence of antibody (used as a marker of infection) to SNV in host populations. Nevertheless, antibody prevalence and some of the risk factors associated with antibody prevalence, such as relative population density, gender bias, and prevalence of wounding, varied significantly among sites and even between nearby trapping arrays at a single site. This suggests that local microsite-specific differences play an important role in determining relative risk of infection by SNV in rodents and, consequently, in humans. Deer mouse relative population density varied among sites and was positively and statistically associated with infection prevalence, an association that researchers conducting shorter-term studies failed to demonstrate. Both wounding and antibody prevalence increased with mass class in both males and females; this increase was much more pronounced in males than in females and wounding was more frequent in adult males than in adult females. Prevalence of wounding was greatest among seropositive deer mice, regardless of mass class, but many deer mice without detectable wounds or scars eventually became infected. Many of these patterns, which will be useful in the development of predictive models of disease risk to humans, were only detected through the application of data collected over a long (10-yr) period and with abundant replication.


Asunto(s)
Anticuerpos Antivirales/sangre , Síndrome Pulmonar por Hantavirus/veterinaria , Peromyscus , Enfermedades de los Roedores/epidemiología , Virus Sin Nombre/inmunología , Animales , Animales Salvajes/virología , Femenino , Síndrome Pulmonar por Hantavirus/epidemiología , Masculino , Densidad de Población , Prevalencia , Factores de Riesgo , Estaciones del Año , Estudios Seroepidemiológicos , Factores Sexuales , Sudoeste de Estados Unidos/epidemiología , Heridas y Lesiones/complicaciones , Heridas y Lesiones/epidemiología , Heridas y Lesiones/veterinaria
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