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1.

RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis.

Rheinemann, Lara; Downhour, Diane Miller; Bredbenner, Kate; Mercenne, Gaelle; Davenport, Kristen A; Schmitt, Phuong Tieu; Necessary, Christina R; McCullough, John; Schmitt, Anthony P; Simon, Sanford M; Sundquist, Wesley I; Elde, Nels C.

Cell ; 184(21): 5419-5431.e16, 2021 10 14.

Artículo en Inglés | MEDLINE | ID: mdl-34597582

2.

Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus.

Rice, Marlen C; Janik, Andrew J; Elde, Nels C; Gagnon, James A; Balla, Keir M.

PLoS Biol ; 22(5): e3002606, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38814944

3.

Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses.

Elde, Nels C; Child, Stephanie J; Eickbush, Michael T; Kitzman, Jacob O; Rogers, Kelsey S; Shendure, Jay; Geballe, Adam P; Malik, Harmit S.

Cell ; 150(4): 831-41, 2012 Aug 17.

Artículo en Inglés | MEDLINE | ID: mdl-22901812

4.

Recurrent viral capture of cellular phosphodiesterases that antagonize OAS-RNase L.

Goldstein, Stephen A; Elde, Nels C.

Proc Natl Acad Sci U S A ; 121(5): e2312691121, 2024 Jan 30.

Artículo en Inglés | MEDLINE | ID: mdl-38277437

5.

Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network.

Sorouri, Mahsa; Chang, Tyron; Jesudhasan, Palmy; Pinkham, Chelsea; Elde, Nels C; Hancks, Dustin C.

PLoS Biol ; 18(12): e3001045, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33370271

6.

Regulatory activities of transposable elements: from conflicts to benefits.

Chuong, Edward B; Elde, Nels C; Feschotte, Cédric.

Nat Rev Genet ; 18(2): 71-86, 2017 02.

Artículo en Inglés | MEDLINE | ID: mdl-27867194

7.

Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.

Barber, Matthew F; Kronenberg, Zev; Yandell, Mark; Elde, Nels C.

PLoS Genet ; 12(5): e1006063, 2016 05.

Artículo en Inglés | MEDLINE | ID: mdl-27203426

8.

Disruption of promoter memory by synthesis of a long noncoding RNA.

Yu, Yaxin; Yarrington, Robert M; Chuong, Edward B; Elde, Nels C; Stillman, David J.

Proc Natl Acad Sci U S A ; 113(34): 9575-80, 2016 08 23.

Artículo en Inglés | MEDLINE | ID: mdl-27506791

9.

Buried Treasure: Evolutionary Perspectives on Microbial Iron Piracy.

Barber, Matthew F; Elde, Nels C.

Trends Genet ; 31(11): 627-636, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26431675

10.

Emergence of a Viral RNA Polymerase Variant during Gene Copy Number Amplification Promotes Rapid Evolution of Vaccinia Virus.

Cone, Kelsey R; Kronenberg, Zev N; Yandell, Mark; Elde, Nels C.

J Virol ; 91(4)2017 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-27928012

11.

Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.

Hancks, Dustin C; Hartley, Melissa K; Hagan, Celia; Clark, Nathan L; Elde, Nels C.

PLoS Genet ; 11(5): e1005203, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25942676

12.

Baculovirus protein PK2 subverts eIF2α kinase function by mimicry of its kinase domain C-lobe.

Li, John J; Cao, Chune; Fixsen, Sarah M; Young, Janet M; Ono, Chikako; Bando, Hisanori; Elde, Nels C; Katsuma, Susumu; Dever, Thomas E; Sicheri, Frank.

Proc Natl Acad Sci U S A ; 112(32): E4364-73, 2015 Aug 11.

Artículo en Inglés | MEDLINE | ID: mdl-26216977

13.

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.

Orzalli, Megan H; Broekema, Nicole M; Diner, Benjamin A; Hancks, Dustin C; Elde, Nels C; Cristea, Ileana M; Knipe, David M.

Proc Natl Acad Sci U S A ; 112(14): E1773-81, 2015 Apr 07.

Artículo en Inglés | MEDLINE | ID: mdl-25831530

14.

Wham: Identifying Structural Variants of Biological Consequence.

Kronenberg, Zev N; Osborne, Edward J; Cone, Kelsey R; Kennedy, Brett J; Domyan, Eric T; Shapiro, Michael D; Elde, Nels C; Yandell, Mark.

PLoS Comput Biol ; 11(12): e1004572, 2015 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-26625158

15.

Protein kinase R reveals an evolutionary model for defeating viral mimicry.

Elde, Nels C; Child, Stephanie J; Geballe, Adam P; Malik, Harmit S.

Nature ; 457(7228): 485-9, 2009 Jan 22.

Artículo en Inglés | MEDLINE | ID: mdl-19043403

16.

Evolutionary biology: Mimicry all the way down.

Barber, Matthew F; Elde, Nels C.

Nature ; 501(7465): 38-9, 2013 Sep 05.

Artículo en Inglés | MEDLINE | ID: mdl-24005409

17.

Hidden evolutionary constraints dictate the retention of coronavirus accessory genes.

Goldstein, Stephen A; Feeley, Teagan M; Babler, Kristina M; Hilbert, Zoë A; Downhour, Diane M; Moshiri, Niema; Elde, Nels C.

bioRxiv ; 2024 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-37873270

18.

Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L.

Goldstein, Stephen A; Elde, Nels C.

bioRxiv ; 2023 Sep 14.

Artículo en Inglés | MEDLINE | ID: mdl-37745432

19.

Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus.

Rice, Marlen C; Elde, Nels C; Gagnon, James A; Balla, Keir M.

bioRxiv ; 2023 Aug 28.

Artículo en Inglés | MEDLINE | ID: mdl-37693489

20.

Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity.

Boys, Ian N; Johnson, Alex G; Quinlan, Meghan R; Kranzusch, Philip J; Elde, Nels C.

Cell Rep ; 42(8): 112878, 2023 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-37494187

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RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis.

Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus.

Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses.

Recurrent viral capture of cellular phosphodiesterases that antagonize OAS-RNase L.

Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network.

Regulatory activities of transposable elements: from conflicts to benefits.

Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.

Disruption of promoter memory by synthesis of a long noncoding RNA.

Buried Treasure: Evolutionary Perspectives on Microbial Iron Piracy.

Emergence of a Viral RNA Polymerase Variant during Gene Copy Number Amplification Promotes Rapid Evolution of Vaccinia Virus.

Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.

Baculovirus protein PK2 subverts eIF2α kinase function by mimicry of its kinase domain C-lobe.

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.

Wham: Identifying Structural Variants of Biological Consequence.

Protein kinase R reveals an evolutionary model for defeating viral mimicry.

Evolutionary biology: Mimicry all the way down.

Hidden evolutionary constraints dictate the retention of coronavirus accessory genes.

Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L.

Microbe transmission from pet shop to lab-reared zebrafish reveals a pathogenic birnavirus.

Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity.