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1.

EBV and MS: The evidence is growing stronger.

Farrell, Paul J.

Cell ; 186(26): 5675-5676, 2023 12 21.

Artículo en Inglés | MEDLINE | ID: mdl-38134873

2.

Epstein-Barr Virus Genome Deletions in Epstein-Barr Virus-Positive T/NK Cell Lymphoproliferative Diseases.

Wongwiwat, Wiyada; Fournier, Benjamin; Bassano, Irene; Bayoumy, Amr; Elgueta Karstegl, Claudio; Styles, Christine; Bridges, Ray; Lenoir, Christelle; BoutBoul, David; Moshous, Despina; Neven, Bénédicte; Kanda, Teru; Morgan, Rhys G; White, Robert E; Latour, Sylvain; Farrell, Paul J.

J Virol ; 96(12): e0039422, 2022 06 22.

Artículo en Inglés | MEDLINE | ID: mdl-35612313

3.

EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes.

Su, Chenhe; Lu, Fang; Soldan, Samantha S; Lamontagne, R Jason; Tang, Hsin-Yao; Napoletani, Giorgia; Farrell, Paul J; Tempera, Italo; Kossenkov, Andrew V; Lieberman, Paul M.

PLoS Pathog ; 17(8): e1009834, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-34352044

4.

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection.

Romero-Masters, James C; Huebner, Shane M; Ohashi, Makoto; Bristol, Jillian A; Benner, Bayleigh E; Barlow, Elizabeth A; Turk, Gail L; Nelson, Scott E; Baiu, Dana C; Van Sciver, Nicholas; Ranheim, Erik A; Gumperz, Jenny; Sherer, Nathan M; Farrell, Paul J; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 16(2): e1008365, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-32059024

5.

Epstein-Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV.

Venturini, Cristina; Houldcroft, Charlotte J; Lazareva, Arina; Wegner, Fanny; Morfopoulou, Sofia; Amrolia, Persis J; Golwala, Zainab; Rao, Anupama; Marks, Stephen D; Simmonds, Jacob; Yoshikawa, Tetsushi; Farrell, Paul J; Cohen, Jeffrey I; Worth, Austen J; Breuer, Judith.

Br J Haematol ; 195(2): 249-255, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34431085

6.

Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity.

Ponnusamy, Rajesh; Khatri, Ritika; Correia, Paulo B; Wood, C David; Mancini, Erika J; Farrell, Paul J; West, Michelle J.

PLoS Pathog ; 15(7): e1007458, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31283782

7.

Requirement for PRC1 subunit BMI1 in host gene activation by Epstein-Barr virus protein EBNA3C.

Paschos, Kostas; Bazot, Quentin; Lees, Jonathan; Farrell, Paul J; Allday, Martin J.

Nucleic Acids Res ; 47(6): 2807-2821, 2019 04 08.

Artículo en Inglés | MEDLINE | ID: mdl-30649516

8.

A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection.

Bristol, Jillian A; Djavadian, Reza; Albright, Emily R; Coleman, Carrie B; Ohashi, Makoto; Hayes, Mitchell; Romero-Masters, James C; Barlow, Elizabeth A; Farrell, Paul J; Rochford, Rosemary; Kalejta, Robert F; Johannsen, Eric C; Kenney, Shannon C.

PLoS Pathog ; 14(7): e1007179, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-30052684

9.

Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases.

Correia, Samantha; Bridges, Ray; Wegner, Fanny; Venturini, Cristina; Palser, Anne; Middeldorp, Jaap M; Cohen, Jeffrey I; Lorenzetti, Mario A; Bassano, Irene; White, Robert E; Kellam, Paul; Breuer, Judith; Farrell, Paul J.

J Virol ; 92(22)2018 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-30111570

10.

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation.

Brady, Gareth; Haas, Darya A; Farrell, Paul J; Pichlmair, Andreas; Bowie, Andrew G.

J Virol ; 91(15)2017 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-28490597

11.

Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA.

Correia, Samantha; Palser, Anne; Elgueta Karstegl, Claudio; Middeldorp, Jaap M; Ramayanti, Octavia; Cohen, Jeffrey I; Hildesheim, Allan; Fellner, Maria Dolores; Wiels, Joelle; White, Robert E; Kellam, Paul; Farrell, Paul J.

J Virol ; 91(15)2017 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-28515295

12.

Iron metabolism as a novel therapeutic target.

Farrell, Paul J.

Blood ; 138(22): 2155-2156, 2021 12 02.

Artículo en Inglés | MEDLINE | ID: mdl-34854879

13.

RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.

Gunnell, Andrea; Webb, Helen M; Wood, C David; McClellan, Michael J; Wichaidit, Billy; Kempkes, Bettina; Jenner, Richard G; Osborne, Cameron; Farrell, Paul J; West, Michelle J.

Nucleic Acids Res ; 44(10): 4636-50, 2016 06 02.

Artículo en Inglés | MEDLINE | ID: mdl-26883634

14.

Roles of RUNX in B Cell Immortalisation.

West, Michelle J; Farrell, Paul J.

Adv Exp Med Biol ; 962: 283-298, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28299664

15.

Dimerization of matrix protein is required for budding of respiratory syncytial virus.

Förster, Andreas; Maertens, Goedele N; Farrell, Paul J; Bajorek, Monika.

J Virol ; 89(8): 4624-35, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25673702

16.

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-B Activation by Targeting p65 for Degradation.

Brady, Gareth; Haas, Darya A; Farrell, Paul J; Pichlmair, Andreas; Bowie, Andrew G.

J Virol ; 89(16): 8406-15, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-26041281

17.

Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice.

Gregorovic, Goran; Boulden, Elizabeth A; Bosshard, Rachel; Elgueta Karstegl, Claudio; Skalsky, Rebecca; Cullen, Bryan R; Gujer, Cornelia; Rämer, Patrick; Münz, Christian; Farrell, Paul J.

J Virol ; 89(22): 11711-4, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26339045

18.

Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.

Palser, Anne L; Grayson, Nicholas E; White, Robert E; Corton, Craig; Correia, Samantha; Ba Abdullah, Mohammed M; Watson, Simon J; Cotten, Matthew; Arrand, John R; Murray, Paul G; Allday, Martin J; Rickinson, Alan B; Young, Lawrence S; Farrell, Paul J; Kellam, Paul.

J Virol ; 89(10): 5222-37, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25787276

19.

Epstein-Barr Virus Strain Variation.

Farrell, Paul J.

Curr Top Microbiol Immunol ; 390(Pt 1): 45-69, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26424643

20.

A single amino acid in EBNA-2 determines superior B lymphoblastoid cell line growth maintenance by Epstein-Barr virus type 1 EBNA-2.

Tzellos, Stelios; Correia, Paulo B; Karstegl, Claudio Elgueta; Cancian, Laila; Cano-Flanagan, Julian; McClellan, Michael J; West, Michelle J; Farrell, Paul J.

J Virol ; 88(16): 8743-53, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24850736

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EBV and MS: The evidence is growing stronger.

Epstein-Barr Virus Genome Deletions in Epstein-Barr Virus-Positive T/NK Cell Lymphoproliferative Diseases.

EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes.

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection.

Epstein-Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV.

Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity.

Requirement for PRC1 subunit BMI1 in host gene activation by Epstein-Barr virus protein EBNA3C.

A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection.

Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases.

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation.

Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA.

Iron metabolism as a novel therapeutic target.

RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.

Roles of RUNX in B Cell Immortalisation.

Dimerization of matrix protein is required for budding of respiratory syncytial virus.

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-B Activation by Targeting p65 for Degradation.

Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice.

Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.

Epstein-Barr Virus Strain Variation.

A single amino acid in EBNA-2 determines superior B lymphoblastoid cell line growth maintenance by Epstein-Barr virus type 1 EBNA-2.