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Anticancer Res ; 37(2): 849-852, 2017 02.
Artículo en Inglés | MEDLINE | ID: mdl-28179341

RESUMEN

Waste collectors collect, transport, and process the garbage produced by people living in the city. Nowadays, this activity requires special attention due to the environmental impact of garbage and its potential consequences on human health. The aim of this study was to evaluate potential cytotoxic and mutagenic effects of garbage collection on waste collectors. For this purpose, a total of 47 male waste collectors aged from 24 to 53 years were included in the experimental group. A total of 30 men matched by age were used as the control group. Cytotoxicity and mutagenicity were analyzed by micronucleus test in buccal mucosaI cells. No statistically significant difference (p>0.05) in the frequency of micronuclei was detected in the waste collectors when compared to controls. Nevertheless, higher frequencies of karyolysis and pyknosis (p<0.05) were detected in buccal mucosaI cells from waste collectors when compared to matched controls. Taken together, our results indicate that waste collectors comprise an at-risk group as a result of increased cytotoxicity apparent from buccal mucosa cells.


Asunto(s)
Análisis Citogenético/métodos , Monitoreo del Ambiente/métodos , Mucosa Bucal/metabolismo , Salud Laboral/estadística & datos numéricos , Residuos Sólidos/análisis , Adulto , Núcleo Celular/efectos de los fármacos , Núcleo Celular/genética , Supervivencia Celular/efectos de los fármacos , Sustancias Peligrosas/análisis , Sustancias Peligrosas/farmacología , Humanos , Masculino , Micronúcleos con Defecto Cromosómico/efectos de los fármacos , Pruebas de Micronúcleos/métodos , Persona de Mediana Edad , Mucosa Bucal/citología , Exposición Profesional/análisis , Salud Laboral/normas , Adulto Joven
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