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J Control Release ; 333: 258-268, 2021 05 10.
Artículo en Inglés | MEDLINE | ID: mdl-33766691

RESUMEN

Drug releasing particles are valued for their ability to deliver therapeutics to targeted locations and for their controllable release patterns. The development of microfluidic technologies, which are designed specifically to manipulate small amounts of fluids, to manufacture particles for drug delivery applications reflects a recent trend due to the advantages they confer in terms of control over particle size and material composition. This review takes a comprehensive look at the different types of microfluidic devices used to fabricate such particles from different types of biomaterials, and at how the on-chip features enable the production of particles with different types of properties. The review concludes by suggesting avenues for future work that will enable these technologies to fulfill their potential and be used in industrial settings for the manufacture of drug releasing particles with unique capabilities.


Asunto(s)
Microfluídica , Preparaciones Farmacéuticas , Materiales Biocompatibles , Sistemas de Liberación de Medicamentos , Tamaño de la Partícula
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