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1.
Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity.
J Biol Chem
; 298(2): 101556, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34973338
2.
Inhibition of 5-lipoxygenase selectively triggers disruption of c-Myc signaling in prostate cancer cells.
J Biol Chem
; 290(8): 4994-5006, 2015 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25540201
3.
MK591 (Quiflapon), a 5-lipoxygenase inhibitor, kills pancreatic cancer cells via downregulation of protein kinase C-epsilon.
Front Oncol
; 14: 1387535, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38746674
4.
Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells.
Mol Cancer Ther
; 22(3): 381-392, 2023 03 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36805730
5.
Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon.
Biochim Biophys Acta
; 1813(12): 2108-17, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21824498
6.
Pharmacological and genetic targeting of 5-lipoxygenase interrupts c-Myc oncogenic signaling and kills enzalutamide-resistant prostate cancer cells via apoptosis.
Sci Rep
; 10(1): 6649, 2020 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32313135
7.
Inhibition of 5-lipoxygenase downregulates stemness and kills prostate cancer stem cells by triggering apoptosis via activation of c-Jun N-terminal kinase.
Oncotarget
; 10(4): 424-436, 2019 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30728896
8.
Wedelolactone, an Anti-inflammatory Botanical, Interrupts c-Myc Oncogenic Signaling and Synergizes with Enzalutamide to Induce Apoptosis in Prostate Cancer Cells.
Mol Cancer Ther
; 15(11): 2791-2801, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27474149
9.
MK591, a second generation leukotriene biosynthesis inhibitor, prevents invasion and induces apoptosis in the bone-invading C4-2B human prostate cancer cells: implications for the treatment of castration-resistant, bone-metastatic prostate cancer.
PLoS One
; 10(4): e0122805, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25875826
10.
OXER1, a G protein-coupled oxoeicosatetraenoid receptor, mediates the survival-promoting effects of arachidonate 5-lipoxygenase in prostate cancer cells.
Cancer Lett
; 336(1): 185-95, 2013 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-23643940
11.
Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt.
Int J Oncol
; 41(6): 2191-9, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23076676
12.
MK591, a leukotriene biosynthesis inhibitor, induces apoptosis in prostate cancer cells: synergistic action with LY294002, an inhibitor of phosphatidylinositol 3'-kinase.
Cancer Lett
; 291(2): 167-76, 2010 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-19906484
13.
Selenite triggers rapid transcriptional activation of p53, and p53-mediated apoptosis in prostate cancer cells: Implication for the treatment of early-stage prostate cancer.
Int J Oncol
; 36(6): 1419-28, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20428765
14.
Molecular mechanisms of prostate cancer cell death triggered by inhibition of arachidonate 5-lipoxygenase: involvement of Fas death receptor-mediated signals.
Adv Exp Med Biol
; 507: 415-20, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12664619
15.
Expression of 5-oxoETE receptor in prostate cancer cells: critical role in survival.
Biochem Biophys Res Commun
; 339(1): 93-8, 2006 Jan 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-16289380
16.
Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase.
Biochem Biophys Res Commun
; 315(3): 624-35, 2004 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-14975747
17.
Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase.
Biochem Biophys Res Commun
; 307(2): 342-9, 2003 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-12859962
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