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1.

Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid.

Garcia-Pavia, Pablo; Aus dem Siepen, Fabian; Donal, Erwan; Lairez, Olivier; van der Meer, Peter; Kristen, Arnt V; Mercuri, Michele F; Michalon, Aubin; Frost, Robert J A; Grimm, Jan; Nitsch, Roger M; Hock, Christoph; Kahr, Peter C; Damy, Thibaud.

N Engl J Med ; 389(3): 239-250, 2023 Jul 20.

Artículo en Inglés | MEDLINE | ID: mdl-37212440

2.

Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells.

Bakht, Martin K; Hayward, John J; Shahbazi-Raz, Farsheed; Skubal, Magdalena; Tamura, Ryo; Stringer, Keith F; Meister, Daniel; Venkadakrishnan, Varadha Balaji; Xue, Hui; Pillon, Adam; Stover, Mathew; Tronchin, Adam; Fifield, Bre-Anne; Mader, Lavleen; Ku, Sheng-Yu; Cheon, Gi Jeong; Kang, Keon Wook; Wang, Yuzhuo; Dong, Xuesen; Beltran, Himisha; Grimm, Jan; Porter, Lisa A; Trant, John F.

Proc Natl Acad Sci U S A ; 119(4)2022 01 25.

Artículo en Inglés | MEDLINE | ID: mdl-35064078

3.

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.

Jambeau, Melanie; Meyer, Kevin D; Hruska-Plochan, Marian; Tabet, Ricardos; Lee, Chao-Zong; Ray-Soni, Ananya; Aguilar, Corey; Savage, Kitty; Mishra, Nibha; Cavegn, Nicole; Borter, Petra; Lin, Chun-Chia; Jansen-West, Karen R; Jiang, Jie; Freyermuth, Fernande; Li, Nan; De Rossi, Pierre; Pérez-Berlanga, Manuela; Jiang, Xin; Daughrity, Lilian M; Pereira, João; Narayanan, Sarav; Gu, Yuanzheng; Dhokai, Shekhar; Dalkilic-Liddle, Isin; Maniecka, Zuzanna; Weber, Julien; Workman, Michael; McAlonis-Downes, Melissa; Berezovski, Eugene; Zhang, Yong-Jie; Berry, James; Wainger, Brian J; Kankel, Mark W; Rushe, Mia; Hock, Christoph; Nitsch, Roger M; Cleveland, Don W; Petrucelli, Leonard; Gendron, Tania F; Montrasio, Fabio; Grimm, Jan; Polymenidou, Magdalini; Lagier-Tourenne, Clotilde.

Proc Natl Acad Sci U S A ; 119(49): e2123487119, 2022 12 06.

Artículo en Inglés | MEDLINE | ID: mdl-36454749

4.

Current clinical applications of Cerenkov luminescence for intraoperative molecular imaging.

Boykoff, Natalie; Grimm, Jan.

Eur J Nucl Med Mol Imaging ; 2024 Jan 20.

Artículo en Inglés | MEDLINE | ID: mdl-38243119

5.

Surgical radioguidance with beta-emitting radionuclides; challenges and possibilities: A position paper by the EANM.

Fragoso Costa, Pedro; Shi, Kuangyu; Holm, Soren; Vidal-Sicart, Sergi; Kracmerova, Tereza; Tosi, Giovanni; Grimm, Jan; Visvikis, Dimitris; Knapp, Wolfram H; Gnanasegaran, Gopinath; van Leeuwen, Fijs W B.

Eur J Nucl Med Mol Imaging ; 2024 Jan 08.

Artículo en Inglés | MEDLINE | ID: mdl-38189911

6.

Addendum: The antibody aducanumab reduces Aß plaques in Alzheimer's disease.

Sevigny, Jeff; Chiao, Ping; Bussière, Thierry; Weinreb, Paul H; Williams, Leslie; Maier, Marcel; Dunstan, Robert; Salloway, Stephen; Chen, Tianle; Ling, Yan; O'Gorman, John; Qian, Fang; Arastu, Mahin; Li, Mingwei; Chollate, Sowmya; Brennan, Melanie S; Quintero-Monzon, Omar; Scannevin, Robert H; Arnold, H Moore; Engber, Thomas; Rhodes, Kenneth; Ferrero, James; Hang, Yaming; Mikulskis, Alvydas; Grimm, Jan; Hock, Christoph; Nitsch, Roger M; Sandrock, Alfred.

Nature ; 546(7659): 564, 2017 06 21.

Artículo en Inglés | MEDLINE | ID: mdl-28640269

7.

The antibody aducanumab reduces Aß plaques in Alzheimer's disease.

Sevigny, Jeff; Chiao, Ping; Bussière, Thierry; Weinreb, Paul H; Williams, Leslie; Maier, Marcel; Dunstan, Robert; Salloway, Stephen; Chen, Tianle; Ling, Yan; O'Gorman, John; Qian, Fang; Arastu, Mahin; Li, Mingwei; Chollate, Sowmya; Brennan, Melanie S; Quintero-Monzon, Omar; Scannevin, Robert H; Arnold, H Moore; Engber, Thomas; Rhodes, Kenneth; Ferrero, James; Hang, Yaming; Mikulskis, Alvydas; Grimm, Jan; Hock, Christoph; Nitsch, Roger M; Sandrock, Alfred.

Nature ; 537(7618): 50-6, 2016 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-27582220

8.

Ultrasmall Downconverting Nanoparticle for Enhanced Cerenkov Imaging.

Zhang, Qize; Pratt, Edwin C; Tamura, Ryo; Ogirala, Anuja; Hsu, Hsiao-Ting; Farahmand, Nasim; O'Brien, Stephen; Grimm, Jan.

Nano Lett ; 21(10): 4217-4224, 2021 05 26.

Artículo en Inglés | MEDLINE | ID: mdl-33950695

9.

Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.

Weihofen, Andreas; Liu, YuTing; Arndt, Joseph W; Huy, Christian; Quan, Chao; Smith, Benjamin A; Baeriswyl, Jean-Luc; Cavegn, Nicole; Senn, Luzia; Su, Lihe; Marsh, Galina; Auluck, Pavan K; Montrasio, Fabio; Nitsch, Roger M; Hirst, Warren D; Cedarbaum, Jesse M; Pepinsky, R Blake; Grimm, Jan; Weinreb, Paul H.

Neurobiol Dis ; 124: 276-288, 2019 04.

Artículo en Inglés | MEDLINE | ID: mdl-30381260

10.

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.

Nobuhara, Chloe K; DeVos, Sarah L; Commins, Caitlin; Wegmann, Susanne; Moore, Benjamin D; Roe, Allyson D; Costantino, Isabel; Frosch, Matthew P; Pitstick, Rose; Carlson, George A; Hock, Christoph; Nitsch, Roger M; Montrasio, Fabio; Grimm, Jan; Cheung, Anne E; Dunah, Anthone W; Wittmann, Marion; Bussiere, Thierry; Weinreb, Paul H; Hyman, Bradley T; Takeda, Shuko.

Am J Pathol ; 187(6): 1399-1412, 2017 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-28408124

11.

Targetable Clinical Nanoparticles for Precision Cancer Therapy Based on Disease-Specific Molecular Inflection Points.

Kaittanis, Charalambos; Bolaender, Alexander; Yoo, Barney; Shah, Nilesh; Ouerfelli, Ouathek; Grimm, Jan.

Nano Lett ; 17(11): 7160-7168, 2017 11 08.

Artículo en Inglés | MEDLINE | ID: mdl-29035540

12.

Near-Infrared Quantum Dot and ⁸⁹Zr Dual-Labeled Nanoparticles for in Vivo Cerenkov Imaging.

Zhao, Yiming; Shaffer, Travis M; Das, Sudeep; Pérez-Medina, Carlos; Mulder, Willem J M; Grimm, Jan.

Bioconjug Chem ; 28(2): 600-608, 2017 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-28026929

13.

Stable Radiolabeling of Sulfur-Functionalized Silica Nanoparticles with Copper-64.

Shaffer, Travis M; Harmsen, Stefan; Khwaja, Emaad; Kircher, Moritz F; Drain, Charles Michael; Grimm, Jan.

Nano Lett ; 16(9): 5601-4, 2016 09 14.

Artículo en Inglés | MEDLINE | ID: mdl-27464258

14.

Lymph Node Micrometastases and In-Transit Metastases from Melanoma: In Vivo Detection with Multispectral Optoacoustic Imaging in a Mouse Model.

Neuschmelting, Volker; Lockau, Hannah; Ntziachristos, Vasilis; Grimm, Jan; Kircher, Moritz F.

Radiology ; 280(1): 137-50, 2016 07.

Artículo en Inglés | MEDLINE | ID: mdl-27144537

15.

Multifunctional MRI/PET Nanobeacons Derived from the in Situ Self-Assembly of Translational Polymers and Clinical Cargo through Coalescent Intermolecular Forces.

Kaittanis, Charalambos; Shaffer, Travis M; Bolaender, Alexander; Appelbaum, Zachary; Appelbaum, Jeremy; Chiosis, Gabriela; Grimm, Jan.

Nano Lett ; 15(12): 8032-43, 2015 Dec 09.

Artículo en Inglés | MEDLINE | ID: mdl-26540670

16.

Silica nanoparticles as substrates for chelator-free labeling of oxophilic radioisotopes.

Shaffer, Travis M; Wall, Matthew A; Harmsen, Stefan; Longo, Valerie A; Drain, Charles Michael; Kircher, Moritz F; Grimm, Jan.

Nano Lett ; 15(2): 864-8, 2015 Feb 11.

Artículo en Inglés | MEDLINE | ID: mdl-25559467

17.

Molecular imaging of prostate cancer: translating molecular biology approaches into the clinical realm.

Vargas, Hebert Alberto; Grimm, Jan; F Donati, Olivio; Sala, Evis; Hricak, Hedvig.

Eur Radiol ; 25(5): 1294-302, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25693661

18.

Insights Into Drug Development Using Nanotechnology.

Grimm, Jan.

Clin Adv Hematol Oncol ; 18(7): 379-381, 2020 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-32903248

19.

Nanoparticles for imaging: top or flop?

Kiessling, Fabian; Mertens, Marianne E; Grimm, Jan; Lammers, Twan.

Radiology ; 273(1): 10-28, 2014 10.

Artículo en Inglés | MEDLINE | ID: mdl-25247562

20.

Molecular imaging using nanoparticle quenchers of Cerenkov luminescence.

Thorek, Daniel L J; Das, Sudeep; Grimm, Jan.

Small ; 10(18): 3729-34, 2014 Sep 24.

Artículo en Inglés | MEDLINE | ID: mdl-24861843

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