Detalles de la búsqueda
1.
LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of the Anti-EL (Endothelial Lipase) Antibody MEDI5884 in Patients With Stable Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
; 41(12): 3005-3014, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34706556
2.
Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice.
Mol Cell Proteomics
; 19(6): 971-993, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32265294
3.
Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia.
J Proteome Res
; 18(9): 3245-3258, 2019 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31317746
4.
Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Receptor Signaling.
J Biol Chem
; 292(5): 1925-1933, 2017 02 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27994053
5.
A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice.
Hepatology
; 65(3): 950-968, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27880981
6.
Pancreatic beta cells in very old mice retain capacity for compensatory proliferation.
J Biol Chem
; 287(33): 27407-14, 2012 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-22740691
7.
Glucose and aging control the quiescence period that follows pancreatic beta cell replication.
Development
; 137(19): 3205-13, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20823063
8.
Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation.
Pharmaceutics
; 15(10)2023 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37896196
9.
Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity.
Diabetes Care
; 46(5): 985-992, 2023 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36809463
10.
High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity.
J Am Heart Assoc
; 12(3): e8145, 2023 02 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36695299
11.
Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans.
J Biol Chem
; 286(21): 19118-26, 2011 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21454522
12.
Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.
J Biol Chem
; 286(45): 39560-72, 2011 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21921030
13.
Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics.
Am J Physiol Endocrinol Metab
; 302(1): E87-E102, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21952036
14.
Mutational analysis of allosteric activation and inhibition of glucokinase.
Biochem J
; 440(2): 203-15, 2011 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21831042
15.
The prevalence of low muscle mass associated with obesity in the USA.
Skelet Muscle
; 12(1): 26, 2022 12 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36539856
16.
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries.
Mol Metab
; 55: 101392, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34781035
17.
Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity.
Bioorg Med Chem Lett
; 21(7): 1933-6, 2011 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21388809
18.
Research and development of glucokinase activators for diabetes therapy: theoretical and practical aspects.
Handb Exp Pharmacol
; (203): 357-401, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21484579
19.
Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization.
PLoS One
; 16(6): e0252426, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34086718
20.
Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease.
Sci Rep
; 11(1): 22521, 2021 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34795324