RESUMEN
Objetivo: Comparar el efecto del tratamiento con hierro oral e intravenoso en la anemia ferropenica posparto. Material y método Trece mujeres con hemoglobina 7-10g/dl y ferritina < 15µg/l a las 24h posparto fueron aleatorizadas en 2 grupos, uno recibió hierro intravenoso (2 dosis de 200mg de hierro sacarosa) los días 2 y 4 tras el parto, y el otro el tratamiento estandar, 200mg de sulfato ferroso oral 2 veces/dia durante 6 semanas. Resultados En el grupo del hierro intravenoso los valores de ferritina el día 7 fueron superiores (p=0,002) (..) (AU)
Objective: To compare the effect of treatment with oral and intravenous iron in postpartumiron deficiency anemia. Material and method: Thirteen women with hemoglobin values of 7-10 g/dl and ferritin values of < 15 microgram/l at 24 h postdelivery were randomized in two groups: one group received intravenous iron (two doses of 200 mg ferrous sucrose) on days 2 and 4 after labor and the other group received standard treatment with oral ferrous sulphate 200 mg twice daily for 6 weeks. Results: By day 7, ferritin levels were significantly higher (p = 0.002) in the group treated with intravenous iron (298.3 ± 159,1 g/l) than in that treated with oral iron (21.3 ± 9.4 g/l). Byday 14, differences between these two groups were also detected (123.7 ± 65.1 g/l in the intravenous iron group and 24.6 ± 9.3 g/l in the oral iron group, p = 0.004). Hemoglobin and hematocrit levels increased in both groups on days 7, 14 and 42 with no statistically significant differences. Adverse effects were detected in the oral iron group only (29%, n = 2), although allwere mild. Conclusions: Intravenous iron could be an alternative in the treatment of postpartum iron deficiency anemia, especially in patients who are unable to tolerate or who reject oral formulations (AU)