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1.

Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line.

Nguyen, Thao; Aida, Tomomi; Iijima-Yamashita, Yuka; Tamai, Minori; Nagamachi, Akiko; Kagami, Keiko; Komatsu, Chiaki; Kasai, Shin; Akahane, Koshi; Goi, Kumiko; Inaba, Toshiya; Sanada, Masashi; Inukai, Takeshi.

Cancer Sci ; 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38549229

2.

Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia.

Tanaka, Atsushi; Nakano, Taizo A; Nomura, Masaki; Yamazaki, Hiromi; Bewersdorf, Jan P; Mulet-Lazaro, Roger; Hogg, Simon; Liu, Bo; Penson, Alex; Yokoyama, Akihiko; Zang, Weijia; Havermans, Marije; Koizumi, Miho; Hayashi, Yasutaka; Cho, Hana; Kanai, Akinori; Lee, Stanley C; Xiao, Muran; Koike, Yui; Zhang, Yifan; Fukumoto, Miki; Aoyama, Yumi; Konuma, Tsuyoshi; Kunimoto, Hiroyoshi; Inaba, Toshiya; Nakajima, Hideaki; Honda, Hiroaki; Kawamoto, Hiroshi; Delwel, Ruud; Abdel-Wahab, Omar; Inoue, Daichi.

Blood ; 140(8): 875-888, 2022 08 25.

Artículo en Inglés | MEDLINE | ID: mdl-35709354

3.

Tumour-derived exosomes promote the induction of monocytic myeloid-derived suppressor cells from peripheral blood mononuclear cells by delivering miR-106a-5p and miR-146a-5p in multiple myeloma.

Mizuhara, Kentaro; Shimura, Yuji; Tsukamoto, Taku; Kanai, Akinori; Kuwahara-Ota, Saeko; Yamaguchi, Junko; Muramatsu, Ayako; Okamoto, Haruya; Taminishi-Katsuragawa, Yoko; Kawaji-Kanayama, Yuka; Isa, Reiko; Mizutani, Shinsuke; Inaba, Toshiya; Kuroda, Junya.

Br J Haematol ; 203(3): 426-438, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37584109

4.

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.

Sera, Yasuyuki; Nakata, Yuichiro; Ueda, Takeshi; Yamasaki, Norimasa; Koide, Shuhei; Kobayashi, Hiroshi; Ikeda, Ken-Ichiro; Kobatake, Kohei; Iwasaki, Masayuki; Oda, Hideaki; Wolff, Linda; Kanai, Akinori; Nagamachi, Akiko; Inaba, Toshiya; Sotomaru, Yusuke; Ichinohe, Tatsuo; Koizumi, Miho; Miyakawa, Yoshihiko; Honda, Zen-Ichiro; Iwama, Atsushi; Suda, Toshio; Takubo, Keiyo; Honda, Hiroaki.

Blood ; 137(7): 908-922, 2021 02 18.

Artículo en Inglés | MEDLINE | ID: mdl-33174606

5.

A novel anticancer quinolone, (R)-WAC-224, has anti-leukemia activities against acute myeloid leukemia.

Mino, Tatsuji; Ureshino, Hiroshi; Ueshima, Taichi; Kashimoto, Naoki; Yamaguchi, Tomonori; Naka, Kazuhito; Inaba, Toshiya; Ichinohe, Tatsuo.

Invest New Drugs ; 41(5): 751-760, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37702844

6.

HHEX promotes myeloid transformation in cooperation with mutant ASXL1.

Takeda, Reina; Asada, Shuhei; Park, Sung-Joon; Yokoyama, Akihiko; Becker, Hans Jiro; Kanai, Akinori; Visconte, Valeria; Hershberger, Courtney; Hayashi, Yasutaka; Yonezawa, Taishi; Tamura, Moe; Fukushima, Tsuyoshi; Tanaka, Yosuke; Fukuyama, Tomofusa; Matsumoto, Akiko; Yamasaki, Satoshi; Nakai, Kenta; Yamazaki, Satoshi; Inaba, Toshiya; Shibata, Tatsuhiro; Inoue, Daichi; Honda, Hiroaki; Goyama, Susumu; Maciejewski, Jaroslaw P; Kitamura, Toshio.

Blood ; 136(14): 1670-1684, 2020 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-32492700

7.

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL.

Watanabe, Atsushi; Miyake, Kunio; Nordlund, Jessica; Syvänen, Ann-Christine; van der Weyden, Louise; Honda, Hiroaki; Yamasaki, Norimasa; Nagamachi, Akiko; Inaba, Toshiya; Ikawa, Tomokatsu; Urayama, Kevin Y; Kiyokawa, Nobutaka; Ohara, Akira; Kimura, Shunsuke; Kubota, Yasuo; Takita, Junko; Goto, Hiroaki; Sakaguchi, Kimiyoshi; Minegishi, Masayoshi; Iwamoto, Shotaro; Shinohara, Tamao; Kagami, Keiko; Abe, Masako; Akahane, Koshi; Goi, Kumiko; Sugita, Kanji; Inukai, Takeshi.

Blood ; 136(20): 2319-2333, 2020 11 12.

Artículo en Inglés | MEDLINE | ID: mdl-32573712

8.

Design, synthesis and biological evaluation of 2-pyrrolone derivatives as radioprotectors.

Satoh, Hidetoshi; Ochi, Shintaro; Mizuno, Kosuke; Saga, Yutaka; Ujita, Shohei; Toyoda, Miyu; Nishiyama, Yuichi; Tada, Kasumi; Matsushita, Yosuke; Deguchi, Yuichi; Suzuki, Keiji; Tanaka, Yoshimasa; Ueda, Hiroshi; Inaba, Toshiya; Hosoi, Yoshio; Morita, Akinori; Aoki, Shin.

Bioorg Med Chem ; 67: 116764, 2022 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-35635928

9.

[Mouse models of hematological diseases using genome editing technology].

Nagamachi, Akiko; Inaba, Toshiya.

Rinsho Ketsueki ; 63(11): 1551-1557, 2022.

Artículo en Japonés | MEDLINE | ID: mdl-36476797

10.

Revertant somatic mosaicism as a cause of cancer.

Inaba, Toshiya; Nagamachi, Akiko.

Cancer Sci ; 112(4): 1383-1389, 2021 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-33583097

11.

The enigma of monosomy 7.

Inaba, Toshiya; Honda, Hiroaki; Matsui, Hirotaka.

Blood ; 131(26): 2891-2898, 2018 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-29615405

12.

Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation.

Ozaki, Yuko; Matsui, Hirotaka; Asou, Hiroya; Nagamachi, Akiko; Aki, Daisuke; Honda, Hiroaki; Yasunaga, Shin'ichiro; Takihara, Yoshihiro; Yamamoto, Tadashi; Izumi, Shunsuke; Ohsugi, Miho; Inaba, Toshiya.

Mol Cell ; 47(5): 694-706, 2012 Sep 14.

Artículo en Inglés | MEDLINE | ID: mdl-22864114

13.

Acquired expression of Cbl^Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.

Nakata, Yuichiro; Ueda, Takeshi; Nagamachi, Akiko; Yamasaki, Norimasa; Ikeda, Ken-Ichiro; Sera, Yasuyuki; Takubo, Keiyo; Kanai, Akinori; Oda, Hideaki; Sanada, Masashi; Ogawa, Seishi; Tsuji, Kohichiro; Ebihara, Yasuhiro; Wolff, Linda; Honda, Zen-Ichiro; Suda, Toshio; Inaba, Toshiya; Honda, Hiroaki.

Blood ; 129(15): 2148-2160, 2017 04 13.

Artículo en Inglés | MEDLINE | ID: mdl-28209720

14.

Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.

Ueda, Takeshi; Nakata, Yuichiro; Nagamachi, Akiko; Yamasaki, Norimasa; Kanai, Akinori; Sera, Yasuyuki; Sasaki, Masato; Matsui, Hirotaka; Honda, Zen-Ichiro; Oda, Hideaki; Wolff, Linda; Inaba, Toshiya; Honda, Hiroaki.

Proc Natl Acad Sci U S A ; 113(37): 10370-5, 2016 09 13.

Artículo en Inglés | MEDLINE | ID: mdl-27578866

15.

[Monosomy 7: recent progress].

Inaba, Toshiya; Nagamachi, Akiko.

Rinsho Ketsueki ; 60(9): 1020-1026, 2019.

Artículo en Japonés | MEDLINE | ID: mdl-31597823

16.

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2.

Ueda, Takeshi; Nagamachi, Akiko; Takubo, Keiyo; Yamasaki, Norimasa; Matsui, Hirotaka; Kanai, Akinori; Nakata, Yuichiro; Ikeda, Kenichiro; Konuma, Takaaki; Oda, Hideaki; Wolff, Linda; Honda, Zen-ichiro; Wu, Xudong; Helin, Kristian; Iwama, Atsushi; Suda, Toshio; Inaba, Toshiya; Honda, Hiroaki.

Blood ; 125(22): 3437-46, 2015 May 28.

Artículo en Inglés | MEDLINE | ID: mdl-25872778

17.

Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.

Sera, Yasuyuki; Yamasaki, Norimasa; Oda, Hideaki; Nagamachi, Akiko; Wolff, Linda; Inukai, Takeshi; Inaba, Toshiya; Honda, Hiroaki.

Cancer Sci ; 107(7): 890-8, 2016 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-27088431

18.

MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters.

Okuda, Hiroshi; Kawaguchi, Marie; Kanai, Akinori; Matsui, Hirotaka; Kawamura, Takeshi; Inaba, Toshiya; Kitabayashi, Issay; Yokoyama, Akihiko.

Nucleic Acids Res ; 42(7): 4241-56, 2014 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-24465000

19.

Novel functional small RNAs are selectively loaded onto mammalian Ago1.

Yamakawa, Natsuko; Okuyama, Kazuki; Ogata, Jun; Kanai, Akinori; Helwak, Aleksandra; Takamatsu, Masako; Imadome, Ken-ichi; Takakura, Kohei; Chanda, Bidisha; Kurosaki, Natsumi; Yamamoto, Haruna; Ando, Kiyoshi; Matsui, Hirotaka; Inaba, Toshiya; Kotani, Ai.

Nucleic Acids Res ; 42(8): 5289-301, 2014 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-24627180

20.

Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells.

Nagamachi, Akiko; Kikuchi, Jiro; Kanai, Akinori; Furukawa, Yusuke; Inaba, Toshiya.

Haematologica ; 105(7): e325-e327, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-31672901

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