RESUMEN
Two new sesquiterpenes, litseachrandaevanes C and D (1 and 2), together with five known sesquiterpenes (3 - 7), were isolated from the stems of Fissistigma glaucescens (Hance) Merr. Their structures were elucidated using comprehensive spectroscopic methods. The inhibitory effect of all compounds on the proliferation of primary synovial cells was evaluated. Compound 3 showed inhibitory effect on the proliferation of synoviocytes, with an IC50 value of 12.5 µM.
Asunto(s)
Annonaceae , Sesquiterpenos , Sinoviocitos , Annonaceae/química , Proliferación Celular , Estructura Molecular , Sesquiterpenos/química , Sesquiterpenos/farmacologíaRESUMEN
Two new anthraquinone derivatives sapranquinones A and B (1 and 2) together with two known biogenetically related anthraquinone derivatives (3 and 4) were isolated from the stems of Saprosma crassipes H. S. Lo. The structures of these compounds were elucidated using comprehensive spectroscopic methods. Compounds 1-4 were evaluated for their antibacterial activities and compounds 1 and 3 had a broad spectrum antibacterial activity against Staphylococcus albus, Escherichia coli, Bacillus cereus, Micrococcus tetragenus, and Micrococcus luteus with MIC values ranging from 1.25 to 5 µg/mL.
Asunto(s)
Antraquinonas , Rubiaceae , Antraquinonas/química , Antibacterianos/química , Extractos Vegetales/farmacología , Extractos Vegetales/química , Análisis Espectral , Rubiaceae/química , Escherichia coli , Pruebas de Sensibilidad MicrobianaRESUMEN
�In recent years, with the development of novel ultrasonic techniques, ultrasonography has been widely used as a non-invasive examination method in the diagnosis and treatment of pulmonary tuberculosis. Conventional ultrasound combined with contrast-enhanced ultrasound has great significance in the diagnosis and the long-term observation of treatment of tuberculosis, contrast-enhanced ultrasound combined with interventional ultrasound techniques can improve the success rate of percutaneous lung puncture, and endobronchial ultrasound has definite diagnostic value for pulmonary tuberculosis patients with negative results in sputum smear or sputum culture bacteriological examination. In this paper, we reviewed the progress of conventional ultrasound, contrast-enhanced ultrasound, ultrasound-guided percutaneous lung puncture and endobronchial ultrasound in the diagnosis of pulmonary tuberculosis.