Detalles de la búsqueda
1.
Synthesis of 2-Aryl Indazole: Synthesis, Biological Evaluationand In-Silico Studies.
Chem Biodivers
; : e202302085, 2024 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38666662
2.
C-Dimethylated Flavones as Possible Potential Anti-Tubercular and Anticancer Agents.
Chem Biodivers
; 20(4): e202201201, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36938695
3.
Synthesis and characterization of two known and one new impurities of dolutegravir: In silico evaluation of certain intermediates against SARS CoV-2 O-ribose methyltransferase (OMTase).
J Mol Struct
; 1271: 133992, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36034527
4.
Ultrasound assisted Cu-catalyzed Ullmann-Goldberg type coupling-cyclization in a single pot: Synthesis and in silico evaluation of 11H-pyrido[2,1-b]quinazolin-11-ones against SARS-CoV-2 RdRp.
J Mol Struct
; 1280: 135044, 2023 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36743447
5.
CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling-cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors.
Bioorg Chem
; 115: 105265, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34426160
6.
Pyrrolo[2,3-b]quinoxalines in attenuating cytokine storm in COVID-19: their sonochemical synthesis and in silico / in vitro assessment.
J Mol Struct
; 1230: 129868, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33424034
7.
1,2,3-Triazole-nimesulide hybrid: Their design, synthesis and evaluation as potential anticancer agents.
Bioorg Med Chem Lett
; 27(3): 518-523, 2017 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28011214
8.
Design of new hybrid template by linking quinoline, triazole and dihydroquinoline pharmacophoric groups: A greener approach to novel polyazaheterocycles as cytotoxic agents.
Bioorg Med Chem Lett
; 25(5): 1057-63, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25655719
9.
Synthesis and in vitro anti-proliferative effects of 3-(hetero)aryl substituted 3-[(prop-2-ynyloxy)(thiophen-2-yl)methyl]pyridine derivatives on various cancer cell lines.
Bioorg Med Chem Lett
; 24(5): 1366-72, 2014 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24513041
10.
Synthesis of 2H-1,3-benzoxazin-4(3H)-one derivatives containing indole moiety: their in vitro evaluation against PDE4B.
Bioorg Med Chem Lett
; 24(4): 1166-71, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24440301
11.
A direct access to bioactive fused N-heterocyclic acetic acid derivatives.
Org Biomol Chem
; 12(16): 2514-8, 2014 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24618745
12.
Synthesis of 1,2,3-triazole-piperazin-benzo[b][1,4]thiazine 1,1-dioxides: antibacterial, hemolytic and in silico TLR4 protein inhibitory activities.
RSC Adv
; 14(13): 8921-8931, 2024 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38500620
13.
Pyrazole-based and N,N-diethylcarbamate functionalized some novel aurone analogs: Design, synthesis, cytotoxic evaluation, docking and SAR studies, against AGS cancer cell line.
Heliyon
; 10(5): e26843, 2024 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38463825
14.
Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cells.
Bioorg Med Chem Lett
; 23(24): 6721-7, 2013 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24215890
15.
Novel alkynyl substituted 3,4-dihydropyrimidin-2(1H)-one derivatives as potential inhibitors of chorismate mutase.
Bioorg Chem
; 51: 48-53, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24012092
16.
Identification of novel C-15 fluoro isosteviol derivatives for GABA-AT inhibition by in silico investigations.
J Mol Model
; 29(3): 76, 2023 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36826597
17.
Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agents.
Bioorg Med Chem Lett
; 22(14): 4629-35, 2012 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22726932
18.
C-C bond formation at C-2 of a quinoline ring: synthesis of 2-(1H-indol-3-yl)quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitors.
Bioorg Med Chem
; 20(7): 2199-207, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22386978
19.
AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: a one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents.
Bioorg Med Chem
; 20(5): 1711-22, 2012 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22316553
20.
Novel 1-alkynyl substituted 1,2-dihydroquinoline derivatives from nimesulide (and their 2-oxo analogues): a new strategy to identify inhibitors of PDE4B.
Bioorg Med Chem Lett
; 21(21): 6573-6, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21920740