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1.

Triumphs and Challenges of Natural Product Discovery in the Postgenomic Era.

Cano-Prieto, Carolina; Undabarrena, Agustina; de Carvalho, Ana Calheiros; Keasling, Jay D; Cruz-Morales, Pablo.

Annu Rev Biochem ; 2024 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-38639989

2.

Biofuels for a sustainable future.

Liu, Yuzhong; Cruz-Morales, Pablo; Zargar, Amin; Belcher, Michael S; Pang, Bo; Englund, Elias; Dan, Qingyun; Yin, Kevin; Keasling, Jay D.

Cell ; 184(6): 1636-1647, 2021 03 18.

Artículo en Inglés | MEDLINE | ID: mdl-33639085

3.

Engineering Cellular Metabolism.

Nielsen, Jens; Keasling, Jay D.

Cell ; 164(6): 1185-1197, 2016 Mar 10.

Artículo en Inglés | MEDLINE | ID: mdl-26967285

4.

Complete biosynthesis of QS-21 in engineered yeast.

Liu, Yuzhong; Zhao, Xixi; Gan, Fei; Chen, Xiaoyue; Deng, Kai; Crowe, Samantha A; Hudson, Graham A; Belcher, Michael S; Schmidt, Matthias; Astolfi, Maria C T; Kosina, Suzanne M; Pang, Bo; Shao, Minglong; Yin, Jing; Sirirungruang, Sasilada; Iavarone, Anthony T; Reed, James; Martin, Laetitia B B; El-Demerdash, Amr; Kikuchi, Shingo; Misra, Rajesh Chandra; Liang, Xiaomeng; Cronce, Michael J; Chen, Xiulai; Zhan, Chunjun; Kakumanu, Ramu; Baidoo, Edward E K; Chen, Yan; Petzold, Christopher J; Northen, Trent R; Osbourn, Anne; Scheller, Henrik; Keasling, Jay D.

Nature ; 2024 May 08.

Artículo en Inglés | MEDLINE | ID: mdl-38720067

5.

Integrating biological redesign: where synthetic biology came from and where it needs to go.

Way, Jeffrey C; Collins, James J; Keasling, Jay D; Silver, Pamela A.

Cell ; 157(1): 151-61, 2014 Mar 27.

Artículo en Inglés | MEDLINE | ID: mdl-24679533

6.

Complete integration of carbene-transfer chemistry into biosynthesis.

Huang, Jing; Quest, Andrew; Cruz-Morales, Pablo; Deng, Kai; Pereira, Jose Henrique; Van Cura, Devon; Kakumanu, Ramu; Baidoo, Edward E K; Dan, Qingyun; Chen, Yan; Petzold, Christopher J; Northen, Trent R; Adams, Paul D; Clark, Douglas S; Balskus, Emily P; Hartwig, John F; Mukhopadhyay, Aindrila; Keasling, Jay D.

Nature ; 617(7960): 403-408, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37138074

7.

A microbial supply chain for production of the anti-cancer drug vinblastine.

Zhang, Jie; Hansen, Lea G; Gudich, Olga; Viehrig, Konrad; Lassen, Lærke M M; Schrübbers, Lars; Adhikari, Khem B; Rubaszka, Paulina; Carrasquer-Alvarez, Elena; Chen, Ling; D'Ambrosio, Vasil; Lehka, Beata; Haidar, Ahmad K; Nallapareddy, Saranya; Giannakou, Konstantina; Laloux, Marcos; Arsovska, Dushica; Jørgensen, Marcus A K; Chan, Leanne Jade G; Kristensen, Mette; Christensen, Hanne B; Sudarsan, Suresh; Stander, Emily A; Baidoo, Edward; Petzold, Christopher J; Wulff, Tune; O'Connor, Sarah E; Courdavault, Vincent; Jensen, Michael K; Keasling, Jay D.

Nature ; 609(7926): 341-347, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-36045295

8.

Retrograde signaling by the plastidial metabolite MEcPP regulates expression of nuclear stress-response genes.

Xiao, Yanmei; Savchenko, Tatyana; Baidoo, Edward E K; Chehab, Wassim E; Hayden, Daniel M; Tolstikov, Vladimir; Corwin, Jason A; Kliebenstein, Daniel J; Keasling, Jay D; Dehesh, Katayoon.

Cell ; 149(7): 1525-35, 2012 Jun 22.

Artículo en Inglés | MEDLINE | ID: mdl-22726439

9.

Complete biosynthesis of the potent vaccine adjuvant QS-21.

Martin, Laetitia B B; Kikuchi, Shingo; Rejzek, Martin; Owen, Charlotte; Reed, James; Orme, Anastasia; Misra, Rajesh C; El-Demerdash, Amr; Hill, Lionel; Hodgson, Hannah; Liu, Yuzhong; Keasling, Jay D; Field, Robert A; Truman, Andrew W; Osbourn, Anne.

Nat Chem Biol ; 20(4): 493-502, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38278997

10.

Author Correction: Complete biosynthesis of cannabinoids and their unnatural analogues in yeast.

Luo, Xiaozhou; Reiter, Michael A; d'Espaux, Leo; Wong, Jeff; Denby, Charles M; Lechner, Anna; Zhang, Yunfeng; Grzybowski, Adrian T; Harth, Simon; Lin, Weiyin; Lee, Hyunsu; Yu, Changhua; Shin, John; Deng, Kai; Benites, Veronica T; Wang, George; Baidoo, Edward E K; Chen, Yan; Dev, Ishaan; Petzold, Christopher J; Keasling, Jay D.

Nature ; 580(7802): E2, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32269333

11.

High-throughput metabolic engineering: advances in small-molecule screening and selection.

Dietrich, Jeffrey A; McKee, Adrienne E; Keasling, Jay D.

Annu Rev Biochem ; 79: 563-90, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-20367033

12.

Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast.

Bradley, Samuel A; Lehka, Beata J; Hansson, Frederik G; Adhikari, Khem B; Rago, Daniela; Rubaszka, Paulina; Haidar, Ahmad K; Chen, Ling; Hansen, Lea G; Gudich, Olga; Giannakou, Konstantina; Lengger, Bettina; Gill, Ryan T; Nakamura, Yoko; de Bernonville, Thomas Dugé; Koudounas, Konstantinos; Romero-Suarez, David; Ding, Ling; Qiao, Yijun; Frimurer, Thomas M; Petersen, Anja A; Besseau, Sébastien; Kumar, Sandeep; Gautron, Nicolas; Melin, Celine; Marc, Jillian; Jeanneau, Remi; O'Connor, Sarah E; Courdavault, Vincent; Keasling, Jay D; Zhang, Jie; Jensen, Michael K.

Nat Chem Biol ; 19(12): 1551-1560, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-37932529

13.

Foldy: An open-source web application for interactive protein structure analysis.

Roberts, Jacob B; Nava, Alberto A; Pearson, Allison N; Incha, Matthew R; Valencia, Luis E; Ma, Melody; Rao, Abhay; Keasling, Jay D.

PLoS Comput Biol ; 20(2): e1011171, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38306398

14.

teemi: An open-source literate programming approach for iterative design-build-test-learn cycles in bioengineering.

Petersen, Søren D; Levassor, Lucas; Pedersen, Christine M; Madsen, Jan; Hansen, Lea G; Zhang, Jie; Haidar, Ahmad K; Frandsen, Rasmus J N; Keasling, Jay D; Weber, Tilmann; Sonnenschein, Nikolaus; K Jensen, Michael.

PLoS Comput Biol ; 20(3): e1011929, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38457467

15.

Engineering static and dynamic control of synthetic pathways.

Holtz, William J; Keasling, Jay D.

Cell ; 140(1): 19-23, 2010 Jan 08.

Artículo en Inglés | MEDLINE | ID: mdl-20085699

16.

Complete biosynthesis of cannabinoids and their unnatural analogues in yeast.

Luo, Xiaozhou; Reiter, Michael A; d'Espaux, Leo; Wong, Jeff; Denby, Charles M; Lechner, Anna; Zhang, Yunfeng; Grzybowski, Adrian T; Harth, Simon; Lin, Weiyin; Lee, Hyunsu; Yu, Changhua; Shin, John; Deng, Kai; Benites, Veronica T; Wang, George; Baidoo, Edward E K; Chen, Yan; Dev, Ishaan; Petzold, Christopher J; Keasling, Jay D.

Nature ; 567(7746): 123-126, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30814733

17.

ClusterCAD 2.0: an updated computational platform for chimeric type I polyketide synthase and nonribosomal peptide synthetase design.

Tao, Xavier B; LaFrance, Sarah; Xing, Yifei; Nava, Alberto A; Martin, Hector Garcia; Keasling, Jay D; Backman, Tyler W H.

Nucleic Acids Res ; 51(D1): D532-D538, 2023 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-36416273

18.

One-pot selective biosynthesis of Tyrian purple in Escherichia coli.

Li, Feifei; Chen, Que; Deng, Huaxiang; Ye, Shumei; Chen, Ruidong; Keasling, Jay D; Luo, Xiaozhou.

Metab Eng ; 81: 100-109, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-38000548

19.

Development of Corynebacterium glutamicum as a monoterpene production platform.

Luckie, Bridget A; Kashyap, Meera; Pearson, Allison N; Chen, Yan; Liu, Yuzhong; Valencia, Luis E; Carrillo Romero, Alexander; Hudson, Graham A; Tao, Xavier B; Wu, Bryan; Petzold, Christopher J; Keasling, Jay D.

Metab Eng ; 81: 110-122, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-38056688

20.

BayFlux: A Bayesian method to quantify metabolic Fluxes and their uncertainty at the genome scale.

Backman, Tyler W H; Schenk, Christina; Radivojevic, Tijana; Ando, David; Singh, Jahnavi; Czajka, Jeffrey J; Costello, Zak; Keasling, Jay D; Tang, Yinjie; Akhmatskaya, Elena; Garcia Martin, Hector.

PLoS Comput Biol ; 19(11): e1011111, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37948450

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