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J Biomed Nanotechnol ; 9(10): 1716-23, 2013 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-24015501

RESUMEN

Xylose is a natural monosaccharide found in biomass such as straw, pecan shells, cottonseed hulls, and corncobs. Using this monosaccharide, we report the facile, green synthesis and characterization of stable xylose encapsulated gold nanoparticles (Xyl-GNPs) with potent antibacterial activity. Xyl-GNPs were synthesized using the reduction property of xylose in an aqueous solution containing choloraurate anions carried out at room temperature and atmospheric pressure. These nanoparticles were stable and near spherical in shape with an average diameter of 15 +/- 5 nm. Microbiological assay results showed the concentration dependent antibacterial activity of these particles against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus epidermidis) bacteria. Thus the facile, environmentally friendly Xyl-GNPs have many potential applications in chemical and biomedical industries, particularly in the development of antibacterial agents in the field of biomedicine.


Asunto(s)
Escherichia coli/efectos de los fármacos , Oro/química , Oro/farmacología , Nanopartículas del Metal/administración & dosificación , Nanopartículas del Metal/química , Staphylococcus epidermidis/efectos de los fármacos , Antibacterianos/administración & dosificación , Antibacterianos/síntesis química , Supervivencia Celular/efectos de los fármacos , Escherichia coli/citología , Ensayo de Materiales , Nanopartículas del Metal/ultraestructura , Tamaño de la Partícula , Staphylococcus epidermidis/citología
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