Rising Incidence of Childhood Intussusception in Ontario: A Population-Based Study From 1997-2016.

BACKGROUND: Intussusception is the most common cause of bowel obstruction in children aged 3 months to 6 years of age. We sought to describe patterns of incident childhood intussusception. METHODS: A retrospective longitudinal cohort study utilizing population-based health administrative data and a validated case definition was used to identify patients <18 years of age treated for intussusception between January 1, 1997 and December 31, 2016 in Ontario, Canada. Descriptive statistics, graphical analyses, and a Poisson regression model were performed for trend analysis. RESULTS: The overall incidence of intussusception in Ontario children (<18 years) was 3.3 cases/100,000 child years (cyrs), 95% CI [3.2.3.5]. The overall incidence increased from .9 cases/100,000 cyrs to 2.3 cases/100,000 cyrs. The highest incidence was in children aged 6-12 months at 28.9 cases/100,000 cyrs, 95% CI [26.2.31.9]. Incidence increased in all age-groups between 6 months and 5 years (at a rate of 5% to 16% per year; all P < .05). Month of year did not predict intussusception counts in a log-linear Poisson models, nor did rotavirus immunization implementation in 2011. There was a 3-fold variability across geographic areas in the province. There was a high rate of readmission for recurrence within 1 year (10.7%). CONCLUSION: The incidence of intussusception more than doubled in Ontario from 1997 to 2016. The incidence increased for children aged between 6 months and 5 years at a rate of 5-16% per year, suggesting that an increased rate of idiopathic intussusception is responsible for the increase in the province.

Caudal catheter placement for repeated epidural morphine doses after neonatal upper abdominal surgery.

Effective pain control after major surgery in neonates presents many challenges. Parenteral opioids (and co-analgesics) are often used but inadequate analgesia and oversedation are not uncommon. Although continuous thoracic epidural analgesia is highly effective and opioid-sparing, its associated risks and the need for staff with specialised skills and/or neonatal intensive care unit staff buy-in may preclude this option even in many academic centres. We present the case of a six-day-old infant who underwent upper abdominal surgery and received intermittent morphine doses via a tunnelled caudal epidural catheter, which provided satisfactory analgesia and facilitated early extubation.

Imaging features and enhancement technique to diagnose and classify intrathoracic Lymphatic-venous malformations: A case report and literature review.

The diagnosis and treatment of pediatric intrathoracic lymphatic-venous malformations (LVM) can be complex due to their rarity, variable presentation and confusing nomenclature in the literature. The International Society for the Study of Vascular Anomalies (ISSVA) has recently (2018) updated their classification to help guide the correct diagnosis, nomenclature and management of such cases. We present the case of a 12-month-old Caucasian female with a lymph-venous malformation (LVM) classified in the updated ISSVA classification as a combined vascular malformation (CLVM) defined as two or more vascular malformations found in one lesion, associated with an underlying "malformation of an individual named vessel". The patient presented with tachypnea, tachycardia and fever. While all the previous cases underwent surgical treatment, our patient was successfully treated with rapamycin and sclerotherapy. Appropriate imaging can aid in the diagnosis of vascular anomalies and in the proper ISSVA classification, saving the patient the need for a biopsy and allow for proper referral to Multidisciplinary Vascular Anomalies centers. The accurate classification can identify cases that can be treated through Interventional Radiology with sclerosing agents and medical therapy as opposed to surgery.

Diagnosis and treatment of childhood intussusception from 1997 to 2016: A population-based study.

OBJECTIVES: Describe changes in the diagnostic approach and treatment for pediatric intussusception over two decades. STUDY DESIGN: Administrative universal healthcare data were used to conduct a population-based cohort study of intussusception between January 1997 and December 2016 in Ontario, Canada. A validated case definition was used to identify all patients (<18 years) treated for intussusception in the province at community or tertiary care centers. Treatment modality was determined using physician billing data and databases linked at ICES; it was categorized as nonoperative alone, surgical alone, or failed nonoperative. Descriptive statistics, Cochrane-Armitage for trend analyses, and graphical and multinomial logistic regression were performed. RESULTS: Over 20 years, 1895 pediatric patients were treated for intussusception. Pretreatment imaging use rose from 57.5% to 99.3%. Nonoperative management increased from 23.4% to 75.2%. However, 43% of children who presented to a community hospital underwent immediate surgical management, compared with just 11% of children at tertiary centers (RR 0.39, 95% CI: 0.25-0.62). Among children who underwent surgery, there was an increase in bowel resection over time (41.7% to 57.6%). CONCLUSIONS: Over the 20 year period of study, pretreatment imaging became universal, and management shifted from predominantly surgical to nonoperative reduction in Ontario. The rate of surgical intervention remains higher in community versus tertiary centers. LEVEL OF EVIDENCE: Treatment study, III.

The cost of childhood intussusception in Ontario from 2003 to 2016: A population-based study.

BACKGROUND: Management of pediatric intussusception has evolved to favor non-surgical reduction with potential outpatient management. The overall impact of these changes on healthcare costs is unknown. METHODS: A retrospective longitudinal cohort study was conducted utilizing population-based universal-access administrative healthcare data to identify patients <18 years treated for intussusception January 2003-December 2016 in Ontario, Canada. Hospital-associated cost included emergency department and cost of hospitalization, while total cost also included billable physician costs. All costs are presented in 2016 Canadian Dollars. RESULTS: The median hospital-associated costs for each modality were: non-surgical $2467, failed non-surgical $6508, and surgical only $8863 (p < 0.0001). Costs associated with non-surgical or surgical only management did not change over the study period, whereas costs associated with failed non-surgical management increased from $3842 in 2003 to $12,350 in 2016 (p = 0.0003). Similar trends were observed when physician billing data was included. Costs were $1076.95 higher in community hospitals than academic hospitals (95% CI: $344, $1810; p = 0.004). CONCLUSION: The cost of care for intussusception is dependent upon treatment modality and was lowest for non-surgical management and highest for patients treated in community hospitals. Efforts to standardize care to promote successful non-surgical management and to facilitate early discharge could provide cost savings to the healthcare system. TYPE OF STUDY: Cost Effectiveness Study. LEVEL OF EVIDENCE: IV.

A technical skills elective program for pre-clerkship medical students reduces levels of high anxiety for performing technical skills.

BACKGROUND: We investigated the effect of a simulation-based technical skills course on rates of high anxiety reported by pre-clerkship medical students for basic and advanced technical skills. METHODS: Twenty-two second year medical students reported levels of anxiety by electronic survey for 21 technical skills before and after the course. A peer group of 75 students were invited to complete the survey for comparison. RESULTS: We received 21 (95.5%) responses before and after the course, and 12 (57.1%) in a three-month follow-up. Rates of high anxiety ranged from 19 to 86% across skills before the course and 0-48% afterward. There was no statistically significant difference in high anxiety reported in a three-month follow-up survey. The rates of high anxiety reported were reduced across all skills for course participants compared to the responding peer group of 32 (42.7%), reaching a statistically significant difference for 15/21 skills (P < 0.05). CONCLUSIONS: Participation in this technical skills course was associated with decreased reports of high anxiety by pre-clerkship medical students regarding the performance of basic and advanced technical skills.

Factors affecting perception of the normal pediatric appendix on sonography.

BACKGROUND: To determine if an inherent perception skill along with sonographer experience, knowledge base, scanning time play a role in the identification of the normal appendix in the pediatric population. This is a retrospective review of pediatric (< 18 years old) patients with a clinical suspicion of acute appendicitis presenting to the emergency department of two affiliated academic tertiary care hospitals over a 1-year time span. All patients had a sonogram performed by 1/15 sonographers or by 1/8 on-call radiology residents. Those with a normal or non-visualized appendix with subsequent discharge from ER were included in the study. Patient demographics, minutes spent scanning, and sonographer years of experience in general abdominal scanning and residents level of training were recorded. RESULTS: Of the 127 patients included in the study, 51 (40%) were male and 76 (60%) were female, with a mean age of 11.8 ± 4.2 years. Sonographers who failed to see a normal appendix had less experience (median 8 years) than those who did visualize the appendix (median 15 years), p ≤ 0.001. Longer time spent scanning was also associated with visualizing a normal appendix (20.4 versus 29.1 min, p = 0.001). In multivariable logistic regression, more time spent scanning (OR 1.04, 95% CI 1.01, 1.07, p = 0.012) and increased sonographer experience (OR 1.07, 95% CI 1.02, 1.13, p = 0.012) resulted in greater odds of perceiving the appendix. The top 4 were significantly more likely to visualize the appendix (88.0%) than all of the other combined (20.8%, p < 0.001), and they also had substantially more experience (median 15 years versus 8 years, p < 0.001). Overall, sonographers were more likely to see a normal appendix (61%) than the residents (14%), p < 0.001. CONCLUSION: Sonography to rule out appendicitis in the pediatric patient is in general most successful when performed by experienced sonographers with adequate time to perform the scan. Triaging patients to those sonographers who have displayed optimal perceptual ability of the normal appendix may help optimize patient care and hospital resources. Having experienced sonographers available after hours would allow for optimal care in the setting of 'query' appendicitis.

Laparoscopic duodenoduodenostomy in a newborn with situs inversus totalis.

Situs viscerum inversus is a rare embryologic anomaly with a mirror-image transposition of the normal anatomy of organs. The coexistence with the duodenal atresia is extremely rare. This report describes a newborn with duodenal atresia and situs inversus totalis who was managed laparoscopically. According to our knowledge, this is the first report of this type of associated anomaly to be successfully managed by the laparoscopic approach.

Scapular Bronchogenic Cyst in a Girl Presenting as Recurrent Cellulitis: A Case Report and Review of the Literature.

Bronchogenic cysts are rare, congenital cysts originating from respiratory epithelium and typically found within the chest. Cutaneous bronchogenic cysts are exceedingly uncommon, with only 19 reported cases in the scapular region and almost exclusively occurring in male patients. Herein, we present the case of a female patient with recurrent cellulitis secondary to a bronchogenic cyst, which was diagnosed after surgical excision. We also provide a review of the literature to consolidate the current understanding of cutaneous scapular bronchogenic cysts. To our knowledge, this is the first such case reported from Canada.

The Development and Implementation of New Assessment Tools for the Surgical Clerkship Rotation.

This article was migrated. The article was marked as recommended. Innovation: We developed two new rubrics with explicit behavioural anchors to assess students in the Queen's undergraduate medical education (UGME) surgery clerkship rotation. These rotation rubrics, complemented by a new ambulatory clinic encounter card, improved the quality, consistency, and timeliness of feedback for clerks from faculty preceptors. This innovation was introduced during a comprehensive workplace-based assessment re-design being undertaken in the Department of Surgery as part of the transition to a post-graduate competency-based medical education (CBME) system for post-graduate education (PGME). The core UGME working group, comprised of a faculty surgeon, assessment consultant, and a surgical resident, selected terminology and designed the tool visual structure to be similar to the new post-graduate assessment tools, since most preceptors supervise learners in both programs. This consistency enhanced buy-in from faculty and ensured a smooth transition to the use of the new UGME tools. Development: The new assessment process was developed and piloted in three phases: (1) development of an assessment system based on rubrics with explicit behavioural descriptors as the key assessment tools; (2) implementation of a pilot study to establish the acceptability and feasibility of the use of these rubrics, with iterative revisions based on stakeholder feedback; and (3) development of a validity argument for the use of these assessment tools. The latter is scheduled for 2018. Outcomes: The use of these rotation behaviour-anchored rubrics and corresponding ambulatory clinic encounter card has greatly improved the mid- and final-rotation feedback provided to students on the Surgery Clerkship. The concrete, descriptive information provided by the rubrics allows the course director to provide specific feedback during rotation exit meetings. The course director has the ability to clearly articulate to students the areas where they have met (or exceeded) the expected level of competency, as well as areas which require additional attention.

Duodenotubular Flap-New Biliary Reconstructive Procedure.

BACKGROUND: Although Roux-en-Y hepaticojejunostomy is considered the gold standard of biliary reconstruction after excision of a choledochal cyst, there is increasing popularity of hepaticoduodenostomy, as it is easier to perform laparoscopically and provides physiologic bile drainage into the duodenum. Our animal research study had the goal to develop and test a new biliary reconstructive procedure (the duodenotubular flap [DTF]), with the advantages of providing physiological bile flow into the duodenum, technical simplicity of duodenal conduit construction, and ability of endoscopic assessment in case of complications. MATERIALS AND METHODS: The DTF procedure consists of transection of the common bile duct (CBD), construction of the DTF from the second part of the duodenum, and biliary-enteric anastomosis. The first group of 6 dogs underwent reconstruction as a single surgical procedure. The second group of 4 dogs underwent the DTF procedure after the preparatory step of laparoscopic clipping of the CBD (for 7 days), to simulate the pathology of the choledochal cyst (extrahepatic biliary obstruction) and to ease the anastomosis. Laboratory analyses were performed pre- and postoperatively. RESULTS: From the first group, 3 dogs developed a postoperative leak at the biliary-enteric anatomosis. The leak was recognized on postoperative day 4 in 2 dogs. They underwent an emergency abdominal exploration with redo anastomosis and had a complete recovery. The third dog died suddenly on postoperative day 10. Autopsy revealed incomplete disruption of the biliary-enteric anastomosis. In the second group, 3 dogs had an uneventful recovery, but 1 died on postoperative day 3. Autopsy revealed intraperitoneal bleeding with intact anastomotic and staple sites. None of the dogs in either group experienced leak at the staple lines, and none of the 8 surviving dogs developed postoperative cholangitis during the follow-up period from 15 to 20 months. CONCLUSIONS: The DTF procedure is feasible, simple, and quick, simulating physiological anatomy. Regarding the safety, a wide anastomosis seems to be the core of success.

[Psychological aspects of genital surgery in childhood]. / Psiholoski aspekti decje genitalne hirurgije.

Although the children's urogenital surgery is discipline in expansion which successfully solves even the most complicated anomalies of urogeniral tract, only lately there is enough attention paid on the psychological aspects of these anomalies and surgical operation on genitals. The boys with hypospadias, phimosis and other congenital anomalies represent a risky group for the difficulties in forming the sexual identity and for the appearance of different psychopathology in their childhood and later in life. The surgical operation itself presents a traumatic situation for the child and it may discredit the later psychosexual development of these boys in a great deal. The priority is increasing the sensitivity of children's surgeons for these problems, not only for modernizing the surgical operation, considering the knowledge of normal psychological stages of development, but also for recognizing the psychological phenomena on time and for the consultative joining of the appropriate experts. It is very important to work with these children's parents in view of offering them help for better accepting their child's organic problem, to be less anxious on account of the anomaly and the operation itself and to be more able for better understanding of their child's feelings and his experience. The child's actual psychological condition and his later psychosexual development depend to a great extent on their parent's correct attitude. The caustical survey of the boys with hypospadias illustrates some of the psychological problems which appear with children who had an reparation of hypospadias.

[Specific aspects of psychoses in mentally retarded children and adolescents]. / Specificnosti psihoza mentalno retardirane dece i adolescenata.

Mental retardation is a heterogenous neurodevelopmental disorder characterized by arrested or incomplete psychological development. The first part of the study deals with psychological and biological factors: etiology and pathogenesis of mental retardation and comorbid psychiatric disorders. Their etiopathogenesis is similar as in other neurodevelopmental disorders and it was analyzed in the part dealing with biological specificities of persons with mental retardation. Numerous biopsycho-social factors cause increased vulnerability of the mentally retarded to development of mental disorders. Thus, prevalence of these disorders is higher in mentally retarded persons than in general population. This study also deals with specificities regarding diagnosis of psychotic disorders in mentally retarded persons as well as neurobiologic, epidemiologic, clinical and therapeutic characteristics of schizophrenic psychoses, autism and affective disorders in persons with mental retardation. Special emphasis was given to diagnostics of these disorders in mentally retarded children and adolescents, as well as to problems of differential diagnostics. Apart from other things, we have concluded that specific clinical pictures demand subspeciality approach in the frame of developmental psychiatry.

[Percutaneous gastrostomy as an urgent method of treatment of a neonate with esophageal and duodenal atresia]. / Perkutana gastrostomija kao urgentna mera u lecenju novorodnenceta s atrezijom jednjaka i udruzenom atrezijom duodenuma.

The objective of this article was to present possibilities of percutaneous gastrostomy for management of a newborn with esophageal and duodenal atresia. Percutaneous gastrostomy is the most commonly employed technique for providing long-term enteral nutrition. In adults, it is also method of choice for decompression of digestive tract in palliative treatment of malignant and non malignant diseases. This is a case report of two-day old newborn with esophageal atresia with distal tracheoesophageal fistula and duodenal atresia. Percutaneous decompressive gastrostomy was used as a temporary bridge to definite surgery for management of respiratory dysfunction of this newborn, caused by dilated stomach. Surgical management (esophageal and duodenal reconstructions) as well as intra- and postoperative period were without any complications. Three months after surgical management, the infant is well and without any difficulties.