RESUMEN
BACKGROUND: The aim of this study was to describe the epidemiological, clinical and etiological aspects of severe cutaneous adverse drug reactions in children in dermatologyvenereology unit at National and Teaching Hospital of Cotonou. METHODS: A retrospective and descriptive study was carried out for 10 years in dermatology-venereology unit at the National and Teaching Hospital of Cotonou to document the epidemiological, clinical and etiological aspects of severe cutaneous adverse drug reactions in children. It included all children aged from 0 to 18 years with clinical diagnosis of severe cutaneous adverse drug reactions. Drug imputability was based on the criteria of the French pharmacovigilance group. RESULTS: Severe cutaneous adverse drug reactions accounted for 47.3% of paediatric cases (35/74 cases). The mean age was 9.3 years ± 5.2. The sex-ratio was 1.1. Self-medication was noted in 76.5% of children, on the initiative of parents in 66.7% of cases. There were 51.4% cases of Steven Johnson syndrome, 22.8% cases of Lyell syndrome, 8.5% cases of generalized and bullous fixed drug eruption, 2.9% cases of acute generalized exanthematous pustulosis and erythrodermic maculo-papular rash. Drug combinations was noted in 20% of cases. Penicillins (26.5%), paracetamol and sulfonamides (16.3%) were the drugs frequently incriminated. CONCLUSION: Steven Johnson syndrome and Lyell syndrome were the main severe cutaneous adverse drug reactions in children, mostly of school age. Penicillins, paracetamol and sulfonamides were the drugs frequently used and administered most often on self-medication.
INTRODUCTION: L'objectif de cette étude était de décrire les aspects épidémiologiques, cliniques et étiologiques des toxidermies graves chez les enfants en dermatologie à Cotonou. METHODES: Une étude rétrospective et descriptive a été réalisée sur 10 ans dans le service de dermatologie du Centre National Hospitalier et Universitaire de Cotonou pour documenter les aspects épidémiologiques, cliniques et étiologiques des toxidermies graves chez les enfants. Étaient inclus tous les enfants âgés de 0-18 ans chez qui le diagnostic clinique de toxidermie grave a été retenu. L'imputabilité médicamenteuse était basée sur les critères du groupe français de pharmacovigilance. RESULTATS: Les toxidermies graves représentaient 47,3% des cas pédiatriques (35/74 cas). L'âge moyen était de 9,3 ans ± 5,2. La sex-ratio H/F était de 1,1. Une automédication a été notée chez 76,5% des enfants, sur l'initiative des parents dans 66,7% des cas. Il y avait 51,4% de cas de syndrome de Steven Johnson, 22,8% de cas de syndrome de Lyell, 8,5% de cas d'érythème pigmenté fixe bulleux étendu, 2,9% de pustulose exanthématique aigüe généralisée et d'exanthème maculo-papuleux eìrythrodermique. Une polymédication a été notée dans 20% des cas. Les pénicillines (26,5%), le paracétamol et les sulfamides (16,3%) étaient les médicaments fréquemment incriminés. CONCLUSION: Le syndrome de Steven Johnson et le syndrome de Lyell étaient les principales toxidermies graves chez les enfants, majoritairement en âge scolaire. Les pénicillines, le paracétamol et les sulfamides étaient les médicaments fréquemment incriminés et administrés le plus souvent en automédication. Mots clés: Toxidermies graves, syndrome de Steven Johnson, syndrome de Lyell, automédication, sulfamides, enfants, Benin.
Asunto(s)
Dermatología , Síndrome de Stevens-Johnson , Venereología , Acetaminofén , Antibacterianos , Antiinflamatorios no Esteroideos/efectos adversos , Benin , Niño , Hospitales de Enseñanza , Humanos , Penicilinas , Estudios Retrospectivos , Síndrome de Stevens-Johnson/epidemiología , Síndrome de Stevens-Johnson/etiología , SulfonamidasRESUMEN
BACKGROUND: Cutaneous basidiobolomycosis is the most common form of entomophthoramycosis. Herein we report seven cases of cutaneous basidiobolomycosis. PATIENTS AND METHODS: A retrospective observational study was conducted at the Buruli ulcer treatment centre in Pobè and at the national teaching hospital in Cotonou from 2010 to 2015. RESULTS: Seven cases of cutaneous basidiobolomycosis were diagnosed. The mean patient age was 9.53 years. There were 4 female and 3 male patients, all from southeast Benin. Clinically, the disease presented in all cases as a hard, well-defined, subcutaneous plaque with little inflammation, and which could easily be lifted from the deep structures but remained attached to the surface structures. The overlying skin was hyperpigmented. Plaques were localized to the buttocks or thighs. All patients had inflammatory anaemia with an accelerated erythrocyte sedimentation rate (30 to 70mm over the first hour), and a low haemoglobin count (8.7 to 11.4g/dL). Blood hypereosinophilia (650 to 3784elements/mm3) was present in six of the seven subjects. Histopathology (performed for 5 of the 7 subjects) showed granulomatous lesions with foreign-body giant cells, and inflammatory cells, with occasional eosinophils surrounding fungal hyphae (Splendore-Hoeppli phenomenon). Mycological analysis revealed Basidiobolus ranarum in three cases. The patients were treated with ketoconazole (5/7) and itraconazole (2/7), with good outcomes after 10 to 24 weeks of therapy. DISCUSSION: Cutaneous basidiobolomycosis is uncommon in southern Benin, with only seven cases being diagnosed over 6 years. The diagnosis of cutaneous basidiobolomycosis is a challenge in the field in Benin due to the non-specific clinical presentation, the lack of technical resources, and the existence of numerous differential diagnoses. CONCLUSION: Cutaneous basidiobolomycosis is an uncommon fungal infection in southern Benin chiefly affecting children.
Asunto(s)
Dermatomicosis/epidemiología , Entomophthorales/aislamiento & purificación , Cigomicosis/epidemiología , Adolescente , Adulto , Antifúngicos/uso terapéutico , Benin/epidemiología , Niño , Preescolar , Estudios Transversales , Dermatomicosis/diagnóstico , Dermatomicosis/microbiología , Diagnóstico Diferencial , Eosinofilia/etiología , Femenino , Granuloma/etiología , Humanos , Hiperpigmentación/etiología , Lactante , Itraconazol/uso terapéutico , Cetoconazol/uso terapéutico , Masculino , Estudios Retrospectivos , Adulto Joven , Cigomicosis/complicaciones , Cigomicosis/diagnóstico , Cigomicosis/microbiologíaRESUMEN
BACKGROUND: Ainhum, or spontaneous dactylitis, involves the formation of a gradual constriction in the digital-plantar fold of the fifth toe that leads, after several years, to autoamputation of the digit. This condition is classically distinguished from "true" ainhum, of unknown aetiology and affecting only subjects of African origin, from "pseudo-ainhum", resulting from different causes such as inflammatory constriction or constriction by a foreign body, and finally from ainhumoid palmoplantar keratoderma, which is of genetic origin and occurs for instance in Vohwinkel syndrome. Herein, we report three cases of ainhum in women of sub-Saharan African origin; in addition, all three subjects were also presenting various forms of hyperkeratosis of the hands and feet known to primarily affect subjects of African origin. PATIENTS AND METHODS: The three patients, aged 30, 48 and 44 years, were respectively from Mali, Guinea and Senegal. They had consulted a dermatologist for violent pain in the fifth toe, which frequently prevented sleep and was inexplicable despite several consultations, and even in one case in spite of surgical investigation. Once the diagnosis had been made, relief was promptly provided for all three patients through Z-plasty to remove the circular constriction around the toe in question. In addition to ainhum, the first patient was also presenting diffuse palmoplantar keratoderma, together with an aspect of acrokeratoelastoidosis on the edges of her hands and feet, and knuckle pads, while the second was presenting diffuse palmoplantar keratoderma and an aspect of marginal acrokeratoelastoidosis, and the third was presenting small knuckle pads. DISCUSSION: A recent study has confirmed the high incidence of several forms of palmoplantar keratoderma of African origin, as well as frequent association of these different varieties with one another. These consist of diffuse keratoderma having a relatively non-specific aspect, keratoderma punctata of the palmar creases, marginal keratoderma known also as focal acral hyperkeratosis, and acrokeratoelastoidosis, despite the absence of histological evidence, and finally, inverted keratoderma, i.e. affecting the dorsal aspects of the extremities, such as knuckle pads. In the three cases presented here, ainhum was associated with these different forms of acral keratoderma seen chiefly in subjects of African origin. CONCLUSION: So-called "true" ainhum may be included in a broader group of African acral keratoderma, further reinforcing the unity of this group. Genetic studies are required to enable validation and refinement of these clinical findings.
Asunto(s)
Ainhum/etiología , Queratodermia Palmoplantar/complicaciones , Adulto , Población Negra , Femenino , Humanos , Persona de Mediana EdadRESUMEN
BACKGROUND: Dissecting cellulitis of the scalp (DCS) is a rare and long-standing disease and its aetiopathogenesis remains unclear. Various therapeutic alternatives exist. We attempted to assess the efficacy of oral isotretinoin in a series of patients. PATIENTS AND METHODS: Seven cases of DCS followed and treated by one of the authors at the Sabouraud Centre in the Saint-Louis Hospital between 2007 and 2013 were retrospectively studied and the efficacy of oral isotretinoin was evaluated. RESULTS: The seven patients included were males aged between 22 and 39 years, with alopecic nodules on the occiput (two cases) or the top of the vertex (five cases). Most patients were given oral isotretinoin at a dosage of 0.75mg/kg/day for at least nine months. The outcome was satisfactory with complete healing of the lesions and good regrowth in all cases. Follow-up after recovery lasted between 16 and 42 months. CONCLUSION: Based on published studies and the results of the present study, oral isotretinoin at a dose of 0.75mg/kg/day may be proposed as first-line treatment for DCS.
Asunto(s)
Celulitis (Flemón)/tratamiento farmacológico , Fármacos Dermatológicos/administración & dosificación , Isotretinoína/administración & dosificación , Dermatosis del Cuero Cabelludo/tratamiento farmacológico , Administración Oral , Adulto , Humanos , Masculino , Estudios Retrospectivos , Adulto JovenRESUMEN
BACKGROUND: Urticarial vasculitis (UV) is a rare form of leukocytoclastic vasculitis in which skin lesions resemble urticaria. UV comprises hypocomplementemic and normocomplementemic subtypes. To date, only 4 cases of UV associated with myeloproliferative disorders have been described, including 3 cases with essential thrombocythaemia (ET) and one case with polycythaemia vera. PATIENTS AND METHODS: We describe the case of a 59-year-old male patient with JAK2-positive TE and secondary myelofibrosis and who developed multiple urticarial papules persisting for more than 24hours. Skin biopsy showed perivascular neutrophilic infiltrate with margination of neutrophils in the lumen of vessels and some leukocytoclastic patterns, and with red cell extravasation consistent with UV. Treatment with ruxolitinib (a JAK2 inhibitor) induced transient and partial control of the haematological symptoms but did not prevent UV flare. Prednisolone 20mg once daily was added, with good clinical response. DISCUSSION AND CONCLUSION: To our knowledge, this is the fourth reported case of UV associated with ET and the first case associated with MF.
Asunto(s)
Médula Ósea/patología , Trastornos Mieloproliferativos/complicaciones , Urticaria/etiología , Vasculitis Leucocitoclástica Cutánea/etiología , Quimioterapia Combinada , Resultado Fatal , Humanos , Janus Quinasa 2/antagonistas & inhibidores , Masculino , Persona de Mediana Edad , Mutación Missense , Trastornos Mieloproliferativos/tratamiento farmacológico , Nitrilos , Prednisolona/uso terapéutico , Pirazoles/uso terapéutico , Pirimidinas , Piel/patología , Trombocitemia Esencial/complicaciones , Vasculitis Leucocitoclástica Cutánea/tratamiento farmacológicoRESUMEN
The purpose of this retrospective study was to determine the reasons for consultation in a Dermatology Venereology Department in Cotonou, Benin. A total of 1,070 new patients were included. The main reason for consultation was immunoallergic dermatosis.
Asunto(s)
Dermatitis/epidemiología , Derivación y Consulta , Adulto , Benin/epidemiología , Estudios Transversales , Dermatología , Femenino , Humanos , Masculino , Estudios Retrospectivos , Automedicación/estadística & datos numéricos , VenereologíaRESUMEN
The objective of our study was to evaluate the medico-surgical management of Buruli ulcer (BU) in the BU Screening and Treatment Center (CDTUB) of Allada in Benin. This retrospective and descriptive study retrospectively reviewed records of patients seen from 2010 to 2014 at the CDTUB of Allada. It included patients diagnosed with BU according to WHO epidemiological and clinical criteria as well as laboratory results and who were treated according to WHO medical and surgical recommendations. In all, 274 patients were diagnosed and treated, 57.7% of them children younger than 15 years. Ulcerative lesions (189, 69%) and WHO category II lesions (144, 52.5%) predominated. All patients received dual antibiotic therapy and 43.4% (119) underwent surgery as well. Category III lesions and multifocal lesions required more surgery, whereas most category I lesions healed under medical treatment. The overall rate of healing was 92%: 53.3% for patients who received only antibiotic therapy and 38.7% for those who also had surgery. The median healing time was 13 weeks and ranged from 4 to 56 weeks. In the CDTUB of Allada, between 2010 and 2014, most patients were treated with antibiotic therapy alone, but a significant number still received surgery.
Asunto(s)
Antibacterianos/uso terapéutico , Úlcera de Buruli/tratamiento farmacológico , Úlcera de Buruli/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Benin , Niño , Preescolar , Terapia Combinada , Femenino , Humanos , Lactante , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Factores de Tiempo , Adulto JovenRESUMEN
Hookworm-related cutaneous larva migrans is caused by the subcutaneous migration of hookworm larvae. The characteristic sign is a serpiginous cutaneous track. Folliculitis is an uncommon clinical manifestation. We report a case of hookworm-related folliculitis in a woman performing skin bleaching. A 33-year-old woman presented with a widespread cutaneous eruption made of erythematous and itchy follicular papulo-nodules, with erythematous serpiginous tracks, about 5-10cm long and numerous streaks of scratching, located on the limbs, buttocks and trunk. The cutaneous lesions occurred two days after contact with the floor of a warehouse contamined by faeces of cats. The lesions have been evolving for a week and have been treated with antibiotics without success. Clinical examination found cutaneous atrophy, purple stretch marks and hyperpigmentation of dorsal parts of fingers joints. The patient reported having been using bleaching cosmetics containing topical steroids and hydroquinone for twelve years. She was cured within 4 weeks with oral albendazole 400mg per day during 7 consecutive days.
La folliculite ankylostomienne est une forme folliculaire de larva migrans cutanée ankylostomienne rarement observée. Nous en rapportons un cas chez une patiente de 33 ans, se dépigmentant depuis 12 ans. Elle a consulté pour une éruption évoluant depuis une semaine, diffuse, très prurigineuse, apparue deux jours après le contact avec le sol d'un entrepôt souillé par des déjections de chats. L'examen physique retrouvait de nombreuses lésions de folliculites, érythémateuses coexistant avec des cordons serpigineux de dermatite rampante sur les zones d'extension des membres, le dos, les fesses et l'abdomen, typiques de folliculite ankylostomienne. Un traitement à base d'albendazole 400 mg par jour pendant 7 jours a permis d'obtenir la guérison.
Asunto(s)
Ancylostomatoidea , Foliculitis/parasitología , Larva Migrans/diagnóstico , Preparaciones para Aclaramiento de la Piel , Adulto , Albendazol/uso terapéutico , Animales , Antihelmínticos , Benin , Gatos , Heces/parasitología , Femenino , Humanos , Larva Migrans/tratamiento farmacológico , Larva Migrans/etiologíaAsunto(s)
Infecciones Oportunistas Relacionadas con el SIDA/tratamiento farmacológico , Fármacos Anti-VIH/uso terapéutico , Molusco Contagioso/tratamiento farmacológico , Infecciones Oportunistas Relacionadas con el SIDA/diagnóstico , Adulto , Benin , Quimioterapia Combinada , Femenino , Seropositividad para VIH/diagnóstico , Seropositividad para VIH/tratamiento farmacológico , Humanos , Lamivudine/uso terapéutico , Molusco Contagioso/diagnóstico , Nevirapina/uso terapéutico , Estavudina/uso terapéuticoRESUMEN
Le pityriasis versicolor (PV) est une pathologie cutanée fréquemment rencontrée en consultation dermatologique, surtout dans les pays à climat tropical. Une étude épidémio-clinique, s'intéressant aussi aux comorbidités associées et au retentissement de la maladie a été réalisée. Elle a concerné 118 patients venus consulter dans le service de Dermatologie-Vénérologie au Centre Hospitalier Universitaire Départemental Borgou-Alibori, Bénin. La population la plus touchée était les sujets jeunes avec une fréquence plus élevée chez les 20-30 ans (38,98%). L'âge moyen était de 27,03 ans avec une sex ratio à 1,40. Les antécédents familiaux de pityriasis versicolor ont été retrouvés chez 10 patients soit 8,47%. Comme facteurs favorisants, 57,62% utilisaient les laits corporels dépigmentants. La forme classique (20,37%) était majoritairement représentée. L'acné a été notée chez 19 patients (16,10%). La sérologie VIH était revenue positive chez 4 patients (5,55%) et le diabète a été diagnostiqué chez 3 patients (7,5%). Une altération de la qualité de vie des sujets (35,59%) a été retrouvée.
Pityriasis versicolor (PV) is a cutaneous pathology frequently encountered in dermatological consultations, especially in countries with a tropical climate. An epidemio-clinical study, also questioning the associated comorbidities and the repercussions of the disease, was carried out on 118 patients who came to the Dermatology-Venerology Department at the Borgou-Alibori Departmental University Hospital, Benin. The most affected population was young subjects with a higher frequency in the 20-30 years old (38.98%). The mean age was 27.03 years with a sex ratio of 1.40. Family history was found in 10 patients (8.47%). As contributing factors, 57.62% used depigmenting body milks. The classic form (20.37%) was predominantly represented. Acne was noted in 19 patients (16.10%). HIV serology was positive in 4 patients (5.55%) and diabetes was dignosed in 3 patients (7.5%). A slight alteration in the quality of life of the subjects (35.59%) was found.
Asunto(s)
Humanos , Masculino , Femenino , Calidad de Vida , Signos y Síntomas , Tiña Versicolor , Epidemiología , Infecciones por VIHRESUMEN
OBJECTIVE: The aim of this work was to study the profile of immune and allergic dermatoses (IAD) in children consulting at the outpatient dermatology clinic at the National University Hospital in Cotonou (Benin). METHOD: This retrospective descriptive study examined records of children consulting with this diagnosis over a 10-year period. RESULTS: IAD (902 cases, 37%) were the most common pediatric dermatosis, followed by infectious dermatosis (24%). The sex ratio of children was 0.78. The age groups most strongly affected were those aged 1-30 months (25.39%) and 150-180 months (19.73%). The main IAD were: eczema (47.9%) and prurigo simplex (40.7%). Other IADs included lichen planus (5.1%), toxicoderma (3.8%), urticaria (1.5%), and erythrodermic eczema (1%). The incidence of eczema increased from 13.5% in 2000 to 21.5% in 2009, an increase of 62.2% over 10 years. CONCLUSION: IADs are common at the Cotonou hospital clinic and are dominated by eczema, the incidence of which has increased significantly over time.
Asunto(s)
Hipersensibilidad/epidemiología , Enfermedades del Sistema Inmune/epidemiología , Enfermedades de la Piel/epidemiología , Enfermedades de la Piel/inmunología , Adolescente , Instituciones de Atención Ambulatoria , Benin , Niño , Preescolar , Dermatología , Femenino , Humanos , Lactante , Masculino , Estudios RetrospectivosRESUMEN
BACKGROUND: The objective of this investigation was to study the prevalence of xerosis, eczema, and hair and nail abnormalities in PLWHA in Cotonou. PATIENTS AND METHODS: A retrospective study was performed on the records of PLWHA in Cotonou. All PLWHA with xerosis, eczema, or abnormal appendages were included. RESULTS: Forty-seven patients had xerosis or eczema. Their mean age was 38 years; the sex ratio 0.51 and the mean CD4 count 89 cells/mm(3). Twenty-three patients had xerosis, which affected the whole body (n = 20), lower limb (n = 2), limbs and trunk (n = 1), without gender difference. Twenty-four patients had eczema of which eight had both eczema and xerosis. Forty-two patients had abnormalities of the hair or nails. Their sex ratio was 0.80 and the mean CD4 count 110 cells/mm(3) . Nineteen patients had abnormalities of the hair and scalp: straight hair (n = 16), squamous lesions (n = 2), and folliculitis abscess (n = 1) with a male predominance. Twenty-three patients had nail dermatophytosis (n = 15), candidiasis (n = 7), and ingrowing nails (n = 1). These conditions affected more often women (74%) than men (26%). CONCLUSION: The prevalence of eczema and xerosis is low in our patients. Onychomycosis was the most frequent nail abnormality.
Asunto(s)
Eccema/epidemiología , Cabello/anomalías , Uñas Malformadas/epidemiología , Enfermedades de la Piel/epidemiología , Adulto , Benin/epidemiología , Femenino , Humanos , Masculino , Prevalencia , Estudios RetrospectivosRESUMEN
INTRODUCTION: The aim of this study was to investigate the epidemiological aspects of drug eruptions in children in hospital area in Cotonou. PATIENTS AND METHOD: A retrospective study was carried out in the Department of Dermatology of Cotonou (Benin) from 1998 to 2009. All cases of drug eruption occurred, during the study period, in children under 16 years old were selected for the study. The diagnosis of the drug eruption was based on clinical findings. The Identification of culprit drugs was based on the criteria as defined by the French Group of Pharmaco-vigilance. RESULTS: From 1998 to 2009, 232 cases of drug eruption were diagnosed in the Department of Dermatology. Of this, 35 cases occurred in children under 16 years old. The patient mean age was 6.6 years with a sex ratio of 0.94. 4 patients were HIV positive. The culprit drug was identified in 21 patients (60%): sulfonamides 52.38% (11/21 cases), penicillin 9.52% (2 cases), vaccine 9.52% (2 cases), acetaminophen 9.52% (2 cases), acetyl salicylic acid 4.76% (n = 1), quinine 4.76% (n = 1), phenobarbital 4.76% (n = 1) and ceftriaxone 4.76% (n = 1). The main clinical patterns were: fixed drug eruption 45.71% (16/35), maculopapular rash 17.14% (n = 6), Stevens-Johnson syndrome 17.14% (n=6), and urticaria 8.57% (n = 3), 1 case of toxic epidermal necrolysis was seen and one patient died. CONCLUSION: Skin reactions caused by drug intake are a rare disorder among children and fixed drug eruption is the main clinical presentation of the disease in Cotonou (Benin).
Asunto(s)
Erupciones por Medicamentos/epidemiología , Adolescente , Antibacterianos/efectos adversos , Antiinflamatorios no Esteroideos/efectos adversos , Benin/epidemiología , Niño , Preescolar , Estudios Transversales , Erupciones por Medicamentos/etiología , Eritema/inducido químicamente , Eritema/epidemiología , Exantema/inducido químicamente , Exantema/epidemiología , Femenino , Hospitales Universitarios/estadística & datos numéricos , Humanos , Lactante , Masculino , Estudios Retrospectivos , Síndrome de Stevens-Johnson/epidemiología , Urticaria/inducido químicamente , Urticaria/epidemiología , Vacunas/efectos adversosAsunto(s)
Anetodermia/diagnóstico , Síndrome Antifosfolípido/diagnóstico , Complicaciones del Embarazo/diagnóstico , Aborto Eugénico , Adulto , Anetodermia/sangre , Anetodermia/etiología , Anticuerpos Anticardiolipina/sangre , Anticoagulantes/sangre , Síndrome Antifosfolípido/complicaciones , Femenino , Humanos , Embarazo , Complicaciones del Embarazo/sangre , Complicaciones del Embarazo/etiología , RecurrenciaRESUMEN
Introduction : Les mycoses superficielles sont fréquentes en zones tropicales et représentent le premier motif de consultation en dermatologie dans de nombreux pays africains. Matériel et méthodes : Une étude rétrospective, descriptive et analytique a été réalisée dans le service de Dermatologie du Centre National Hospitalier et Universitaire de Cotonou pour décrire le profil épidémiologique et clinique des mycoses superficielles. Elle a inclus sur 10 ans tous les patients chez qui un diagnostic clinique de mycose superficielle a été retenu. Résultats : La prévalence des mycoses superficielles était de 9,6% (1037/10787 patients). Les deux sexes étaient uniformément représentés et l'âge moyen était de 32,2 ans. Trois groupes cliniques de mycoses superficielles étaient retrouvés : dermatophytoses (44,7%), candidoses cutanéo-muqueuses (32,8%) et pityriasis versicolor (31,3%). Les épidermomycoses (93,4%) étaient réparties en dermatophytoses de la peau glabre et des plis (36,4%), pityriasis versicolor (31,3%) et candidoses des plis (25,7%). Les onychomycoses (9,7%) étaient soit de suspicion candidosique (6,4%) ou soit dermatophytique (3,3%). Les teignes représentaient 5% de l'ensemble des mycoses superficielles et la candidose muqueuse 0,7%. Les principaux facteurs favorisants identifiés étaient l'utilisation abusive des savons antiseptiques (20,4%) et l'usage à visée cosmétique de produits dépigmentants (12,7%). Conclusion : Les mycoses superficielles étaient fréquentes avec une prédominance des épidermomycoses dans le service de dermatologie de Cotonou. Les habitudes cosmétiques représentaient un important facteur favorisant de ces épidermomycoses
Asunto(s)
Benin , Micosis , Tiña , Tiña VersicolorRESUMEN
L'objectif de cette étude était de documenter les aspects épidémiologiques et cliniques du zona en milieu hospitalier à Cotonou. Matériel et méthodes : L'étude était rétrospective et descriptive sur 10 ans et a concerné tous les nouveaux patients reçus en consultation dans le service de Dermatologie du Centre National Hospitalier et Universitaire de Cotonou (CNHU-C), chez qui le diagnostic clinique de zona a été retenu. Résultats : Sur les 10787 nouveaux patients reçus durant la période, 70 présentaient un zona correspondant à une prévalence de 0,6%. Le sex-ratio H/F était de 1,1. La moyenne d'âge était de 42,3 ans avec des extrêmes de 1 an et 73 ans. La tranche d'âge la plus touchée était celle des patients de 50-60 ans. L'infection à VIH était associée au zona dans 46,9% des cas. Les formes érythémato-vésiculeuses à disposition unilatérale étaient prédominantes (79%). Les formes nécrotiques (10%) et nécrotico-hémorragiques (4%) étaient l'apanage des patients infectés par le VIH. Conclusion : Le zona était une dermatose rare dans le service de dermatologie du CNHU- C. L'immunodéficience par le VIH et l'immunosénescence étaient les principaux facteurs de co-morbidité
Asunto(s)
VIH , Benin , Herpes Zóster , InmunosenescenciaRESUMEN
Nous rapportons ici un cas de condylome géant vulvaire chez un nourrisson de 02 ans contaminé par sa « baby-sitter » qui présentait les mêmes lésions. Traité par exérèse chirurgicale couplée à une électrocoagulation, l'évolution a été marquée par une récidive deux semaines après le traitement ; ce qui a nécessité une deuxième séance d'électrocoagulation. Plus d'un an après, plus aucune lésion n'a été notée témoignant ainsi d'un succès thérapeutique. La non disponibilité de l'imiquimod dans notre zone géographique, impose un recours systématique à un traitement invasif quelque soit l'âge du patient
Asunto(s)
África Occidental , Benin , Electrocoagulación , LactanteRESUMEN
Les maladies de peau sont tres frequentes chez les enfants en milieu scolaire. L'objectif de cette enquete est d'apprecier la prevalence des dermatoses en milieu scolaire urbain beninois. Patients et methode : Une etude transversale a ete menee au mois de janvier 2007 a l'Ecole Primaire les `Neems' a Cotonou. L'enquete a concerne tous les ecoliers du Cours d'Initiation au Cours elementaire premiere annee (CE1). Elle a eu lieu au cours de la visite medicale traditionnelle realisee par deux pediatres accredites associes a un dermatologue pour la circonstance .Tous les diagnostics etaient retenus sur la base d'elements cliniques. Les donnees recueillies sont analysees avec EPIINFO version 2002 Le test exact de Fisher a ete utilise pour la comparaison des pourcentages. Resultats Deux cent soixante quatre (264) ecoliers; d'age moyen 7 ans ont ete examines. Le sex-ratio H/F etait de 0;84. Huit dermatoses differentes representant un total de 40 cas ont ete notees a l'examen. soit une prevalence de 15;1. Le prurigo atopique; la xerose et la dermatite atopique representaient plus de 50des cas (n=24); soit une prevalence de 9pour les affections atopiques. Les pathologies infectieuses (n=11) etaient representees par le pityriasis versicolor ; les folliculites superficielles; la teigne et la verrue vulgaire . Leur prevalence etait estimee a 4;1.Il n'y a pas de difference entre les sexes sauf pour le pityriasis versicolor qui a montre une predominance masculine nette (p=0;02). Discussion Cette etude descriptive transversale n'a concerne qu'un nombre limite d'ecoliers; deux cent soixantequatre comparativement a d'autres series [1;2]. Les pathologies allergiques predominaient sur l'ensemble des dermatoses constatees chez les enfants; representant 50des cas des dermatoses repertoriees. Conclusion : Cette etude a revele l'importance des manifestations liees au terrain atopique chez des jeunes ecoliers en milieu urbain beninois