Detalles de la búsqueda
1.
Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology.
Arterioscler Thromb Vasc Biol
; 2024 May 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38695171
2.
Smooth muscle α-actin missense variant promotes atherosclerosis through modulation of intracellular cholesterol in smooth muscle cells.
Eur Heart J
; 44(29): 2713-2726, 2023 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37377039
3.
Stromal ß-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor.
Development
; 147(21)2020 07 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-32541007
4.
Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation.
Arterioscler Thromb Vasc Biol
; 42(8): 1005-1022, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35708026
5.
Resistance of Acta2R149C/+ mice to aortic disease is associated with defective release of mutant smooth muscle α-actin from the chaperonin-containing TCP1 folding complex.
J Biol Chem
; 297(6): 101228, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34600884
6.
Aortic root dilatation and dilated cardiomyopathy in an adult with Tatton-Brown-Rahman syndrome.
Am J Med Genet A
; 188(2): 628-634, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34644003
7.
Expanding ACTA2 genotypes with corresponding phenotypes overlapping with smooth muscle dysfunction syndrome.
Am J Med Genet A
; 188(8): 2389-2396, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35567597
8.
Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response.
Arterioscler Thromb Vasc Biol
; 41(1): 302-316, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33028096
9.
Variants of Unknown Significance in Genes Associated with Heritable Thoracic Aortic Disease Can Be Low Penetrant "Risk Variants".
Am J Hum Genet
; 103(1): 138-143, 2018 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29961567
10.
Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease.
Am J Hum Genet
; 100(1): 21-30, 2017 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27939641
11.
Reversal of Aortic Enlargement Induced by Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction With AT2R Activation.
Arterioscler Thromb Vasc Biol
; 39(3): 459-466, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30602301
12.
Grange syndrome due to homozygous YY1AP1 missense rare variants.
Am J Med Genet A
; 179(12): 2500-2505, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31633303
13.
Loss of Smooth Muscle α-Actin Leads to NF-κB-Dependent Increased Sensitivity to Angiotensin II in Smooth Muscle Cells and Aortic Enlargement.
Circ Res
; 120(12): 1903-1915, 2017 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28461455
14.
Mosaicism for the smooth muscle cell (SMC)-specific knock-in of the Acta2 R179C pathogenic variant: Implications for gene editing therapies.
J Mol Cell Cardiol
; 171: 102-104, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35878552
15.
Overexpression of smooth muscle myosin heavy chain leads to activation of the unfolded protein response and autophagic turnover of thick filament-associated proteins in vascular smooth muscle cells.
J Biol Chem
; 289(20): 14075-88, 2014 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24711452
16.
Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-ß.
Hum Mol Genet
; 22(15): 3123-37, 2013 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23591991
17.
Rare, nonsynonymous variant in the smooth muscle-specific isoform of myosin heavy chain, MYH11, R247C, alters force generation in the aorta and phenotype of smooth muscle cells.
Circ Res
; 110(11): 1411-22, 2012 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22511748
18.
Aortic remodeling after transverse aortic constriction in mice is attenuated with AT1 receptor blockade.
Arterioscler Thromb Vasc Biol
; 33(9): 2172-9, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23868934
19.
Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation.
JCI Insight
; 8(21)2023 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37937642
20.
Nuclear Smooth Muscle α-actin in Vascular Smooth Muscle Cell Differentiation.
Res Sq
; 2023 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36909460