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1.

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials.

Sforzini, Luca; Worrell, Courtney; Kose, Melisa; Anderson, Ian M; Aouizerate, Bruno; Arolt, Volker; Bauer, Michael; Baune, Bernhard T; Blier, Pierre; Cleare, Anthony J; Cowen, Philip J; Dinan, Timothy G; Fagiolini, Andrea; Ferrier, I Nicol; Hegerl, Ulrich; Krystal, Andrew D; Leboyer, Marion; McAllister-Williams, R Hamish; McIntyre, Roger S; Meyer-Lindenberg, Andreas; Miller, Andrew H; Nemeroff, Charles B; Normann, Claus; Nutt, David; Pallanti, Stefano; Pani, Luca; Penninx, Brenda W J H; Schatzberg, Alan F; Shelton, Richard C; Yatham, Lakshmi N; Young, Allan H; Zahn, Roland; Aislaitner, Georgios; Butlen-Ducuing, Florence; Fletcher, Christine; Haberkamp, Marion; Laughren, Thomas; Mäntylä, Fanni-Laura; Schruers, Koen; Thomson, Andrew; Arteaga-Henríquez, Gara; Benedetti, Francesco; Cash-Gibson, Lucinda; Chae, Woo Ri; De Smedt, Heidi; Gold, Stefan M; Hoogendijk, Witte J G; Mondragón, Valeria Jordán; Maron, Eduard; Martynowicz, Jadwiga.

Mol Psychiatry ; 27(3): 1286-1299, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34907394

2.

An integrated approach for establishing dosing recommendations: paliperidone for the treatment of adolescent schizophrenia.

Younis, Islam Rasem; Laughren, Thomas P; Wang, Yaning; Mathis, Mitchell; Gobburu, Jogarao V.

J Clin Psychopharmacol ; 33(2): 152-6, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23422374

3.

Development of a placebo effect model combined with a dropout model for bipolar disorder.

Sun, Wan; Laughren, Thomas P; Zhu, Hao; Hochhaus, Guenther; Wang, Yaning.

J Pharmacokinet Pharmacodyn ; 40(3): 359-68, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23456101

4.

Impact of Obesity on Brexpiprazole Pharmacokinetics: Proposal for Improved Initiation of Treatment.

Bruno, Christopher D; Elmokadem, Ahmed; Housand, Conrad; Jordie, Eric Burroughs; Chow, Christina R; Laughren, Thomas P; Greenblatt, David J.

J Clin Pharmacol ; 62(1): 55-65, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34339048

5.

FDA Perspective on the DSM-5 approach to classification of "cognitive" disorders.

Laughren, Thomas.

J Neuropsychiatry Clin Neurosci ; 23(2): 126-31, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-21677238

6.

Trial design issues and treatment effect modeling in multi-regional schizophrenia trials.

Chen, Yeh-Fong; Wang, Sue-Jane; Khin, Ni A; Hung, H M James; Laughren, Thomas P.

Pharm Stat ; 9(3): 217-29, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-20872622

7.

Assessment of community functioning in people with schizophrenia and other severe mental illnesses: a white paper based on an NIMH-sponsored workshop.

Bellack, Alan S; Green, Michael F; Cook, Judith A; Fenton, Wayne; Harvey, Philip D; Heaton, Robert K; Laughren, Thomas; Leon, Andrew C; Mayo, Donna J; Patrick, Donald L; Patterson, Thomas L; Rose, Andrew; Stover, Ellen; Wykes, Til.

Schizophr Bull ; 33(3): 805-22, 2007 May.

Artículo en Inglés | MEDLINE | ID: mdl-16931542

8.

Suicidality in pediatric patients treated with antidepressant drugs.

Hammad, Tarek A; Laughren, Thomas; Racoosin, Judith.

Arch Gen Psychiatry ; 63(3): 332-9, 2006 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-16520440

9.

Removal from labeling of 60-mg citalopram dose.

Temple, Robert; Laughren, Thomas; Stockbridge, Norman.

Pharmacoepidemiol Drug Saf ; 21(7): 784-786, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22761131

10.

Food and Drug Administration perspective on negative symptoms in schizophrenia as a target for a drug treatment claim.

Laughren, Thomas; Levin, Robert.

Schizophr Bull ; 32(2): 220-2, 2006 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-16079389

11.

Mitigating the Effects of Nonadherence in Clinical Trials.

Shiovitz, Thomas M; Bain, Earle E; McCann, David J; Skolnick, Phil; Laughren, Thomas; Hanina, Adam; Burch, Daniel.

J Clin Pharmacol ; 56(9): 1151-64, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-26634893

12.

Mood disorders in the medically ill: scientific review and recommendations.

Evans, Dwight L; Charney, Dennis S; Lewis, Lydia; Golden, Robert N; Gorman, Jack M; Krishnan, K Ranga Rama; Nemeroff, Charles B; Bremner, J Douglas; Carney, Robert M; Coyne, James C; Delong, Mahlon R; Frasure-Smith, Nancy; Glassman, Alexander H; Gold, Philip W; Grant, Igor; Gwyther, Lisa; Ironson, Gail; Johnson, Robert L; Kanner, Andres M; Katon, Wayne J; Kaufmann, Peter G; Keefe, Francis J; Ketter, Terence; Laughren, Thomas P; Leserman, Jane; Lyketsos, Constantine G; McDonald, William M; McEwen, Bruce S; Miller, Andrew H; Musselman, Dominique; O'Connor, Christopher; Petitto, John M; Pollock, Bruce G; Robinson, Robert G; Roose, Steven P; Rowland, Julia; Sheline, Yvette; Sheps, David S; Simon, Gregory; Spiegel, David; Stunkard, Albert; Sunderland, Trey; Tibbits, Paul; Valvo, William J.

Biol Psychiatry ; 58(3): 175-89, 2005 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-16084838

13.

A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia.

Buchanan, Robert W; Davis, Miriam; Goff, Donald; Green, Michael F; Keefe, Richard S E; Leon, Andrew C; Nuechterlein, Keith H; Laughren, Thomas; Levin, Robert; Stover, Ellen; Fenton, Wayne; Marder, Steve R.

Schizophr Bull ; 31(1): 5-19, 2005 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-15888422

14.

A Growing Crisis in Schizophrenia Drug Development: Failing Signal Detection at North American and Other Clinical Trial Sites.

Laughren, Thomas P.

J Clin Psychiatry ; 81(2)2020 03 03.

Artículo en Inglés | MEDLINE | ID: mdl-32141722

15.

Taking Personalized Medicine Seriously: Biomarker Approaches in Phase IIb/III Studies in Major Depression and Schizophrenia.

Murck, Harald; Laughren, Thomas; Lamers, Femke; Picard, Rosalind; Walther, Sebastian; Goff, Donald; Sainati, Stephen.

Innov Clin Neurosci ; 12(3-4): 26S-40S, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-25977838

16.

Defining therapeutic benefit for people with schizophrenia: focus on negative symptoms.

Schooler, Nina R; Buchanan, Robert W; Laughren, Thomas; Leucht, Stefan; Nasrallah, Henry A; Potkin, Steven G; Abi-Saab, Danielle; Berardo, Carmen Galani; Bugarski-Kirola, Dragana; Blaettler, Thomas; Edgar, Chris J; Nordstroem, Anna-Lena; O'Gorman, Cedric; Garibaldi, George.

Schizophr Res ; 162(1-3): 169-74, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25579053

17.

Developing novel treatments for mood disorders: accelerating discovery.

Tamminga, Carol A; Nemeroff, Charles B; Blakely, Randy D; Brady, Linda; Carter, Cameron S; Davis, Kenneth L; Dingledine, Raymond; Gorman, Jack M; Grigoriadis, Dimitri E; Henderson, David C; B Innis, Robert B; Killen, John; Laughren, Thomas P; McDonald, William M; M Murphy, Greer M; Paul, Steven M; Rudorfer, Matthew V; Sausville, Edward; Schatzberg, Alan F; Scolnick, Edward M; Suppes, Trisha.

Biol Psychiatry ; 52(6): 589-609, 2002 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-12361670

18.

Conventional vs. atypical antipsychotic medications.

Stone, Marc; Racoosin, Judith A; Laughren, Thomas.

N Engl J Med ; 354(9): 972-4; author reply 972-4, 2006 Mar 02.

Artículo en Inglés | MEDLINE | ID: mdl-16514704

19.

Developing strategies for psychopharmacological studies in preschool children.

Greenhill, Laurence L; Jensen, Peter S; Abikoff, Howard; Blumer, Jeffery L; Deveaugh-Geiss, Joseph; Fisher, Celia; Hoagwood, Kimberly; Kratochvil, Christopher J; Lahey, Benjamin B; Laughren, Thomas; Leckman, James; Petti, Theodore A; Pope, Kayla; Shaffer, David; Vitiello, Beneditto; Zeanah, Charles.

J Am Acad Child Adolesc Psychiatry ; 42(4): 406-14, 2003 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-12649627

20.

Methodological issues and controversies in clinical trials with child and adolescent patients with bipolar disorder: report of a consensus conference.

Carlson, Gabrielle A; Jensen, Peter S; Findling, Robert L; Meyer, Roger E; Calabrese, Joseph; DelBello, Melissa P; Emslie, Graham; Flynn, Laurie; Goodwin, Frederick; Hellander, Martha; Kowatch, Robert; Kusumakar, Vivek; Laughren, Thomas; Leibenluft, Ellen; McCracken, James; Nottelmann, Editha; Pine, Daniel; Sachs, Gary; Shaffer, David; Simar, Renee; Strober, Michael; Weller, Elizabeth B; Wozniak, Janet; Youngstrom, Eric A.

J Child Adolesc Psychopharmacol ; 13(1): 13-27, 2003.

Artículo en Inglés | MEDLINE | ID: mdl-12804123

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