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1.

Smart lattice light-sheet microscopy for imaging rare and complex cellular events.

Shi, Yu; Tabet, Jimmy S; Milkie, Daniel E; Daugird, Timothy A; Yang, Chelsea Q; Ritter, Alex T; Giovannucci, Andrea; Legant, Wesley R.

Nat Methods ; 21(2): 301-310, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38167656

2.

Phase separation drives aberrant chromatin looping and cancer development.

Ahn, Jeong Hyun; Davis, Eric S; Daugird, Timothy A; Zhao, Shuai; Quiroga, Ivana Yoseli; Uryu, Hidetaka; Li, Jie; Storey, Aaron J; Tsai, Yi-Hsuan; Keeley, Daniel P; Mackintosh, Samuel G; Edmondson, Ricky D; Byrum, Stephanie D; Cai, Ling; Tackett, Alan J; Zheng, Deyou; Legant, Wesley R; Phanstiel, Douglas H; Wang, Gang Greg.

Nature ; 595(7868): 591-595, 2021 07.

Artículo en Inglés | MEDLINE | ID: mdl-34163069

3.

Deep learning enables fast and dense single-molecule localization with high accuracy.

Speiser, Artur; Müller, Lucas-Raphael; Hoess, Philipp; Matti, Ulf; Obara, Christopher J; Legant, Wesley R; Kreshuk, Anna; Macke, Jakob H; Ries, Jonas; Turaga, Srinivas C.

Nat Methods ; 18(9): 1082-1090, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34480155

4.

3D ATAC-PALM: super-resolution imaging of the accessible genome.

Xie, Liangqi; Dong, Peng; Chen, Xingqi; Hsieh, Tsung-Han S; Banala, Sambashiva; De Marzio, Margherita; English, Brian P; Qi, Yifeng; Jung, Seol Kyoung; Kieffer-Kwon, Kyong-Rim; Legant, Wesley R; Hansen, Anders S; Schulmann, Anton; Casellas, Rafael; Zhang, Bin; Betzig, Eric; Lavis, Luke D; Chang, Howard Y; Tjian, Robert; Liu, Zhe.

Nat Methods ; 17(4): 430-436, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32203384

5.

Applying systems-level spectral imaging and analysis to reveal the organelle interactome.

Valm, Alex M; Cohen, Sarah; Legant, Wesley R; Melunis, Justin; Hershberg, Uri; Wait, Eric; Cohen, Andrew R; Davidson, Michael W; Betzig, Eric; Lippincott-Schwartz, Jennifer.

Nature ; 546(7656): 162-167, 2017 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-28538724

6.

High-density three-dimensional localization microscopy across large volumes.

Legant, Wesley R; Shao, Lin; Grimm, Jonathan B; Brown, Timothy A; Milkie, Daniel E; Avants, Brian B; Lavis, Luke D; Betzig, Eric.

Nat Methods ; 13(4): 359-65, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26950745

7.

Publisher Correction: Deep learning enables fast and dense single-molecule localization with high accuracy.

Speiser, Artur; Müller, Lucas-Raphael; Hoess, Philipp; Matti, Ulf; Obara, Christopher J; Legant, Wesley R; Kreshuk, Anna; Macke, Jakob H; Ries, Jonas; Turaga, Srinivas C.

Nat Methods ; 18(11): 1410, 2021 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-34548656

8.

Cells in the mechanical spotlight.

Hockenberry, Max A; Legant, Wesley R.

Biophys J ; 121(19): 3571-3572, 2022 Oct 04.

Artículo en Inglés | MEDLINE | ID: mdl-36115341

9.

Improving probes for super-resolution.

Moore, Regan P; Legant, Wesley R.

Nat Methods ; 15(9): 659-660, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30171240

10.

Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions.

Legant, Wesley R; Choi, Colin K; Miller, Jordan S; Shao, Lin; Gao, Liang; Betzig, Eric; Chen, Christopher S.

Proc Natl Acad Sci U S A ; 110(3): 881-6, 2013 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-23277584

11.

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels.

Khetan, Sudhir; Guvendiren, Murat; Legant, Wesley R; Cohen, Daniel M; Chen, Christopher S; Burdick, Jason A.

Nat Mater ; 12(5): 458-65, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23524375

12.

A posterior approach to correct for focal plane offsets in lattice light sheet structured illumination microscopy.

Shi, Yu; Daugird, Tim A; Legant, Wesley R.

bioRxiv ; 2024 Apr 26.

Artículo en Inglés | MEDLINE | ID: mdl-38712141

13.

Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment.

Daugird, Timothy A; Shi, Yu; Holland, Katie L; Rostamian, Hosein; Liu, Zhe; Lavis, Luke D; Rodriguez, Joseph; Strahl, Brian D; Legant, Wesley R.

Nat Commun ; 15(1): 4178, 2024 May 16.

Artículo en Inglés | MEDLINE | ID: mdl-38755200

14.

A series of spontaneously blinking dyes for super-resolution microscopy.

Holland, Katie L; Plutkis, Sarah E; Daugird, Timothy A; Sau, Abhishek; Grimm, Jonathan B; English, Brian P; Zheng, Qinsi; Dave, Sandeep; Rahman, Fariha; Xie, Liangqi; Dong, Peng; Tkachuk, Ariana N; Brown, Timothy A; Singer, Robert H; Liu, Zhe; Galbraith, Catherine G; Musser, Siegfried M; Legant, Wesley R; Lavis, Luke D.

bioRxiv ; 2024 Feb 24.

Artículo en Inglés | MEDLINE | ID: mdl-38766149

15.

Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle.

West, Adrian R; Zaman, Nishat; Cole, Darren J; Walker, Matthew J; Legant, Wesley R; Boudou, Thomas; Chen, Christopher S; Favreau, John T; Gaudette, Glenn R; Cowley, Elizabeth A; Maksym, Geoffrey N.

Am J Physiol Lung Cell Mol Physiol ; 304(1): L4-16, 2013 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-23125251

16.

Measurement of mechanical tractions exerted by cells in three-dimensional matrices.

Legant, Wesley R; Miller, Jordan S; Blakely, Brandon L; Cohen, Daniel M; Genin, Guy M; Chen, Christopher S.

Nat Methods ; 7(12): 969-71, 2010 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21076420

17.

A Photopolymerized Hydrogel System with Dual Stiffness Gradients Reveals Distinct Actomyosin-Based Mechano-Responses in Fibroblast Durotaxis.

Hakeem, Reem M; Subramanian, Bhagawat C; Hockenberry, Max A; King, Zayna T; Butler, Mitchell T; Legant, Wesley R; Bear, James E.

ACS Nano ; 17(1): 197-211, 2023 01 10.

Artículo en Inglés | MEDLINE | ID: mdl-36475639

18.

Smart Lattice Light Sheet Microscopy for imaging rare and complex cellular events.

Shi, Yu; Tabet, Jimmy S; Milkie, Daniel E; Daugird, Timothy A; Yang, Chelsea Q; Giovannucci, Andrea; Legant, Wesley R.

bioRxiv ; 2023 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-36945393

19.

Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment.

Daugird, Timothy A; Shi, Yu; Holland, Katie L; Rostamian, Hosein; Liu, Zhe; Lavis, Luke D; Rodriguez, Joseph; Strahl, Brian D; Legant, Wesley R.

bioRxiv ; 2023 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-38014222

20.

Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics.

Doherty, Elizabeth L; Aw, Wen Yih; Warren, Emily C; Hockenberry, Max; Whitworth, Chloe P; Krohn, Grace; Howell, Stefanie; Diekman, Brian O; Legant, Wesley R; Nia, Hadi Tavakoli; Hickey, Anthony J; Polacheck, William J.

Acta Biomater ; 166: 346-359, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37187299

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Smart lattice light-sheet microscopy for imaging rare and complex cellular events.

Phase separation drives aberrant chromatin looping and cancer development.

Deep learning enables fast and dense single-molecule localization with high accuracy.

3D ATAC-PALM: super-resolution imaging of the accessible genome.

Applying systems-level spectral imaging and analysis to reveal the organelle interactome.

High-density three-dimensional localization microscopy across large volumes.

Publisher Correction: Deep learning enables fast and dense single-molecule localization with high accuracy.

Cells in the mechanical spotlight.

Improving probes for super-resolution.

Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions.

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels.

A posterior approach to correct for focal plane offsets in lattice light sheet structured illumination microscopy.

Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment.

A series of spontaneously blinking dyes for super-resolution microscopy.

Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle.

Measurement of mechanical tractions exerted by cells in three-dimensional matrices.

A Photopolymerized Hydrogel System with Dual Stiffness Gradients Reveals Distinct Actomyosin-Based Mechano-Responses in Fibroblast Durotaxis.

Smart Lattice Light Sheet Microscopy for imaging rare and complex cellular events.

Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment.

Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics.