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1.

A flexible approach for predictive biomarker discovery.

Boileau, Philippe; Qi, Nina Ting; van der Laan, Mark J; Dudoit, Sandrine; Leng, Ning.

Biostatistics ; 24(4): 1085-1105, 2023 10 18.

Artículo en Inglés | MEDLINE | ID: mdl-35861622

2.

Practical guidance on modeling choices for the virtual twins method.

Deng, Chuyu; Wolf, Jack M; Vock, David M; Carroll, Dana M; Boatman, Jeffrey A; Hatsukami, Dorothy K; Leng, Ning; Koopmeiners, Joseph S.

J Biopharm Stat ; 33(5): 653-676, 2023 09 03.

Artículo en Inglés | MEDLINE | ID: mdl-36876989

3.

Time-resolved photoconductivity distribution measurement by a synchronized double-scanning method.

Leng, Ning; Ma, Liao; Bai, Ming.

Opt Express ; 30(24): 44095-44102, 2022 Nov 21.

Artículo en Inglés | MEDLINE | ID: mdl-36523092

4.

Real-time imaging of electromagnetic fields.

Ma, Liao; Leng, Ning; Jin, Ming; Bai, Ming.

Opt Express ; 30(12): 20431-20440, 2022 Jun 06.

Artículo en Inglés | MEDLINE | ID: mdl-36224788

5.

SCnorm: robust normalization of single-cell RNA-seq data.

Bacher, Rhonda; Chu, Li-Fang; Leng, Ning; Gasch, Audrey P; Thomson, James A; Stewart, Ron M; Newton, Michael; Kendziorski, Christina.

Nat Methods ; 14(6): 584-586, 2017 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-28418000

6.

Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics.

Barry, Christopher; Schmitz, Matthew T; Argus, Cara; Bolin, Jennifer M; Probasco, Mitchell D; Leng, Ning; Duffin, Bret M; Steill, John; Swanson, Scott; McIntosh, Brian E; Stewart, Ron; Kendziorski, Christina; Thomson, James A; Bacher, Rhonda.

PLoS Comput Biol ; 15(12): e1007543, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31815944

7.

Functional characterization of human pluripotent stem cell-derived arterial endothelial cells.

Zhang, Jue; Chu, Li-Fang; Hou, Zhonggang; Schwartz, Michael P; Hacker, Timothy; Vickerman, Vernella; Swanson, Scott; Leng, Ning; Nguyen, Bao Kim; Elwell, Angela; Bolin, Jennifer; Brown, Matthew E; Stewart, Ron; Burlingham, William J; Murphy, William L; Thomson, James A.

Proc Natl Acad Sci U S A ; 114(30): E6072-E6078, 2017 07 25.

Artículo en Inglés | MEDLINE | ID: mdl-28696312

8.

Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial.

Powles, Thomas; Durán, Ignacio; van der Heijden, Michiel S; Loriot, Yohann; Vogelzang, Nicholas J; De Giorgi, Ugo; Oudard, Stéphane; Retz, Margitta M; Castellano, Daniel; Bamias, Aristotelis; Fléchon, Aude; Gravis, Gwenaëlle; Hussain, Syed; Takano, Toshimi; Leng, Ning; Kadel, Edward E; Banchereau, Romain; Hegde, Priti S; Mariathasan, Sanjeev; Cui, Na; Shen, Xiaodong; Derleth, Christina L; Green, Marjorie C; Ravaud, Alain.

Lancet ; 391(10122): 748-757, 2018 02 24.

Artículo en Inglés | MEDLINE | ID: mdl-29268948

9.

The Transcription Factor Nfatc2 Regulates ß-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.

Keller, Mark P; Paul, Pradyut K; Rabaglia, Mary E; Stapleton, Donnie S; Schueler, Kathryn L; Broman, Aimee Teo; Ye, Shuyun Isabella; Leng, Ning; Brandon, Christopher J; Neto, Elias Chaibub; Plaisier, Christopher L; Simonett, Shane P; Kebede, Melkam A; Sheynkman, Gloria M; Klein, Mark A; Baliga, Nitin S; Smith, Lloyd M; Broman, Karl W; Yandell, Brian S; Kendziorski, Christina; Attie, Alan D.

PLoS Genet ; 12(12): e1006466, 2016 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-27935966

10.

Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.

Cui, Xi-Feng; Cui, Xi-Gang; Leng, Ning.

J Toxicol Pathol ; 32(4): 245-251, 2019 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-31719751

11.

Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments.

Bacher, Rhonda; Leng, Ning; Chu, Li-Fang; Ni, Zijian; Thomson, James A; Kendziorski, Christina; Stewart, Ron.

BMC Bioinformatics ; 19(1): 380, 2018 Oct 16.

Artículo en Inglés | MEDLINE | ID: mdl-30326833

12.

Analysis of embryonic development in the unsequenced axolotl: Waves of transcriptomic upheaval and stability.

Jiang, Peng; Nelson, Jeffrey D; Leng, Ning; Collins, Michael; Swanson, Scott; Dewey, Colin N; Thomson, James A; Stewart, Ron.

Dev Biol ; 426(2): 143-154, 2017 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-27475628

13.

Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments.

Leng, Ning; Chu, Li-Fang; Barry, Chris; Li, Yuan; Choi, Jeea; Li, Xiaomao; Jiang, Peng; Stewart, Ron M; Thomson, James A; Kendziorski, Christina.

Nat Methods ; 12(10): 947-950, 2015 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-26301841

14.

OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data.

Leng, Ning; Choi, Jeea; Chu, Li-Fang; Thomson, James A; Kendziorski, Christina; Stewart, Ron.

Bioinformatics ; 32(9): 1408-10, 2016 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-26743507

15.

EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments.

Leng, Ning; Li, Yuan; McIntosh, Brian E; Nguyen, Bao Kim; Duffin, Bret; Tian, Shulan; Thomson, James A; Dewey, Colin N; Stewart, Ron; Kendziorski, Christina.

Bioinformatics ; 31(16): 2614-22, 2015 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-25847007

16.

The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation.

Smits, Bart M G; Haag, Jill D; Rissman, Anna I; Sharma, Deepak; Tran, Ann; Schoenborn, Alexi A; Baird, Rachael C; Peiffer, Dan S; Leinweber, David Q; Muelbl, Matthew J; Meilahn, Amanda L; Eichelberg, Mark R; Leng, Ning; Kendziorski, Christina; John, Manorama C; Powers, Patricia A; Alexander, Caroline M; Gould, Michael N.

PLoS Genet ; 9(6): e1003549, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23785296

17.

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments.

Leng, Ning; Dawson, John A; Thomson, James A; Ruotti, Victor; Rissman, Anna I; Smits, Bart M G; Haag, Jill D; Gould, Michael N; Stewart, Ron M; Kendziorski, Christina.

Bioinformatics ; 29(8): 1035-43, 2013 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-23428641

18.

Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema.

Stewart, Ron; Rascón, Cynthia Alexander; Tian, Shulan; Nie, Jeff; Barry, Chris; Chu, Li-Fang; Ardalani, Hamisha; Wagner, Ryan J; Probasco, Mitchell D; Bolin, Jennifer M; Leng, Ning; Sengupta, Srikumar; Volkmer, Michael; Habermann, Bianca; Tanaka, Elly M; Thomson, James A; Dewey, Colin N.

PLoS Comput Biol ; 9(3): e1002936, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23505351

19.

Design and measurement of the TE_25,10 mode generator.

Leng, Ning; Jin, Ming; Ma, Liao; Zhang, Yichi; Bai, Ming.

Rev Sci Instrum ; 94(3): 034701, 2023 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-37012757

20.

CD8⁺ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy.

Huseni, Mahrukh A; Wang, Lifen; Klementowicz, Joanna E; Yuen, Kobe; Breart, Beatrice; Orr, Christine; Liu, Li-Fen; Li, Yijin; Gupta, Vinita; Li, Congfen; Rishipathak, Deepali; Peng, Jing; SenbabaoÇ§lu, Yasin; Modrusan, Zora; Keerthivasan, Shilpa; Madireddi, Shravan; Chen, Ying-Jiun; Fraser, Eleanor J; Leng, Ning; Hamidi, Habib; Koeppen, Hartmut; Ziai, James; Hashimoto, Kenji; Fassò, Marcella; Williams, Patrick; McDermott, David F; Rosenberg, Jonathan E; Powles, Thomas; Emens, Leisha A; Hegde, Priti S; Mellman, Ira; Turley, Shannon J; Wilson, Mark S; Mariathasan, Sanjeev; Molinero, Luciana; Merchant, Mark; West, Nathaniel R.

Cell Rep Med ; 4(1): 100878, 2023 01 17.

Artículo en Inglés | MEDLINE | ID: mdl-36599350

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