RESUMEN
OBJECTIVE: To obtain the optimized extraction technology of Paeonia suffruticosa by comparing several extraction method. METHOD: Extract P. suffruticosa by ethanol circumfluence, distillation-decoction, CO2-SFE and traditional decoction, and analyse the results according to the total extraction rate, extraction rate of paeono, extraction of other ingredients and production feasibility. RESULT: Total extraction rates of which are 12.66%, 13.51%, 7.28%, 7.56% respectively; extraction rates of paeonol are 2.45%, 2.26%, 0.31%, 1.15% in turn; Phenolic glycosides can be extracted by ethanol circumfluence, distillation-decoction, traditional decoction, but not by CO2-SFE. CONCLUSION: Distillation-decoction is the most proper extraction technology of P. suffuticosa at present.