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1.

Krebs Cycle Reborn in Macrophage Immunometabolism.

Ryan, Dylan G; O'Neill, Luke A J.

Annu Rev Immunol ; 38: 289-313, 2020 04 26.

Artículo en Inglés | MEDLINE | ID: mdl-31986069

2.

From periphery to center stage: 50 years of advancements in innate immunity.

Carpenter, Susan; O'Neill, Luke A J.

Cell ; 187(9): 2030-2051, 2024 Apr 25.

Artículo en Inglés | MEDLINE | ID: mdl-38670064

3.

Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration.

Jerome, Andrew D; Sas, Andrew R; Wang, Yan; Hammond, Luke A; Wen, Jing; Atkinson, Jeffrey R; Webb, Amy; Liu, Tom; Segal, Benjamin M.

Nat Immunol ; 25(6): 957-968, 2024 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-38811815

4.

Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.

Nuñez, James K; Chen, Jin; Pommier, Greg C; Cogan, J Zachery; Replogle, Joseph M; Adriaens, Carmen; Ramadoss, Gokul N; Shi, Quanming; Hung, King L; Samelson, Avi J; Pogson, Angela N; Kim, James Y S; Chung, Amanda; Leonetti, Manuel D; Chang, Howard Y; Kampmann, Martin; Bernstein, Bradley E; Hovestadt, Volker; Gilbert, Luke A; Weissman, Jonathan S.

Cell ; 184(9): 2503-2519.e17, 2021 04 29.

Artículo en Inglés | MEDLINE | ID: mdl-33838111

5.

An Amygdala Circuit Mediates Experience-Dependent Momentary Arrests during Exploration.

Botta, Paolo; Fushiki, Akira; Vicente, Ana Mafalda; Hammond, Luke A; Mosberger, Alice C; Gerfen, Charles R; Peterka, Darcy; Costa, Rui M.

Cell ; 183(3): 605-619.e22, 2020 10 29.

Artículo en Inglés | MEDLINE | ID: mdl-33031743

6.

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.

Murphy, Michael P; O'Neill, Luke A J.

Cell ; 174(4): 780-784, 2018 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-30096309

7.

Mapping the Genetic Landscape of Human Cells.

Horlbeck, Max A; Xu, Albert; Wang, Min; Bennett, Neal K; Park, Chong Y; Bogdanoff, Derek; Adamson, Britt; Chow, Eric D; Kampmann, Martin; Peterson, Tim R; Nakamura, Ken; Fischbach, Michael A; Weissman, Jonathan S; Gilbert, Luke A.

Cell ; 174(4): 953-967.e22, 2018 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-30033366

8.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley, David A; Dang, Ha X; Zhao, Shuang G; Lloyd, Paul; Aggarwal, Rahul; Alumkal, Joshi J; Foye, Adam; Kothari, Vishal; Perry, Marc D; Bailey, Adina M; Playdle, Denise; Barnard, Travis J; Zhang, Li; Zhang, Jin; Youngren, Jack F; Cieslik, Marcin P; Parolia, Abhijit; Beer, Tomasz M; Thomas, George; Chi, Kim N; Gleave, Martin; Lack, Nathan A; Zoubeidi, Amina; Reiter, Robert E; Rettig, Matthew B; Witte, Owen; Ryan, Charles J; Fong, Lawrence; Kim, Won; Friedlander, Terence; Chou, Jonathan; Li, Haolong; Das, Rajdeep; Li, Hui; Moussavi-Baygi, Ruhollah; Goodarzi, Hani; Gilbert, Luke A; Lara, Primo N; Evans, Christopher P; Goldstein, Theodore C; Stuart, Joshua M; Tomlins, Scott A; Spratt, Daniel E; Cheetham, R Keira; Cheng, Donavan T; Farh, Kyle; Gehring, Julian S; Hakenberg, Jörg; Liao, Arnold; Febbo, Philip G.

Cell ; 174(3): 758-769.e9, 2018 07 26.

Artículo en Inglés | MEDLINE | ID: mdl-30033370

9.

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

Qi, Lei S; Larson, Matthew H; Gilbert, Luke A; Doudna, Jennifer A; Weissman, Jonathan S; Arkin, Adam P; Lim, Wendell A.

Cell ; 184(3): 844, 2021 Feb 04.

Artículo en Inglés | MEDLINE | ID: mdl-33545038

10.

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.

Adamson, Britt; Norman, Thomas M; Jost, Marco; Cho, Min Y; Nuñez, James K; Chen, Yuwen; Villalta, Jacqueline E; Gilbert, Luke A; Horlbeck, Max A; Hein, Marco Y; Pak, Ryan A; Gray, Andrew N; Gross, Carol A; Dixit, Atray; Parnas, Oren; Regev, Aviv; Weissman, Jonathan S.

Cell ; 167(7): 1867-1882.e21, 2016 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-27984733

11.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Mills, Evanna L; Kelly, Beth; Logan, Angela; Costa, Ana S H; Varma, Mukund; Bryant, Clare E; Tourlomousis, Panagiotis; Däbritz, J Henry M; Gottlieb, Eyal; Latorre, Isabel; Corr, Sinéad C; McManus, Gavin; Ryan, Dylan; Jacobs, Howard T; Szibor, Marten; Xavier, Ramnik J; Braun, Thomas; Frezza, Christian; Murphy, Michael P; O'Neill, Luke A.

Cell ; 167(2): 457-470.e13, 2016 Oct 06.

Artículo en Inglés | MEDLINE | ID: mdl-27667687

12.

How Low Cholesterol Is Good for Anti-viral Immunity.

O'Neill, Luke A J.

Cell ; 163(7): 1572-4, 2015 Dec 17.

Artículo en Inglés | MEDLINE | ID: mdl-26687349

13.

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.

Zalatan, Jesse G; Lee, Michael E; Almeida, Ricardo; Gilbert, Luke A; Whitehead, Evan H; La Russa, Marie; Tsai, Jordan C; Weissman, Jonathan S; Dueber, John E; Qi, Lei S; Lim, Wendell A.

Cell ; 160(1-2): 339-50, 2015 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-25533786

14.

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases.

Murphy, Michael P; O'Neill, Luke A J.

Nature ; 626(7998): 271-279, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38326590

15.

Mechanism of single-stranded DNA annealing by RAD52-RPA complex.

Liang, Chih-Chao; Greenhough, Luke A; Masino, Laura; Maslen, Sarah; Bajrami, Ilirjana; Tuppi, Marcel; Skehel, Mark; Taylor, Ian A; West, Stephen C.

Nature ; 629(8012): 697-703, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38658755

16.

Base-editing mutagenesis maps alleles to tune human T cell functions.

Schmidt, Ralf; Ward, Carl C; Dajani, Rama; Armour-Garb, Zev; Ota, Mineto; Allain, Vincent; Hernandez, Rosmely; Layeghi, Madeline; Xing, Galen; Goudy, Laine; Dorovskyi, Dmytro; Wang, Charlotte; Chen, Yan Yi; Ye, Chun Jimmie; Shy, Brian R; Gilbert, Luke A; Eyquem, Justin; Pritchard, Jonathan K; Dodgson, Stacie E; Marson, Alexander.

Nature ; 625(7996): 805-812, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-38093011

17.

Improving prime editing with an endogenous small RNA-binding protein.

Yan, Jun; Oyler-Castrillo, Paul; Ravisankar, Purnima; Ward, Carl C; Levesque, Sébastien; Jing, Yangwode; Simpson, Danny; Zhao, Anqi; Li, Hui; Yan, Weihao; Goudy, Laine; Schmidt, Ralf; Solley, Sabrina C; Gilbert, Luke A; Chan, Michelle M; Bauer, Daniel E; Marson, Alexander; Parsons, Lance R; Adamson, Britt.

Nature ; 628(8008): 639-647, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38570691

18.

Creating ATP via creatine kinase B for NLRP3 activation.

Toller-Kawahisa, Juliana E; O'Neill, Luke A J.

Nat Immunol ; 23(5): 653-655, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35484409

19.

Mitochondria are the powerhouses of immunity.

Mills, Evanna L; Kelly, Beth; O'Neill, Luke A J.

Nat Immunol ; 18(5): 488-498, 2017 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-28418387

20.

A guiding map for inflammation.

Netea, Mihai G; Balkwill, Frances; Chonchol, Michel; Cominelli, Fabio; Donath, Marc Y; Giamarellos-Bourboulis, Evangelos J; Golenbock, Douglas; Gresnigt, Mark S; Heneka, Michael T; Hoffman, Hal M; Hotchkiss, Richard; Joosten, Leo A B; Kastner, Daniel L; Korte, Martin; Latz, Eicke; Libby, Peter; Mandrup-Poulsen, Thomas; Mantovani, Alberto; Mills, Kingston H G; Nowak, Kristen L; O'Neill, Luke A; Pickkers, Peter; van der Poll, Tom; Ridker, Paul M; Schalkwijk, Joost; Schwartz, David A; Siegmund, Britta; Steer, Clifford J; Tilg, Herbert; van der Meer, Jos W M; van de Veerdonk, Frank L; Dinarello, Charles A.

Nat Immunol ; 18(8): 826-831, 2017 Jul 19.

Artículo en Inglés | MEDLINE | ID: mdl-28722720

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