Development of customized implant and customized surgical osteotomy guide in ablative tumor surgery for accurate mandibular reconstruction.

OBJECTIVES: The objective of this study was to provide the generalized methodology for design and development of a customized implant and customized surgical osteotomy guide (CSOG) for precise mandibular tumor resection and placement of a customized implant in ablative tumor surgery for accurate mandibular reconstruction. METHODS: Medical imaging technique, image processing, virtual surgical planning (VSP), biomedical computer-aided design (CAD), and rapid prototyping (RP) were used to develop CSOG and customized implant. A mock surgical test and an experimental analysis were performed on the biomodel (RP assisted diseased model) to check the effectiveness of the CSOG. RESULTS: The paired t test showed the statistically significant result with the use of CSOG as compared to the without using CSOG in ablative mandibular tumor surgery. CONCLUSIONS: A mock test and an experimental analysis proved that, the precise tumor resection and customized implant placement with minimal gap between bone-implant junctions in mandibular reconstruction using CSOG.

Finite element analysis of customized implant in mandibular reconstruction after tumor resection with and without using customized surgical osteotomy guide.

OBJECTIVES: The aim of this work was to compare different 12 cases (3 patients * 4 cases = 12 cases) with varying gaps between implant and bone by analyzing the effect of these gaps on implant and screws using FEM. METHODS: In each patient's case 1 using CSOG and in case 2, 3, and 4 without using CSOG tumor cutting was done. Hence in each patient zero gaps at case 1 and overcutting at case 2, 3, and 4 have obtained at different locations. RESULTS: FEM results reveal that in each patient's case 4 (maximum gap) was more susceptible to loosening of the screws due to higher strains (37%) and implant failure due to higher stress (28%) concentration under the same loading conditions when compared with case 1 (zero gap). CONCLUSIONS: The study reveals that mandibular reconstruction with implant placement using CSOG can significantly enhance the stability and safety of the implant.

Development of an ear cap in chronic suppurative otitis media using additive manufacturing and TRIZ.

The prevalence rate of chronic suppurative otitis media is high and its treatment continues to be a challenge for the otorhinolaryngologists. Due to middle ear infection, there may be pain, hearing loss and spontaneous rupture of the eardrum which results in perforation. Infections can cause a hole in the eardrum as a side effect of otitis media. The patients suffering from ear perforation or having a hole in eardrum require preventing entry of water in the ear. This article describes the development of ear cap using additive manufacturing and TRIZ (a collaborative tool) to prevent the entry of water in the ear during chronic otitis media.

Development of a device to prevent the late consequence of non-treated/lately diagnosed glaucoma.

People residing in rural and remote areas (worldwide) have substantially worse outcome in early detection and diagnosis of glaucoma than those living in metropolitan areas. This gap can be reduced by improved glaucoma diagnosis activities in primary care, but there is little empirical evidence regarding use of tonometry in rural settings, or the expertise associated with quality of eye care. This article describes a feasibility study of a novel through-eyelid tonometer based on the use of an instrumented form of indentation and applanation tonometry.