RESUMEN
Cardiac amyloidosis is an infiltrative abnormality that causes myocardial thickening and dysfunction. Historically, it has been underrecognized as a cause of heart failure and was often misdiagnosed. In the past decade, the cardiology community has improved the understanding of the subtypes of these protein-based infiltrates and how they play a role in heart failure. This article reviews the pathophysiology, presentation, diagnosis, and management of cardiac amyloidosis.
Asunto(s)
Amiloidosis/diagnóstico , Amiloidosis/terapia , Cardiomiopatías/diagnóstico , Cardiomiopatías/terapia , Neuropatías Amiloides Familiares , Amiloidosis/etiología , Amiloidosis/patología , Cardiomiopatías/etiología , Cardiomiopatías/patología , Diagnóstico Diferencial , Errores Diagnósticos/prevención & control , Ecocardiografía , Insuficiencia Cardíaca/etiología , Humanos , Cadenas Ligeras de Inmunoglobulina , Amiloidosis de Cadenas Ligeras de las Inmunoglobulinas , Miocardio/patología , PrealbúminaAsunto(s)
Insuficiencia Cardíaca/diagnóstico , Antagonistas Adrenérgicos beta/uso terapéutico , Adulto , Bloqueo de Rama , Tos/etiología , Diagnóstico Diferencial , Disnea/etiología , Ecocardiografía , Electrocardiografía , Femenino , Furosemida/uso terapéutico , Insuficiencia Cardíaca/complicaciones , Insuficiencia Cardíaca/tratamiento farmacológico , Humanos , Antagonistas de Receptores de Mineralocorticoides/uso terapéutico , Insuficiencia de la Válvula Mitral , Recurrencia , Infecciones del Sistema Respiratorio/diagnóstico , Inhibidores del Simportador de Cloruro Sódico y Cloruro Potásico/uso terapéutico , Volumen SistólicoRESUMEN
Heart failure (HF) is a significant clinical and financial burden worldwide. Remote monitoring (RM) devices capable of identifying early physiologic changes in decompensation have the potential to reduce the HF burden. However, few trials have discussed at length the practical aspects of implementing RM in real-world clinical practice. The present paper reviews current RM devices and clinical trials, focusing on patient populations, outcomes, data collection, storage, and management, and describes the implementation of an RM device in clinical practice, providing a pragmatic and adaptable framework.