1.
Tetrahedron Lett
; 54(32): 4245-4246, 2013 Aug 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-23935222
RESUMEN
An improved method for the synthesis of N1-substituted orotic acid derivatives is reported. The method involves sequential incorporation of nitrogen atoms to the pyrimidine structure from simple starting materials and thus allows the synthesis of N1-substituted orotic acid derivatives with single 15N label at either N-1 or N-3.