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1.
Predictive factors for walking in acute stroke patients: a multicenter study using classification and regression tree analysis.
J Phys Ther Sci
; 35(3): 217-222, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-36866009
2.
Examination of Rehabilitation Intensity According to Severity of Acute Stroke: A Retrospective Study.
J Stroke Cerebrovasc Dis
; 30(9): 105994, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34284324
3.
Factors Influencing Sitting Ability During the Acute Post-Stroke Phase: A Multicenter Prospective Cohort Study in Japan.
J Stroke Cerebrovasc Dis
; 30(1): 105449, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33166768
4.
[Two cases of pulmonary aspergilosis, which deteriorated with generic itraconazole].
Kansenshogaku Zasshi
; 88(4): 469-73, 2014 Jul.
Artículo
en Japonés
| MEDLINE | ID: mdl-25199382
5.
Anti-angiogenic and anti-tumor effects of TAK-593, a potent and selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinase.
Cancer Sci
; 104(4): 486-94, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23305239
6.
Structure-based discovery of cellular-active allosteric inhibitors of FAK.
Bioorg Med Chem Lett
; 23(6): 1779-85, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23414845
7.
Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
Bioorg Med Chem
; 21(24): 7686-98, 2013 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24216091
8.
Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors.
Bioorg Med Chem
; 21(8): 2250-2261, 2013 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23490150
9.
Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics.
Bioorg Med Chem
; 21(15): 4714-29, 2013 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23755884
10.
Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor.
Bioorg Med Chem
; 21(8): 2333-2345, 2013 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23498918
11.
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Nat Genet
; 30(2): 221-6, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-11818964
12.
Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein.
J Biol Chem
; 286(21): 18756-65, 2011 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21454582
13.
A novel pyrrolo[3, 2-d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet-derived growth factor receptor tyrosine kinase inhibitor, shows potent antitumor activity by suppression of tumor angiogenesis.
Cancer Sci
; 103(5): 939-44, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22320850
14.
Design, synthesis, and evaluation of imidazo[1,2-b]pyridazine derivatives having a benzamide unit as novel VEGFR2 kinase inhibitors.
Bioorg Med Chem
; 20(24): 7051-8, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23123015
15.
Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy.
Bioorg Med Chem
; 20(20): 6171-80, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22980219
16.
Usefulness of linezolid in the treatment of hospital-acquired pneumonia caused by MRSA: a prospective observational study.
J Infect Chemother
; 18(2): 160-8, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22041987
17.
Biochemical characterization of TAK-593, a novel VEGFR/PDGFR inhibitor with a two-step slow binding mechanism.
Biochemistry
; 50(5): 738-51, 2011 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-21182308
18.
Biochemical characterization of a novel type-II VEGFR2 kinase inhibitor: comparison of binding to non-phosphorylated and phosphorylated VEGFR2.
Bioorg Med Chem
; 19(18): 5342-51, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21885287
19.
[A case of benign metastasizing leiomyoma medicating for 14 years].
Nihon Kokyuki Gakkai Zasshi
; 49(4): 271-6, 2011 Apr.
Artículo
en Japonés
| MEDLINE | ID: mdl-21591455
20.
Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.
Bioorg Med Chem
; 18(20): 7260-73, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20833055