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1.

Entospletinib with decitabine in acute myeloid leukemia with mutant TP53 or complex karyotype: A phase 2 substudy of the Beat AML Master Trial.

Duong, Vu H; Ruppert, Amy S; Mims, Alice S; Borate, Uma; Stein, Eytan M; Baer, Maria R; Stock, Wendy; Kovacsovics, Tibor; Blum, William; Arellano, Martha L; Schiller, Gary J; Olin, Rebecca L; Foran, James M; Litzow, Mark R; Lin, Tara L; Patel, Prapti A; Foster, Matthew C; Redner, Robert L; Al-Mansour, Zeina; Cogle, Christopher R; Swords, Ronan T; Collins, Robert H; Vergilio, Jo-Anne; Heerema, Nyla A; Rosenberg, Leonard; Yocum, Ashley O; Marcus, Sonja; Chen, Timothy; Druggan, Franchesca; Stefanos, Mona; Gana, Theophilus J; Shoben, Abigail B; Druker, Brian J; Burd, Amy; Byrd, John C; Levine, Ross L; Boyiadzis, Michael M.

Cancer ; 129(15): 2308-2320, 2023 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-37078412

2.

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.

Stein, Eytan M; DiNardo, Courtney D; Fathi, Amir T; Mims, Alice S; Pratz, Keith W; Savona, Michael R; Stein, Anthony S; Stone, Richard M; Winer, Eric S; Seet, Christopher S; Döhner, Hartmut; Pollyea, Daniel A; McCloskey, James K; Odenike, Olatoyosi; Löwenberg, Bob; Ossenkoppele, Gert J; Patel, Prapti A; Roshal, Mikhail; Frattini, Mark G; Lersch, Frederik; Franovic, Aleksandra; Nabhan, Salah; Fan, Bin; Choe, Sung; Wang, Hongfang; Wu, Bin; Hua, Lei; Almon, Caroline; Cooper, Michael; Kantarjian, Hagop M; Tallman, Martin S.

Blood ; 137(13): 1792-1803, 2021 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-33024987

3.

Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.

Roboz, Gail J; DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Mims, Alice S; Prince, Gabrielle T; Altman, Jessica K; Arellano, Martha L; Donnellan, Will; Erba, Harry P; Mannis, Gabriel N; Pollyea, Daniel A; Stein, Anthony S; Uy, Geoffrey L; Watts, Justin M; Fathi, Amir T; Kantarjian, Hagop M; Tallman, Martin S; Choe, Sung; Dai, David; Fan, Bin; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Hickman, Denice; Liu, Hua; Agresta, Samuel V; Wu, Bin; Attar, Eyal C; Stone, Richard M.

Blood ; 135(7): 463-471, 2020 02 13.

Artículo en Inglés | MEDLINE | ID: mdl-31841594

4.

Factors Affecting the Cancer Immunotherapeutic Efficacy of T Cell Bispecific Antibodies and Strategies for Improvement.

Long, Meixiao; Mims, Alice S; Li, Zihai.

Immunol Invest ; 51(8): 2176-2214, 2022 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-36259611

5.

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.

DiNardo, Courtney D; Stein, Eytan M; de Botton, Stéphane; Roboz, Gail J; Altman, Jessica K; Mims, Alice S; Swords, Ronan; Collins, Robert H; Mannis, Gabriel N; Pollyea, Daniel A; Donnellan, Will; Fathi, Amir T; Pigneux, Arnaud; Erba, Harry P; Prince, Gabrielle T; Stein, Anthony S; Uy, Geoffrey L; Foran, James M; Traer, Elie; Stuart, Robert K; Arellano, Martha L; Slack, James L; Sekeres, Mikkael A; Willekens, Christophe; Choe, Sung; Wang, Hongfang; Zhang, Vickie; Yen, Katharine E; Kapsalis, Stephanie M; Yang, Hua; Dai, David; Fan, Bin; Goldwasser, Meredith; Liu, Hua; Agresta, Sam; Wu, Bin; Attar, Eyal C; Tallman, Martin S; Stone, Richard M; Kantarjian, Hagop M.

N Engl J Med ; 378(25): 2386-2398, 2018 Jun 21.

Artículo en Inglés | MEDLINE | ID: mdl-29860938

6.

MRD in AML: who, what, when, where, and how?

Sahasrabudhe, Kieran D; Mims, Alice S.

Blood ; 143(4): 296-298, 2024 Jan 25.

Artículo en Inglés | MEDLINE | ID: mdl-38270942

7.

Treating acute myeloid leukemia in the modern era: A primer.

Blum, William G; Mims, Alice S.

Cancer ; 126(21): 4668-4677, 2020 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-32767757

8.

Preclinical activity and a pilot phase I study of pacritinib, an oral JAK2/FLT3 inhibitor, and chemotherapy in FLT3-ITD-positive AML.

Jeon, Jae Yoon; Zhao, Qiuhong; Buelow, Daelynn R; Phelps, Mitch; Walker, Alison R; Mims, Alice S; Vasu, Sumithira; Behbehani, Gregory; Blachly, James; Blum, William; Klisovic, Rebecca B; Byrd, John C; Garzon, Ramiro; Baker, Sharyn D; Bhatnagar, Bhavana.

Invest New Drugs ; 38(2): 340-349, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31102119

9.

A phase I study of lenalidomide plus chemotherapy with idarubicin and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome.

Saygin, Caner; Larkin, Karilyn; Blachly, James S; Orwick, Shelley; Ngankeu, Apollinaire; Gregory, Charles T; Phelps, Mitch A; Mani, Shylaja; Walker, Alison; Garzon, Ramiro; Vasu, Sumithira; Walsh, Katherine J; Bhatnagar, Bhavana; Klisovic, Rebecca B; Grever, Michael R; Marcucci, Guido; Byrd, John C; Blum, William; Mims, Alice S.

Am J Hematol ; 95(12): 1457-1465, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-32777116

10.

Progress in the problem of relapsed or refractory acute myeloid leukemia.

Mims, Alice S; Blum, William.

Curr Opin Hematol ; 26(2): 88-95, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30640734

11.

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485.

Mims, Alice S; Mishra, Anjali; Orwick, Shelley; Blachly, James; Klisovic, Rebecca B; Garzon, Ramiro; Walker, Alison R; Devine, Steven M; Walsh, Katherine J; Vasu, Sumithira; Whitman, Susan; Marcucci, Guido; Jones, Daniel; Heerema, Nyla A; Lozanski, Gerard; Caligiuri, Michael A; Bloomfield, Clara D; Byrd, John C; Piekarz, Richard; Grever, Michael R; Blum, William.

Haematologica ; 103(6): 982-987, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29567781

12.

Diagnostic utility of bronchoscopy in newly diagnosed acute leukemia patients.

Koenig, Kristin L; Curley, Thomas P; Mani, Shylaja; Keiter, Ashleigh; Zhao, Qiuhong; Behbehani, Gregory K; Bhatnagar, Bhavana; Blachly, James S; Haque, Tamanna Z; Larkin, Karilyn T M; Long, Meixiao; Mims, Alice S; Vasu, Sumithira; Wall, Sarah A; Byrd, John C; Lustberg, Mark; Walker, Alison R; Grieselhuber, Nicole R.

Hematol Oncol ; 40(1): 115-118, 2022 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-34713477

13.

Type of prior genotoxic insult determines the genomic characteristics of therapy-related myeloid neoplasms.

Ozga, Michael; Blachly, James; Eisfeld, Ann-Kathrin; Grieselhuber, Nicole; Larkin, Karilyn; Walker, Alison; Bhatnagar, Bhavana; Behbehani, Gregory; Long, Meixiao; Haque, Tamanna; Vasu, Sumithira; Zhao, Weiqiang; Jones, Daniel; Byrd, John C; Mims, Alice S; Saygin, Caner.

Am J Hematol ; 96(7): E223-E225, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-33761147

14.

Hypomethylating agents super-responders: challenging the dogma of long-term remission for acute myeloid leukemia.

Maakaron, Joseph E; Ozga, Michael P; Mannis, Gabriel N; Pulley, Will; Foster, Matthew C; Zeidner, Joshua F; Mims, Alice S.

Ann Hematol ; 99(6): 1411-1413, 2020 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-32377815

15.

Treating acute myelogenous leukemia in patients aged 70 and above: Recommendations from the International Society of Geriatric Oncology (SIOG).

Extermann, Martine; Artz, Andrew; Rebollo, Maite Antonio; Klepin, Heidi D; Krug, Utz; Loh, Kah Poh; Mims, Alice S; Neuendorff, Nina; Santini, Valeria; Stauder, Reinhard; Vey, Norbert.

J Geriatr Oncol ; 15(2): 101626, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-37741771

16.

Identifying long-term survivors and those at higher or lower risk of relapse among patients with cytogenetically normal acute myeloid leukemia using a high-dimensional mixture cure model.

Archer, Kellie J; Fu, Han; Mrózek, Krzysztof; Nicolet, Deedra; Mims, Alice S; Uy, Geoffrey L; Stock, Wendy; Byrd, John C; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Metzeler, Klaus H; Herold, Tobias; Eisfeld, Ann-Kathrin.

J Hematol Oncol ; 17(1): 28, 2024 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-38702786

17.

The multi-CDK inhibitor dinaciclib reverses bromo- and extra-terminal domain (BET) inhibitor resistance in acute myeloid leukemia via inhibition of Wnt/ß-catenin signaling.

Marr, Alexander R; Halpin, Madeline; Corbin, Dominique L; Asemelash, Yerdanos; Sher, Steven; Gordon, Britten K; Whipp, Ethan C; Mitchell, Shaneice; Harrington, Bonnie K; Orwick, Shelley; Benrashid, Samon; Goettl, Virginia M; Yildiz, Vedat; Mitchell, Andrew D; Cahn, Olivia; Mims, Alice S; Larkin, Karilyn T M; Long, Meixao; Blachly, James; Woyach, Jennifer A; Lapalombella, Rosa; Grieselhuber, Nicole R.

Exp Hematol Oncol ; 13(1): 27, 2024 Mar 04.

Artículo en Inglés | MEDLINE | ID: mdl-38438856

18.

A study to assess the efficacy of enasidenib and risk-adapted addition of azacitidine in newly diagnosed IDH2-mutant AML.

Cai, Sheng F; Huang, Ying; Lance, Jennie R; Mao, Hsiaoyin Charlene; Dunbar, Andrew J; McNulty, Samantha N; Druley, Todd; Li, Yan; Baer, Maria R; Stock, Wendy; Kovacsovics, Tibor; Blum, William G; Schiller, Gary J; Olin, Rebecca L; Foran, James M; Litzow, Mark; Lin, Tara; Patel, Prapti; Foster, Matthew C; Boyiadzis, Michael; Collins, Robert H; Chervin, Jordan; Shoben, Abigail; Vergilio, Jo-Anne; Heerema, Nyla A; Rosenberg, Leonard; Chen, Timothy L; Yocum, Ashley O; Druggan, Franchesca; Marcus, Sonja; Stefanos, Mona; Druker, Brian J; Mims, Alice S; Borate, Uma; Burd, Amy; Byrd, John C; Levine, Ross L; Stein, Eytan M.

Blood Adv ; 8(2): 429-440, 2024 01 23.

Artículo en Inglés | MEDLINE | ID: mdl-37871309

19.

Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia.

Elgamal, Ola A; Fobare, Sydney; Vibhute, Sandip; Mehmood, Abeera; Vroom, Dennis C; Johnson, Mariah L; Stearns, Blaise; Lerma, James R; Truxall, Jean; Stahl, Emily; Carmichael, Bridget; Orwick, Shelley J; Mims, Alice S; Curran, Emily; Santhanam, Ramasamy; Tridandapani, Susheela; Phelps, Mitch A; Xie, Zhiliang; Coss, Christopher C; Baker, Sharyn D; Patrick, Jeffrey; Ezzell, Janel K; Rai, Jayesh; Pan, Jianmin; Rai, Shesh N; Stillwell, Cody; Wunderlich, Mark; Abdulrahim, Mouad; Goodwin, Thomas E; Hilinski, Gerard; Bennett, Chad E; Hertlein, Erin; Byrd, John C.

JCI Insight ; 9(8)2024 Apr 22.

Artículo en Inglés | MEDLINE | ID: mdl-38646934

20.

Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG).

Ozga, Michael; Nicolet, Deedra; Mrózek, Krzysztof; Yilmaz, Ayse S; Kohlschmidt, Jessica; Larkin, Karilyn T; Blachly, James S; Oakes, Christopher C; Buss, Jill; Walker, Christopher J; Orwick, Shelley; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Dufour, Annika; Schneider, Stephanie; Sauerland, Maria Cristina; Görlich, Dennis; Krug, Utz; Berdel, Wolfgang E; Woermann, Bernhard J; Hiddemann, Wolfgang; Braess, Jan; Subklewe, Marion; Spiekermann, Karsten; Carroll, Andrew J; Blum, William G; Powell, Bayard L; Kolitz, Jonathan E; Moore, Joseph O; Mayer, Robert J; Larson, Richard A; Uy, Geoffrey L; Stock, Wendy; Metzeler, Klaus H; Grimes, H Leighton; Byrd, John C; Salomonis, Nathan; Herold, Tobias; Mims, Alice S; Eisfeld, Ann-Kathrin.

Leukemia ; 38(1): 45-57, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-38017103

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