Asunto(s)
Actitud Frente a la Salud/etnología , Grupos Minoritarios/estadística & datos numéricos , Salud de las Minorías/etnología , Neoplasias Cutáneas/epidemiología , Adulto , Negro o Afroamericano/estadística & datos numéricos , Anciano , Pueblo Asiatico/estadística & datos numéricos , Concienciación , Estudios Transversales , Escolaridad , Femenino , Conocimientos, Actitudes y Práctica en Salud , Hispánicos o Latinos/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Ciudad de Nueva York/epidemiología , Características de la Residencia , Neoplasias Cutáneas/diagnóstico , Pigmentación de la Piel , Factores Socioeconómicos , Población Blanca/estadística & datos numéricos , Adulto JovenRESUMEN
Dermatomyositis is an autoimmune condition that results in significant morbidity and mortality through effects on muscle and skin. Corticosteroids are the mainstay of therapy of dermatomyositis, and severe morbidity and mortality occurs in part through the known long-term side effects of chronic steroid use. In addition, dermatomyositis is commonly associated with underlying malignancy, and high-dose steroids may adversely impair treatment of these malignancies. We describe the first use of rapamycin in a young patient with dermatomyositis.
Asunto(s)
Dermatomiositis/tratamiento farmacológico , Inmunosupresores/uso terapéutico , Sirolimus/uso terapéutico , Adulto , Enfermedades Autoinmunes/tratamiento farmacológico , Femenino , Glucocorticoides/administración & dosificación , Humanos , Hipertrigliceridemia/inducido químicamente , Inmunosupresores/efectos adversos , Prednisona/administración & dosificación , Sirolimus/efectos adversosAsunto(s)
Carcinoma/patología , Carcinoma/cirugía , Neoplasias de Cabeza y Cuello/patología , Neoplasias de Cabeza y Cuello/cirugía , Cuero Cabelludo/cirugía , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/cirugía , Negro o Afroamericano , Axila , Carcinoma/secundario , Cejas , Neoplasias Faciales/patología , Neoplasias Faciales/cirugía , Femenino , Humanos , Metástasis Linfática , Masculino , Persona de Mediana Edad , Cirugía de MohsRESUMEN
BACKGROUND: Although it has been established that basal cell carcinoma is an uncommon diagnosis in black patients, the morpheaform subtype is very rare among these individuals. OBJECTIVE: The objective is to present two cases of morpheaform basal cell carcinoma in African-American patients. METHODS: This is a case series and a literature review using the Ovid Medline Database. Key words used in the search include "basal cell carcinoma," "African American," "black," "African," "negros," "morpheaform," "sclerosing," "fibrosing," and "scar-like basal cell carcinoma." The Ovid Medline Database was searched from 1966 to present and was restricted to the English language. RESULTS: A review of the Emory Dermatology clinic charts from 1989 to 2004 revealed two black patients with morpheaform basal cell carcinomas. CONCLUSIONS: Although extremely rare, morpheaform pattern basal cell carcinoma must be considered in the differential diagnosis for black patients presenting with nonhealing lesions.
Asunto(s)
Carcinoma Basocelular/diagnóstico , Neoplasias Cutáneas/diagnóstico , Anciano , Anciano de 80 o más Años , Población Negra , Carcinoma Basocelular/genética , Carcinoma Basocelular/patología , Diagnóstico Diferencial , Femenino , Humanos , Persona de Mediana Edad , Nariz , Neoplasias Cutáneas/genética , Neoplasias Cutáneas/patologíaRESUMEN
We report two cases of lower-extremity furunculosis caused by Mycobacterium mageritense. Both patients were patrons of the same nail salon, where they received footbaths prior to pedicures. M. mageritense bacteria isolated from two whirlpool footbaths were determined to be closely related to the patient isolates by pulsed-field gel electrophoresis.