Detalles de la búsqueda
1.
In vitro potency of xeruborbactam in combination with multiple ß-lactam antibiotics in comparison with other ß-lactam/ß-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum ß-lactamase-producing Enterobacterales.
Antimicrob Agents Chemother
; 67(11): e0044023, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37800963
2.
Intrinsic Antibacterial Activity of Xeruborbactam In Vitro: Assessing Spectrum and Mode of Action.
Antimicrob Agents Chemother
; 66(10): e0087922, 2022 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36102663
3.
In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33782010
4.
In Vitro Activity of the Ultrabroad-Spectrum-Beta-Lactamase Inhibitor QPX7728 against Carbapenem-Resistant Enterobacterales with Varying Intrinsic and Acquired Resistance Mechanisms.
Antimicrob Agents Chemother
; 64(8)2020 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-32482673
5.
In Vitro Activity of the Ultra-Broad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Meropenem against Clinical Isolates of Carbapenem-Resistant Acinetobacter baumannii.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32868334
6.
Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics against Isogenic Strains Expressing Single Beta-Lactamases.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32229489
7.
Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32229498
8.
Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 61(12)2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29038260
9.
Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28848018
10.
Resistance to Ceftazidime-Avibactam Is Due to Transposition of KPC in a Porin-Deficient Strain of Klebsiella pneumoniae with Increased Efflux Activity.
Antimicrob Agents Chemother
; 61(10)2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28739787
11.
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.
Bioorg Med Chem Lett
; 23(5): 1537-43, 2013 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23294697
12.
Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
Bioorg Med Chem Lett
; 21(18): 5171-6, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21831637
13.
Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-ß-lactamases.
J Med Chem
; 63(14): 7491-7507, 2020 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32150407
14.
Comment on "extending applicability of correlation equations to predict colloidal retention in porous media at low fluid velocity".
Environ Sci Technol
; 47(14): 8078-9; discussion 8080-1, 2013 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23777307
15.
Absence of TetB identifies minocycline-susceptible isolates of Acinetobacter baumannii.
Int J Antimicrob Agents
; 52(3): 404-406, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29665446
16.
Comment on particle tracking model for colloid transport near planar surfaces covered with spherical asperities.
Langmuir
; 25(21): 12835-6, 2009 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-19856997
17.
Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines.
J Med Chem
; 57(3): 651-68, 2014 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24428639
18.
Distinguishing on-target versus off-target activity in early antibacterial drug discovery using a macromolecular synthesis assay.
J Biomol Screen
; 18(9): 1018-26, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23686103
19.
Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents.
PLoS One
; 8(12): e84409, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24386374
20.
Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors.
Bioorg Med Chem Lett
; 17(3): 688-91, 2007 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17157005