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1.

E-cigarette vapor renders neutrophils dysfunctional due to filamentous actin accumulation.

Jasper, Alice E; Faniyi, Aduragbemi A; Davis, Lauren C; Grudzinska, Frances S; Halston, Robyn; Hazeldine, Jon; Parekh, Dhruv; Sapey, Elizabeth; Thickett, David R; Scott, Aaron.

J Allergy Clin Immunol ; 153(1): 320-329.e8, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37678576

2.

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study.

Stewart, Iain; Jacob, Joseph; George, Peter M; Molyneaux, Philip L; Porter, Joanna C; Allen, Richard J; Aslani, Shahab; Baillie, J Kenneth; Barratt, Shaney L; Beirne, Paul; Bianchi, Stephen M; Blaikley, John F; Chalmers, James D; Chambers, Rachel C; Chadhuri, Nazia; Coleman, Christopher; Collier, Guilhem; Denneny, Emma K; Docherty, Annemarie; Elneima, Omer; Evans, Rachael A; Fabbri, Laura; Gibbons, Michael A; Gleeson, Fergus V; Gooptu, Bibek; Greening, Neil J; Guio, Beatriz Guillen; Hall, Ian P; Hanley, Neil A; Harris, Victoria; Harrison, Ewen M; Heightman, Melissa; Hillman, Toby E; Horsley, Alex; Houchen-Wolloff, Linzy; Jarrold, Ian; Johnson, Simon R; Jones, Mark G; Khan, Fasihul; Lawson, Rod; Leavy, Olivia; Lone, Nazir; Marks, Michael; McAuley, Hamish; Mehta, Puja; Parekh, Dhruv; Hanley, Karen Piper; Platé, Manuela; Pearl, John; Poinasamy, Krisnah.

Am J Respir Crit Care Med ; 207(6): 693-703, 2023 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-36457159

3.

Cardiovascular Subphenotypes in Acute Respiratory Distress Syndrome.

Chotalia, Minesh; Ali, Muzzammil; Alderman, Joseph E; Bansal, Sukh; Patel, Jaimin M; Bangash, Mansoor N; Parekh, Dhruv.

Crit Care Med ; 51(4): 460-470, 2023 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-36728428

4.

Medium-Term Outcomes in Severely to Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Gautam, Nandan; Madathil, Shyam; Tahani, Natascia; Bolton, Shaun; Parekh, Dhruv; Stockley, James; Goyal, Shraddha; Qureshi, Hannah; Yasmin, Sadhika; Cooper, Brendan G; Short, Jennifer; Geberhiwot, Tarekegn.

Clin Infect Dis ; 74(2): 301-308, 2022 01 29.

Artículo en Inglés | MEDLINE | ID: mdl-33893486

5.

CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome.

Mahida, Rahul Y; Price, Joshua; Lugg, Sebastian T; Li, Hui; Parekh, Dhruv; Scott, Aaron; Harrison, Paul; Matthay, Michael A; Thickett, David R.

Am J Physiol Lung Cell Mol Physiol ; 322(4): L617-L624, 2022 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-35234046

6.

Cigarette smoke exposure and alveolar macrophages: mechanisms for lung disease.

Lugg, Sebastian T; Scott, Aaron; Parekh, Dhruv; Naidu, Babu; Thickett, David R.

Thorax ; 77(1): 94-101, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-33986144

7.

Hyperdynamic Left Ventricular Ejection Fraction in ICU Patients With Sepsis.

Chotalia, Minesh; Ali, Muzzammil; Hebballi, Ravi; Singh, Harjot; Parekh, Dhruv; Bangash, Mansoor N; Patel, Jaimin M.

Crit Care Med ; 50(5): 770-779, 2022 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-34605779

8.

Incidence of Gastrointestinal Bleeding After Transesophageal Echocardiography Use in Orthotopic Liver Transplantation.

Chotalia, Minesh; Topiwala, Upasana; Iqbal, Asim; Parekh, Dhruv; Isaac, John L; Perera, M Thamara P R; Arshad, Mohammed A.

Transpl Int ; 35: 10753, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36338536

9.

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.

Perkins, Gavin D; Ji, Chen; Connolly, Bronwen A; Couper, Keith; Lall, Ranjit; Baillie, J Kenneth; Bradley, Judy M; Dark, Paul; Dave, Chirag; De Soyza, Anthony; Dennis, Anna V; Devrell, Anne; Fairbairn, Sara; Ghani, Hakim; Gorman, Ellen A; Green, Christopher A; Hart, Nicholas; Hee, Siew Wan; Kimbley, Zoe; Madathil, Shyam; McGowan, Nicola; Messer, Benjamin; Naisbitt, Jay; Norman, Chloe; Parekh, Dhruv; Parkin, Emma M; Patel, Jaimin; Regan, Scott E; Ross, Clare; Rostron, Anthony J; Saim, Mohammad; Simonds, Anita K; Skilton, Emma; Stallard, Nigel; Steiner, Michael; Vancheeswaran, Rama; Yeung, Joyce; McAuley, Daniel F.

JAMA ; 327(6): 546-558, 2022 02 08.

Artículo en Inglés | MEDLINE | ID: mdl-35072713

10.

Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome.

Chotalia, Minesh; Ali, Muzzammil; Alderman, Joseph E; Kalla, Manish; Parekh, Dhruv; Bangash, Mansoor N; Patel, Jaimin M.

Crit Care Med ; 49(10): 1757-1768, 2021 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-34224453

11.

Lung function and breathing patterns in hospitalised COVID-19 survivors: a review of post-COVID-19 Clinics.

Stockley, James A; Alhuthail, Eyas A; Coney, Andrew M; Parekh, Dhruv; Geberhiwot, Tarekegn; Gautum, Nandan; Madathil, Shyam C; Cooper, Brendan G.

Respir Res ; 22(1): 255, 2021 Sep 27.

Artículo en Inglés | MEDLINE | ID: mdl-34579722

12.

Renin-angiotensin system inhibitors and susceptibility to COVID-19 in patients with hypertension: a propensity score-matched cohort study in primary care.

Haroon, Shamil; Subramanian, Anuradhaa; Cooper, Jennifer; Anand, Astha; Gokhale, Krishna; Byne, Nathan; Dhalla, Samir; Acosta-Mena, Dionisio; Taverner, Thomas; Okoth, Kelvin; Wang, Jingya; Chandan, Joht Singh; Sainsbury, Christopher; Zemedikun, Dawit Tefra; Thomas, G Neil; Parekh, Dhruv; Marshall, Tom; Sapey, Elizabeth; Adderley, Nicola J; Nirantharakumar, Krishnarajah.

BMC Infect Dis ; 21(1): 262, 2021 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-33722197

13.

Metabolic and Endocrine Challenges.

Martucci, Gennaro; Bonicolini, Eleonora; Parekh, Dhruv; Thein, Onn Shaun; Scherkl, Mario; Amrein, Karin.

Semin Respir Crit Care Med ; 42(1): 78-97, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-32882734

14.

Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial.

Sapey, Elizabeth; Patel, Jaimin M; Greenwood, Hannah; Walton, Georgia M; Grudzinska, Frances; Parekh, Dhruv; Mahida, Rahul Y; Dancer, Rachel C A; Lugg, Sebastian T; Howells, Philip A; Hazeldine, Jon; Newby, Paul; Scott, Aaron; Nightingale, Peter; Hill, Adam T; Thickett, David R.

Am J Respir Crit Care Med ; 200(10): 1282-1293, 2019 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-31206313

15.

Trying to identify who may benefit most from future vitamin D intervention trials: a post hoc analysis from the VITDAL-ICU study excluding the early deaths.

Martucci, Gennaro; McNally, Dayre; Parekh, Dhruv; Zajic, Paul; Tuzzolino, Fabio; Arcadipane, Antonio; Christopher, Kenneth B; Dobnig, Harald; Amrein, Karin.

Crit Care ; 23(1): 200, 2019 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-31164148

16.

ResolvinD₁ stimulates epithelial wound repair and inhibits TGF-ß-induced EMT whilst reducing fibroproliferation and collagen production.

Zheng, Shengxing; Wang, Qian; D'Souza, Vijay; Bartis, Dom; Dancer, Rachel; Parekh, Dhruv; Gao, Fang; Lian, Qingquan; Jin, Shengwei; Thickett, David R.

Lab Invest ; 98(1): 130-140, 2018 01.

Artículo en Inglés | MEDLINE | ID: mdl-29083412

17.

Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages.

Scott, Aaron; Lugg, Sebastian T; Aldridge, Kerrie; Lewis, Keir E; Bowden, Allen; Mahida, Rahul Y; Grudzinska, Frances Susanna; Dosanjh, Davinder; Parekh, Dhruv; Foronjy, Robert; Sapey, Elizabeth; Naidu, Babu; Thickett, David R.

Thorax ; 73(12): 1161-1169, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30104262

18.

The authors reply.

Chotalia, Minesh; Patel, Jaimin M; Parekh, Dhruv; Bangash, Mansoor N.

Crit Care Med ; 51(2): e66-e67, 2023 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-36661470

19.

Vitamin D to Prevent Lung Injury Following Esophagectomy-A Randomized, Placebo-Controlled Trial.

Parekh, Dhruv; Dancer, Rachel C A; Scott, Aaron; D'Souza, Vijay K; Howells, Phillip A; Mahida, Rahul Y; Tang, Jonathan C Y; Cooper, Mark S; Fraser, William D; Tan, LamChin; Gao, Fang; Martineau, Adrian R; Tucker, Olga; Perkins, Gavin D; Thickett, David R.

Crit Care Med ; 46(12): e1128-e1135, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30222631

20.

Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin.

Sapey, Elizabeth; Patel, Jaimin M; Greenwood, Hannah L; Walton, Georgia M; Hazeldine, Jon; Sadhra, Charendeep; Parekh, Dhruv; Dancer, Rachel C A; Nightingale, Peter; Lord, Janet M; Thickett, David R.

Am J Respir Crit Care Med ; 196(10): 1325-1336, 2017 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-28657793

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