Búsqueda | Portal de Búsqueda de la BVS Ecuador

1.

Directed evolution of colE1 plasmid replication compatibility: a fast tractable tunable model for investigating biological orthogonality.

Chaillou, Santiago; Stamou, Pinelopi-Eleftheria; Torres, Leticia L; Riesco, Ana B; Hazelton, Warren; Pinheiro, Vitor B.

Nucleic Acids Res ; 50(16): 9568-9579, 2022 09 09.

Artículo en Inglés | MEDLINE | ID: mdl-36018798

2.

Catalysts from synthetic genetic polymers.

Taylor, Alexander I; Pinheiro, Vitor B; Smola, Matthew J; Morgunov, Alexey S; Peak-Chew, Sew; Cozens, Christopher; Weeks, Kevin M; Herdewijn, Piet; Holliger, Philipp.

Nature ; 518(7539): 427-30, 2015 Feb 19.

Artículo en Inglés | MEDLINE | ID: mdl-25470036

3.

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.

Vanmeert, Michiel; Razzokov, Jamoliddin; Mirza, Muhammad Usman; Weeks, Stephen D; Schepers, Guy; Bogaerts, Annemie; Rozenski, Jef; Froeyen, Mathy; Herdewijn, Piet; Pinheiro, Vitor B; Lescrinier, Eveline.

Nucleic Acids Res ; 47(13): 7130-7142, 2019 07 26.

Artículo en Inglés | MEDLINE | ID: mdl-31334814

4.

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.

Renders, Marleen; Dumbre, Shrinivas; Abramov, Mikhail; Kestemont, Donaat; Margamuljana, Lia; Largy, Eric; Cozens, Christopher; Vandenameele, Julie; Pinheiro, Vitor B; Toye, Dominique; Frère, Jean-Marie; Herdewijn, Piet.

Nucleic Acids Res ; 47(5): 2160-2168, 2019 03 18.

Artículo en Inglés | MEDLINE | ID: mdl-30698800

5.

Bacterial Cell Display as a Robust and Versatile Platform for Engineering Low-Affinity Ligands and Enzymes.

Csibra, Eszter; Renders, Marleen; Pinheiro, Vitor B.

Chembiochem ; 21(19): 2844-2853, 2020 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-32413179

6.

Darwin Assembly: fast, efficient, multi-site bespoke mutagenesis.

Cozens, Christopher; Pinheiro, Vitor B.

Nucleic Acids Res ; 46(8): e51, 2018 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-29409059

7.

Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers.

Liu, Chao; Cozens, Christopher; Jaziri, Faten; Rozenski, Jef; Maréchal, Amandine; Dumbre, Shrinivas; Pezo, Valérie; Marlière, Philippe; Pinheiro, Vitor B; Groaz, Elisabetta; Herdewijn, Piet.

J Am Chem Soc ; 140(21): 6690-6699, 2018 05 30.

Artículo en Inglés | MEDLINE | ID: mdl-29722977

8.

Methylated Nucleobases: Synthesis and Evaluation for Base Pairing InâVitro and InâVivo.

Jabgunde, Amit M; Jaziri, Faten; Bande, Omprakash; Froeyen, Matheus; Abramov, Mikhail; Nguyen, Hoai; Schepers, Guy; Lescrinier, Eveline; Pinheiro, Vitor B; Pezo, Valérie; Marlière, Philippe; Herdewijn, Piet.

Chemistry ; 24(48): 12695-12707, 2018 Aug 27.

Artículo en Inglés | MEDLINE | ID: mdl-29883012

9.

Selection platforms for directed evolution in synthetic biology.

Tizei, Pedro A G; Csibra, Eszter; Torres, Leticia; Pinheiro, Vitor B.

Biochem Soc Trans ; 44(4): 1165-75, 2016 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-27528765

10.

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.

Vanmeert, Michiel; Razzokov, Jamoliddin; Mirza, Muhammad Usman; Weeks, Stephen D; Schepers, Guy; Bogaerts, Annemie; Rozenski, Jef; Froeyen, Mathy; Herdewijn, Piet; Pinheiro, Vitor B; Lescrinier, Eveline.

Nucleic Acids Res ; 47(22): 11976-11977, 2019 12 16.

Artículo en Inglés | MEDLINE | ID: mdl-31713624

11.

Catalysing mirror life.

Renders, Marleen; Pinheiro, Vitor B.

Chembiochem ; 16(6): 899-901, 2015 Apr 13.

Artículo en Inglés | MEDLINE | ID: mdl-25739380

12.

Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo.

Bande, Omprakash; Abu El Asrar, Rania; Braddick, Darren; Dumbre, Shrinivas; Pezo, Valérie; Schepers, Guy; Pinheiro, Vitor B; Lescrinier, Eveline; Holliger, Philipp; Marlière, Philippe; Herdewijn, Piet.

Chemistry ; 21(13): 5009-22, 2015 Mar 23.

Artículo en Inglés | MEDLINE | ID: mdl-25684598

13.

Synthetic polymers and their potential as genetic materials.

Pinheiro, Vitor B; Loakes, David; Holliger, Philipp.

Bioessays ; 35(2): 113-22, 2013 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-23281109

14.

A short adaptive path from DNA to RNA polymerases.

Cozens, Christopher; Pinheiro, Vitor B; Vaisman, Alexandra; Woodgate, Roger; Holliger, Philipp.

Proc Natl Acad Sci U S A ; 109(21): 8067-72, 2012 May 22.

Artículo en Inglés | MEDLINE | ID: mdl-22566643

15.

Rational evolution for altering the ligand preference of estrogen receptor alpha.

Eerlings, Roy; Gupta, Purvi; Lee, Xiao Yin; Nguyen, Tien; El Kharraz, Sarah; Handle, Florian; Smeets, Elien; Moris, Lisa; Devlies, Wout; Vandewinkel, Bram; Thiry, Irina; Ta, Duy Tien; Gorkovskiy, Anton; Voordeckers, Karin; Henckaerts, Els; Pinheiro, Vitor B; Claessens, Frank; Verstrepen, Kevin J; Voet, Arnout; Helsen, Christine.

Protein Sci ; 33(4): e4940, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38511482

16.

Fast quantification of gut bacterial species in cocultures using flow cytometry and supervised classification.

van de Velde, Charlotte C; Joseph, Clémence; Biclot, Anaïs; Huys, Geert R B; Pinheiro, Vitor B; Bernaerts, Kristel; Raes, Jeroen; Faust, Karoline.

ISME Commun ; 2(1): 40, 2022 Apr 25.

Artículo en Inglés | MEDLINE | ID: mdl-37938658

17.

A novel framework for engineering protein loops exploring length and compositional variation.

Tizei, Pedro A G; Harris, Emma; Withanage, Shamal; Renders, Marleen; Pinheiro, Vitor B.

Sci Rep ; 11(1): 9134, 2021 04 28.

Artículo en Inglés | MEDLINE | ID: mdl-33911147

18.

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.

Samson, Camille; Legrand, Pierre; Tekpinar, Mustafa; Rozenski, Jef; Abramov, Mikhail; Holliger, Philipp; Pinheiro, Vitor B; Herdewijn, Piet; Delarue, Marc.

Biomolecules ; 10(12)2020 12 08.

Artículo en Inglés | MEDLINE | ID: mdl-33302546

19.

Evolving a polymerase for hydrophobic base analogues.

Loakes, David; Gallego, José; Pinheiro, Vitor B; Kool, Eric T; Holliger, Philipp.

J Am Chem Soc ; 131(41): 14827-37, 2009 Oct 21.

Artículo en Inglés | MEDLINE | ID: mdl-19778048

20.

Engineering-driven biological insights into DNA polymerase mechanism.

Pinheiro, Vitor B.

Curr Opin Biotechnol ; 60: 9-16, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-30502514

Portal de Búsqueda de la BVS Ecuador

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar:

Directed evolution of colE1 plasmid replication compatibility: a fast tractable tunable model for investigating biological orthogonality.

Catalysts from synthetic genetic polymers.

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.

Bacterial Cell Display as a Robust and Versatile Platform for Engineering Low-Affinity Ligands and Enzymes.

Darwin Assembly: fast, efficient, multi-site bespoke mutagenesis.

Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers.

Methylated Nucleobases: Synthesis and Evaluation for Base Pairing InâVitro and InâVivo.

Selection platforms for directed evolution in synthetic biology.

Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins.

Catalysing mirror life.

Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo.

Synthetic polymers and their potential as genetic materials.

A short adaptive path from DNA to RNA polymerases.

Rational evolution for altering the ligand preference of estrogen receptor alpha.

Fast quantification of gut bacterial species in cocultures using flow cytometry and supervised classification.

A novel framework for engineering protein loops exploring length and compositional variation.

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.

Evolving a polymerase for hydrophobic base analogues.

Engineering-driven biological insights into DNA polymerase mechanism.