Detalles de la búsqueda
1.
Novel spiroindoline quinazolinedione derivatives as anticancer agents and potential FLT3 kinase inhibitors.
Bioorg Med Chem
; 90: 117367, 2023 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37348260
2.
In silico screening of c-Met tyrosine kinase inhibitors targeting nucleotide and drug-substrate binding sites of ABCB1 as potential MDR reversal agents.
J Recept Signal Transduct Res
; 42(6): 549-561, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35704515
3.
Anti-COVID-19 and antidiabetic activities of new oleanane and ursane-type triterpenoids from Salvia grossheimii: an in-silico approach.
J Recept Signal Transduct Res
; 42(6): 540-548, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35544359
4.
Type II c-Met inhibitors: molecular insight into crucial interactions for effective inhibition.
Mol Divers
; 26(3): 1411-1423, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-34247323
5.
Imino-2H-Chromene Based Derivatives as Potential Anti-Alzheimer's Agents: Design, Synthesis, Biological Evaluation and in Silico Study.
Chem Biodivers
; 19(1): e202100599, 2022 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-34786830
6.
Rational Design, Synthesis, in Vitro, and in Silico Studies of Chlorophenylquinazolin-4(3H)-One Containing Different Aryl Acetohydrazides as Tyrosinase Inhibitors.
Chem Biodivers
; 19(7): e202100964, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35675562
7.
The natural-based optimization of kojic acid conjugated to different thio-quinazolinones as potential anti-melanogenesis agents with tyrosinase inhibitory activity.
Bioorg Med Chem
; 36: 116044, 2021 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33640246
8.
Anti-melanogenesis and anti-tyrosinase properties of aryl-substituted acetamides of phenoxy methyl triazole conjugated with thiosemicarbazide: Design, synthesis and biological evaluations.
Bioorg Chem
; 114: 104979, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34140181
9.
Dual potent c-Met and ALK inhibitors: from common feature pharmacophore modeling to structure based virtual screening.
J Recept Signal Transduct Res
; 40(4): 357-364, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32126881
10.
Study of the mechanism of action, molecular docking, and dynamics of anticancer terpenoids from Salvia lachnocalyx.
J Recept Signal Transduct Res
; 40(1): 24-33, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31913736
11.
Novel 2-amino-1,4-naphthoquinone hybrids: Design, synthesis, cytotoxicity evaluation and in silico studies.
Bioorg Med Chem
; 28(21): 115718, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33065435
12.
One-pot synthesis of thioxo-tetrahydropyrimidine derivatives as potent ß-glucuronidase inhibitor, biological evaluation, molecular docking and molecular dynamics studies.
Bioorg Med Chem
; 28(7): 115359, 2020 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32098709
13.
Antidiabetic and cytotoxic polyhydroxylated oleanane and ursane type triterpenoids from Salvia grossheimii.
Bioorg Chem
; 104: 104297, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33011536
14.
A Series of Benzylidenes Linked to Hydrazine-1-carbothioamide as Tyrosinase Inhibitors: Synthesis, Biological Evaluation and Structure-Activity Relationship.
Chem Biodivers
; 17(8): e2000285, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32478439
15.
Prediction of cytotoxic activity of a series of 1H-pyrrolo[2,3-b]pyridine derivatives as possible inhibitors of c-Met using molecular fingerprints.
J Recept Signal Transduct Res
; 39(4): 295-303, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-31658862
16.
Metronidazole aryloxy, carboxy and azole derivatives: Synthesis, anti-tumor activity, QSAR, molecular docking and dynamics studies.
Bioorg Med Chem
; 27(2): 305-314, 2019 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30554970
17.
Identification of new potential HIV-1 reverse transcriptase inhibitors by QSAR modeling and structure-based virtual screening.
J Recept Signal Transduct Res
; 38(1): 37-47, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-29254400
18.
Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs.
Saudi Pharm J
; 24(2): 197-212, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27013913
19.
Hit discovery of potential CDK8 inhibitors and analysis of amino acid mutations for cancer therapy through computer-aided drug discovery.
BMC Chem
; 18(1): 73, 2024 Apr 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38615023
20.
A study of the interaction space of two lactate dehydrogenase isoforms (LDHA and LDHB) and some of their inhibitors using proteochemometrics modeling.
BMC Chem
; 17(1): 70, 2023 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37415191