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1.

An antibody that targets cell-surface glucose-regulated protein-78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages.

Gunner, Cory B; Azmoon, Pardis; Mantuano, Elisabetta; Das, Lipsa; Zampieri, Carlotta; Pizzo, Salvatore V; Gonias, Steven L.

J Cell Biochem ; 124(5): 743-752, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-36947703

2.

Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer.

Gopal, Udhayakumar; Pizzo, Salvatore V.

J Cell Physiol ; 236(4): 2352-2363, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-32864780

3.

Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders.

Gonzalez-Gronow, Mario; Gopal, Udhayakumar; Austin, Richard C; Pizzo, Salvatore V.

IUBMB Life ; 73(6): 843-854, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-33960608

4.

Adipose stem cell crosstalk with chemo-residual breast cancer cells: implications for tumor recurrence.

Lyes, Matthew A; Payne, Sturgis; Ferrell, Paul; Pizzo, Salvatore V; Hollenbeck, Scott T; Bachelder, Robin E.

Breast Cancer Res Treat ; 174(2): 413-422, 2019 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-30594967

5.

Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.

Al-Hashimi, Ali A; Lebeau, Paul; Majeed, Fadwa; Polena, Enio; Lhotak, Sárka; Collins, Celeste A F; Pinthus, Jehonathan H; Gonzalez-Gronow, Mario; Hoogenes, Jen; Pizzo, Salvatore V; Crowther, Mark; Kapoor, Anil; Rak, Janusz; Gyulay, Gabriel; D'Angelo, Sara; Marchiò, Serena; Pasqualini, Renata; Arap, Wadih; Shayegan, Bobby; Austin, Richard C.

J Biol Chem ; 292(51): 21180-21192, 2017 12 22.

Artículo en Inglés | MEDLINE | ID: mdl-29066620

6.

Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.

Masko, Elizabeth M; Alfaqih, Mahmoud A; Solomon, Keith R; Barry, William T; Newgard, Christopher B; Muehlbauer, Michael J; Valilis, Nikolaos A; Phillips, Tameika E; Poulton, Susan H; Freedland, Alexis R; Sun, Stephanie; Dambal, Shweta K; Sanders, Sergio E; Macias, Everardo; Freeman, Michael R; Dewhirst, Mark W; Pizzo, Salvatore V; Freedland, Stephen J.

Prostate ; 77(5): 446-457, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-27900797

7.

Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains.

Gonzalez-Gronow, Mario; Fiedler, Jenny L; Farias Gomez, Cristian; Wang, Fang; Ray, Rupa; Ferrell, Paul D; Pizzo, Salvatore V.

Biochem Biophys Res Commun ; 490(3): 855-860, 2017 08 26.

Artículo en Inglés | MEDLINE | ID: mdl-28648598

8.

Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro.

Gonzalez-Gronow, Mario; Gomez, Cristian Farias; de Ridder, Gustaaf G; Ray, Rupa; Pizzo, Salvatore V.

J Biol Chem ; 289(36): 25166-76, 2014 Sep 05.

Artículo en Inglés | MEDLINE | ID: mdl-25059665

9.

Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance.

Li, Shenduo; Payne, Sturgis; Wang, Fang; Claus, Peter; Su, Zuowei; Groth, Jeffrey; Geradts, Joseph; de Ridder, Gustaaf; Alvarez, Rebeca; Marcom, Paul Kelly; Pizzo, Salvatore V; Bachelder, Robin E.

Breast Cancer Res ; 17: 91, 2015 Jul 04.

Artículo en Inglés | MEDLINE | ID: mdl-26141457

10.

The voltage-dependent anion channel (VDAC) binds tissue-type plasminogen activator and promotes activation of plasminogen on the cell surface.

Gonzalez-Gronow, Mario; Ray, Rupa; Wang, Fang; Pizzo, Salvatore V.

J Biol Chem ; 288(1): 498-509, 2013 Jan 04.

Artículo en Inglés | MEDLINE | ID: mdl-23161549

11.

The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling.

Ray, Rupa; de Ridder, Gustaaf G; Eu, Jerry P; Paton, Adrienne W; Paton, James C; Pizzo, Salvatore V.

J Biol Chem ; 287(39): 32755-69, 2012 Sep 21.

Artículo en Inglés | MEDLINE | ID: mdl-22851173

12.

The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model.

Caso, Jorge; Masko, Elizabeth M; Ii, Jean A Thomas; Poulton, Susan H; Dewhirst, Mark; Pizzo, Salvatore V; Freedland, Stephen J.

Prostate ; 73(5): 449-54, 2013 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23038057

13.

Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways.

Klink, Joseph C; Tewari, Alok K; Masko, Elizabeth M; Antonelli, Jodi; Febbo, Phillip G; Cohen, Pinchas; Dewhirst, Mark W; Pizzo, Salvatore V; Freedland, Stephen J.

Prostate ; 73(7): 754-62, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23192356

14.

Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen.

Misra, Uma K; Payne, Sturgis; Pizzo, Salvatore V.

J Biol Chem ; 286(2): 1248-59, 2011 Jan 14.

Artículo en Inglés | MEDLINE | ID: mdl-21056970

15.

Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.

Misra, Uma K; Pizzo, Salvatore V.

J Cell Biochem ; 113(5): 1488-500, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22173835

16.

Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer.

Kim, Howard S; Masko, Elizabeth M; Poulton, Susan L; Kennedy, Kelly M; Pizzo, Salvatore V; Dewhirst, Mark W; Freedland, Stephen J.

BJU Int ; 110(7): 1062-9, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22394625

17.

Re-examination of CD91 function in GRP94 (glycoprotein 96) surface binding, uptake, and peptide cross-presentation.

Jockheck-Clark, Angela R; Bowers, Edith V; Totonchy, Mariam B; Neubauer, Julie; Pizzo, Salvatore V; Nicchitta, Christopher V.

J Immunol ; 185(11): 6819-30, 2010 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-21048103

18.

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

Al-Hashimi, Ali A; Caldwell, Jennifer; Gonzalez-Gronow, Mario; Pizzo, Salvatore V; Aboumrad, Danya; Pozza, Lindsay; Al-Bayati, Hiam; Weitz, Jeffrey I; Stafford, Alan; Chan, Howard; Kapoor, Anil; Jacobsen, Donald W; Dickhout, Jeffrey G; Austin, Richard C.

J Biol Chem ; 285(37): 28912-23, 2010 Sep 10.

Artículo en Inglés | MEDLINE | ID: mdl-20605795

19.

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

Al-Hashimi, Ali A; Caldwell, Jennifer; Gonzalez-Gronow, Mario; Pizzo, Salvatore V; Aboumrad, Danya; Pozza, Lindsay; Al-Bayati, Hiam; Weitz, Jeffrey I; Stafford, Alan; Chan, Howard; Kapoor, Anil; Jacobsen, Donald W; Dickhout, Jeffrey G; Austin, Richard C.

J Biol Chem ; 290(48): 28725, 2015 Nov 27.

Artículo en Inglés | MEDLINE | ID: mdl-26614782

20.

The antitumorigenic trifecta.

Mowery, Yvonne M; Pizzo, Salvatore V.

Blood ; 114(9): 1727-8, 2009 Aug 27.

Artículo en Inglés | MEDLINE | ID: mdl-19713480

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An antibody that targets cell-surface glucose-regulated protein-78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages.

Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer.

Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders.

Adipose stem cell crosstalk with chemo-residual breast cancer cells: implications for tumor recurrence.

Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.

Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.

Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains.

Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro.

Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance.

The voltage-dependent anion channel (VDAC) binds tissue-type plasminogen activator and promotes activation of plasminogen on the cell surface.

The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling.

The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model.

Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways.

Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen.

Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.

Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer.

Re-examination of CD91 function in GRP94 (glycoprotein 96) surface binding, uptake, and peptide cross-presentation.

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

The antitumorigenic trifecta.