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1.

Live-attenuated chikungunya virus vaccine.

Ng, Lisa F P; Rénia, Laurent.

Cell ; 187(4): 813-813.e1, 2024 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-38364787

2.

Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.

Asarnow, Daniel; Wang, Bei; Lee, Wen-Hsin; Hu, Yuanyu; Huang, Ching-Wen; Faust, Bryan; Ng, Patricia Miang Lon; Ngoh, Eve Zi Xian; Bohn, Markus; Bulkley, David; Pizzorno, Andrés; Ary, Beatrice; Tan, Hwee Ching; Lee, Chia Yin; Minhat, Rabiatul Adawiyah; Terrier, Olivier; Soh, Mun Kuen; Teo, Frannie Jiuyi; Yeap, Yvonne Yee Chin; Seah, Shirley Gek Kheng; Chan, Conrad En Zuo; Connelly, Emily; Young, Nicholas J; Maurer-Stroh, Sebastian; Renia, Laurent; Hanson, Brendon John; Rosa-Calatrava, Manuel; Manglik, Aashish; Cheng, Yifan; Craik, Charles S; Wang, Cheng-I.

Cell ; 184(12): 3192-3204.e16, 2021 06 10.

Artículo en Inglés | MEDLINE | ID: mdl-33974910

3.

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow.

Schlitzer, Andreas; Sivakamasundari, V; Chen, Jinmiao; Sumatoh, Hermi Rizal Bin; Schreuder, Jaring; Lum, Josephine; Malleret, Benoit; Zhang, Sanqian; Larbi, Anis; Zolezzi, Francesca; Renia, Laurent; Poidinger, Michael; Naik, Shalin; Newell, Evan W; Robson, Paul; Ginhoux, Florent.

Nat Immunol ; 16(7): 718-28, 2015 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-26054720

4.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Takata, Kazuyuki; Kozaki, Tatsuya; Lee, Christopher Zhe Wei; Thion, Morgane Sonia; Otsuka, Masayuki; Lim, Shawn; Utami, Kagistia Hana; Fidan, Kerem; Park, Dong Shin; Malleret, Benoit; Chakarov, Svetoslav; See, Peter; Low, Donovan; Low, Gillian; Garcia-Miralles, Marta; Zeng, Ruizhu; Zhang, Jinqiu; Goh, Chi Ching; Gul, Ahmet; Hubert, Sandra; Lee, Bernett; Chen, Jinmiao; Low, Ivy; Shadan, Nurhidaya Binte; Lum, Josephine; Wei, Tay Seok; Mok, Esther; Kawanishi, Shohei; Kitamura, Yoshihisa; Larbi, Anis; Poidinger, Michael; Renia, Laurent; Ng, Lai Guan; Wolf, Yochai; Jung, Steffen; Önder, Tamer; Newell, Evan; Huber, Tara; Ashihara, Eishi; Garel, Sonia; Pouladi, Mahmoud A; Ginhoux, Florent.

Immunity ; 47(1): 183-198.e6, 2017 07 18.

Artículo en Inglés | MEDLINE | ID: mdl-28723550

5.

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.

Karunarathne, Deshapriya S; Horne-Debets, Joshua M; Huang, Johnny X; Faleiro, Rebecca; Leow, Chiuan Yee; Amante, Fiona; Watkins, Thomas S; Miles, John J; Dwyer, Patrick J; Stacey, Katryn J; Yarski, Michael; Poh, Chek Meng; Lee, Jason S; Cooper, Matthew A; Rénia, Laurent; Richard, Derek; McCarthy, James S; Sharpe, Arlene H; Wykes, Michelle N.

Immunity ; 45(2): 333-45, 2016 08 16.

Artículo en Inglés | MEDLINE | ID: mdl-27533014

6.

Functional and immunological mapping of domains of the reticulocyte binding protein, Plasmodium vivax PvRBP2a.

Tay, Matthew Zirui; Tang, Weiyi; Lee, Wenn-Chyau; Ong, Alice Soh Meoy; Novera, Wisna; Malleret, Benoît; Carissimo, Guillaume; Chacko, Ann-Marie; El-Sahili, Abbas; Lescar, Julien; Fan, Yiping; McGready, Rose M; Chu, Cindy S; Chan, Jerry Kok Yen; Ng, Lisa F P; Russell, Bruce; Nosten, François; Rénia, Laurent.

J Infect Dis ; 2024 Mar 05.

Artículo en Inglés | MEDLINE | ID: mdl-38441336

7.

Extended blood stage sensitivity profiles of Plasmodium cynomolgi to doxycycline and tafenoquine, as a model for Plasmodium vivax.

Christensen, Peter; Cinzah, Rosy; Suwanarusk, Rossarin; Chua, Adeline Chiew Yen; Kaneko, Osamu; Kyle, Dennis E; Aung, Htin Lin; Matheson, Jessica; Bifani, Pablo; Rénia, Laurent; Cook, Gregory M; Snounou, Georges; Russell, Bruce.

Antimicrob Agents Chemother ; 68(5): e0028024, 2024 May 02.

Artículo en Inglés | MEDLINE | ID: mdl-38587391

8.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Takata, Kazuyuki; Kozaki, Tatsuya; Lee, Christopher Zhe Wei; Thion, Morgane Sonia; Otsuka, Masayuki; Lim, Shawn; Utami, Kagistia Hana; Fidan, Kerem; Park, Dong Shin; Malleret, Benoit; Chakarov, Svetoslav; See, Peter; Low, Donovan; Low, Gillian; Garcia-Miralles, Marta; Zeng, Ruizhu; Zhang, Jinqiu; Goh, Chi Ching; Gul, Ahmet; Hubert, Sandra; Lee, Bernett; Chen, Jinmiao; Low, Ivy; Shadan, Nurhidaya Binte; Lum, Josephine; Wei, Tay Seok; Mok, Esther; Kawanishi, Shohei; Kitamura, Yoshihisa; Larbi, Anis; Poidinger, Michael; Renia, Laurent; Ng, Lai Guan; Wolf, Yochai; Jung, Steffen; Önder, Tamer; Newell, Evan; Huber, Tara; Ashihara, Eishi; Garel, Sonia; Pouladi, Mahmoud A; Ginhoux, Florent.

Immunity ; 52(2): 417-418, 2020 Feb 18.

Artículo en Inglés | MEDLINE | ID: mdl-32075730

9.

Pathogenic Th1 responses in CHIKV-induced inflammation and their modulation upon Plasmodium parasites co-infection.

Torres-Ruesta, Anthony; Teo, Teck-Hui; Chan, Yi-Hao; Rénia, Laurent; Ng, Lisa F P.

Immunol Rev ; 294(1): 80-91, 2020 03.

Artículo en Inglés | MEDLINE | ID: mdl-31773780

10.

Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine.

Ward, Kurt E; Christensen, Peter; Racklyeft, Annie; Dhingra, Satish K; Chua, Adeline C Y; Remmert, Caroline; Suwanarusk, Rossarin; Matheson, Jessica; Blackman, Michael J; Kaneko, Osamu; Kyle, Dennis E; Lee, Marcus C S; Moon, Robert W; Snounou, Georges; Rénia, Laurent; Fidock, David A; Russell, Bruce; Bifani, Pablo.

J Infect Dis ; 227(10): 1121-1126, 2023 05 12.

Artículo en Inglés | MEDLINE | ID: mdl-36478252

11.

Variant-specific IgA protects against Omicron infection.

Goh, Yun Shan; Fong, Siew-Wai; Hor, Pei Xiang; Loh, Chiew Yee; Wang, Bei; Salleh, Siti Nazihah Mohd; Ngoh, Eve Zi Xian; Lee, Raphael Tze Chuen; Poh, Xuan Ying; Rao, Suma; Chia, Po Ying; Ong, Sean W X; Lee, Tau Hong; Lim, Clarissa; Teo, Jefanie; Pada, Surinder; Sun, Louisa Jin; Ong, Desmond Luan Seng; Somani, Jyoti; Lee, Eng Sing; Maurer-Stroh, Sebastian; Wang, Cheng-I; Leo, Yee-Sin; Lye, David C; Young, Barnaby Edward; Ng, Lisa F P; Renia, Laurent.

J Infect Dis ; 2023 Nov 23.

Artículo en Inglés | MEDLINE | ID: mdl-37996071

12.

Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID-19) resolves 2 years after infection.

Fong, Siew-Wai; Goh, Yun Shan; Torres-Ruesta, Anthony; Chang, Zi Wei; Chan, Yi-Hao; Neo, Vanessa Kexin; Lee, Bernett; Duan, Kaibo; Amrun, Siti Naqiah; Yeo, Nicholas Kim-Wah; Chen, Hsiuyi V; Tay, Matthew Zirui; Carissimo, Guillaume; Tan, Seow Yen; Leo, Yee-Sin; Lye, David C; Renia, Laurent; Young, Barnaby Edward; Ng, Lisa F P.

J Med Virol ; 95(5): e28774, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37212320

13.

Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.

Rouers, Angeline; Wong, Nathan; Goh, Yun Shan; Torres-Ruesta, Anthony; Tay, Matthew Zirui; Chang, Zi Wei; Fong, Siew-Wai; Neo, Vanessa; Kam, Isaac Kai Jie; Yeo, Nicholas Kim-Wah; Huang, Yuling; Loh, Chiew Yee; Hor, Pei Xiang; Wong, Joel Xu En; Tan, Yong Jie; Macary, Paul A; Qian, Xinlei; Bei, Wang; Ngoh, Eve Zi Xian; Salleh, Siti Nazihah Mohd; Wang, Cheng-I; Poh, Xuan Ying; Rao, Suma; Chia, Po Ying; Ong, Sean W X; Lee, Tau Hong; Lin, Ray J H; Lim, Clarissa; Teo, Jefanie; Ren, Ee Chee; Lye, David Chien; Young, Barnaby E; Ng, Lisa F P; Renia, Laurent.

J Med Virol ; 95(1): e28258, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36305052

14.

Antibody Response of Heterologous vs Homologous Messenger RNA Vaccine Boosters Against the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant: Interim Results from the PRIBIVAC Study, a Randomized Clinical Trial.

Poh, Xuan Ying; Tan, Chee Wah; Lee, I Russel; Chavatte, Jean-Marc; Fong, Siew-Wai; Prince, Tessa; Hartley, Catherine; Yeoh, Aileen Y Y; Rao, Suma; Chia, Po Ying; Ong, Sean W X; Lee, Tau Hong; Sadarangani, Sapna P; Lin, Ray J H; Lim, Clarissa; Teo, Jefanie; Lim, Daniel R X; Chia, Wanni; Hiscox, Julian A; Ng, Lisa F P; Ren, Ee Chee; Lin, Raymond T P; Renia, Laurent; Lye, David Chien; Wang, Lin-Fa; Young, Barnaby E.

Clin Infect Dis ; 75(12): 2088-2096, 2022 12 19.

Artículo en Inglés | MEDLINE | ID: mdl-35543372

15.

Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection.

Fong, Siew-Wai; Yeo, Nicholas Kim-Wah; Chan, Yi-Hao; Goh, Yun Shan; Amrun, Siti Naqiah; Ang, Nicholas; Rajapakse, Menaka Priyadharsani; Lum, Josephine; Foo, Shihui; Lee, Cheryl Yi-Pin; Carissimo, Guillaume; Chee, Rhonda Sin-Ling; Torres-Ruesta, Anthony; Tay, Matthew Zirui; Chang, Zi Wei; Poh, Chek Meng; Young, Barnaby Edward; Tambyah, Paul A; Kalimuddin, Shirin; Leo, Yee-Sin; Lye, David C; Lee, Bernett; Biswas, Subhra; Howland, Shanshan Wu; Renia, Laurent; Ng, Lisa F P.

J Clin Immunol ; 42(2): 214-229, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34716845

16.

Discrepant serological findings in SARS-CoV-2 PCR-negative hospitalized patients with fever and acute respiratory symptoms during the pandemic.

Cross, Gail B; Naftalin, Claire M; Ngiam, Jinghao N; Bagdasarian, Natasha; Poh, Chek M; Goh, Yun S; Chia, Wan N; Amrun, Siti N; Tham, Sai M; Teng, Hazel; Alagha, Rawan; Kumar, Shoban K; Tan, Shaun S Y; Wang, Lin F; Tambyah, Paul A; Renia, Laurent; Fisher, Dale; Ng, Lisa F P.

J Med Virol ; 94(6): 2460-2470, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35171507

17.

Suppression of Plasmodium MIF-CD74 signaling protects against severe malaria.

Baeza Garcia, Alvaro; Siu, Edwin; Du, Xin; Leng, Lin; Franke-Fayard, Blandine; Janse, Chris J; Howland, Shanshan W; Rénia, Laurent; Lolis, Elias; Bucala, Richard.

FASEB J ; 35(12): e21997, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34719814

18.

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses.

Schlitzer, Andreas; McGovern, Naomi; Teo, Pearline; Zelante, Teresa; Atarashi, Koji; Low, Donovan; Ho, Adrian W S; See, Peter; Shin, Amanda; Wasan, Pavandip Singh; Hoeffel, Guillaume; Malleret, Benoit; Heiseke, Alexander; Chew, Samantha; Jardine, Laura; Purvis, Harriet A; Hilkens, Catharien M U; Tam, John; Poidinger, Michael; Stanley, E Richard; Krug, Anne B; Renia, Laurent; Sivasankar, Baalasubramanian; Ng, Lai Guan; Collin, Matthew; Ricciardi-Castagnoli, Paola; Honda, Kenya; Haniffa, Muzlifah; Ginhoux, Florent.

Immunity ; 38(5): 970-83, 2013 May 23.

Artículo en Inglés | MEDLINE | ID: mdl-23706669

19.

Molecular Characterization of MHC Class I Alpha 1 and 2 Domains in Asian Seabass (Lates calcarifer).

Loh, Zhixuan; Huan, Xuelu; Awate, Sunita; Schrittwieser, Markus; Renia, Laurent; Ren, Ee Chee.

Int J Mol Sci ; 23(18)2022 Sep 14.

Artículo en Inglés | MEDLINE | ID: mdl-36142628

20.

PET Imaging of Translocator Protein as a Marker of Malaria-Associated Lung Inflammation.

Goggi, Julian L; Claser, Carla; Hartimath, Siddesh V; Hor, Pei Xiang; Tan, Peng Wen; Ramasamy, Boominathan; Abdul Rahman, Husaini; Cheng, Peter; Chang, Zi Wei; Nguee, Samantha Yee Teng; Tang, Jun Rong; Robins, Edward G; Renia, Laurent.

Infect Immun ; 89(10): e0002421, 2021 09 16.

Artículo en Inglés | MEDLINE | ID: mdl-34251290

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Live-attenuated chikungunya virus vaccine.

Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.

Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.

Functional and immunological mapping of domains of the reticulocyte binding protein, Plasmodium vivax PvRBP2a.

Extended blood stage sensitivity profiles of Plasmodium cynomolgi to doxycycline and tafenoquine, as a model for Plasmodium vivax.

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

Pathogenic Th1 responses in CHIKV-induced inflammation and their modulation upon Plasmodium parasites co-infection.

Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine.

Variant-specific IgA protects against Omicron infection.

Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID-19) resolves 2 years after infection.

Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.

Antibody Response of Heterologous vs Homologous Messenger RNA Vaccine Boosters Against the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant: Interim Results from the PRIBIVAC Study, a Randomized Clinical Trial.

Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection.

Discrepant serological findings in SARS-CoV-2 PCR-negative hospitalized patients with fever and acute respiratory symptoms during the pandemic.

Suppression of Plasmodium MIF-CD74 signaling protects against severe malaria.

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses.

Molecular Characterization of MHC Class I Alpha 1 and 2 Domains in Asian Seabass (Lates calcarifer).

PET Imaging of Translocator Protein as a Marker of Malaria-Associated Lung Inflammation.