Detalles de la búsqueda
1.
Co-Expression Network Analysis Unveiled lncRNA-mRNA Links Correlated to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance and/or Intermediate Epithelial-to-Mesenchymal Transition Phenotypes in a Human Non-Small Cell Lung Cancer Cellular Model System.
Int J Mol Sci
; 25(7)2024 Mar 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38612674
2.
Crystal structures of Schistosoma mansoni histone deacetylase 8 reveal a novel binding site for allosteric inhibitors.
J Biol Chem
; 298(10): 102375, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35970392
3.
Comparative metabolic profiling by 1H-NMR spectroscopy analysis reveals the adaptation of S. mansoni from its host to in vitro culture conditions: a pilot study with ex vivo and GSH-supplemented medium-cultured parasites.
Parasitol Res
; 121(4): 1191-1198, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35024953
4.
In Vitro and In Vivo Effects of the Urokinase Plasminogen Activator Inhibitor WX-340 on Anaplastic Thyroid Cancer Cell Lines.
Int J Mol Sci
; 23(7)2022 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35409084
5.
(+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages.
Bioorg Chem
; 102: 104067, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32663671
6.
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone.
Mar Drugs
; 18(2)2020 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32075136
7.
ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis.
Proc Natl Acad Sci U S A
; 114(50): 13254-13259, 2017 12 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29162693
8.
Chemical Investigation of the Indonesian Tunicate Polycarpa aurata and Evaluation of the Effects Against Schistosoma mansoni of the Novel Alkaloids Polyaurines A and B.
Mar Drugs
; 17(5)2019 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31083316
9.
Effects of structurally distinct human HDAC6 and HDAC6/HDAC8 inhibitors against S. mansoni larval and adult worm stages.
PLoS Negl Trop Dis
; 18(2): e0011992, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38416775
10.
The activity of a PI3K δ-sparing inhibitor, MEN1611, in non-small cell lung cancer cells with constitutive activation of the PI3K/AKT/mTOR pathway.
Front Oncol
; 13: 1283951, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38033496
11.
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
Eur J Med Chem
; 238: 114409, 2022 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35551034
12.
FADD-calmodulin interaction: a novel player in cell cycle regulation.
Biochim Biophys Acta
; 1803(8): 898-911, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20420860
13.
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation.
Eur J Med Chem
; 212: 112998, 2021 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33199154
14.
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
J Med Chem
; 64(14): 9960-9988, 2021 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34251197
15.
Luminescence-Based, Low- and Medium-Throughput Assays for Drug Screening in Schistosoma mansoni Larval Stage.
Methods Mol Biol
; 2151: 219-227, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32452008
16.
Drug effects on metabolic profiles of Schistosoma mansoni adult male parasites detected by 1H-NMR spectroscopy.
PLoS Negl Trop Dis
; 14(10): e0008767, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33044962
17.
Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability.
ACS Infect Dis
; 6(1): 124-137, 2020 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31718145
18.
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents.
ACS Infect Dis
; 6(1): 100-113, 2020 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31661956
19.
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation.
ACS Med Chem Lett
; 11(11): 2268-2276, 2020 Nov 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33214839
20.
The 3' UTR of the human CTLA4 mRNA can regulate mRNA stability and translational efficiency.
Biochim Biophys Acta
; 1779(1): 60-5, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18078835