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1.

Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery.

Krakovka, Sascha; Ranjbarian, Farahnaz; Luján, Lucas A; Saura, Alicia; Larsen, Nicolai B; Jiménez-González, Alejandro; Reggenti, Anna; Luján, Hugo D; Svärd, Staffan G; Hofer, Anders.

J Biol Chem ; 298(6): 102028, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35568200

2.

Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation.

Rodríguez-Walker, Macarena; Molina, Cecilia R; Luján, Lucas A; Saura, Alicia; Jerlström-Hultqvist, Jon; Svärd, Staffan G; Fernández, Elmer A; Luján, Hugo D.

Genomics ; 114(5): 110462, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-35998788

3.

Cytokines, Antibodies, and Histopathological Profiles during Giardia Infection and Variant-Specific Surface Protein-Based Vaccination.

Serradell, Marianela C; Gargantini, Pablo R; Saura, Alicia; Oms, Sergio R; Rupil, Lucía L; Berod, Luciana; Sparwasser, Tim; Luján, Hugo D.

Infect Immun ; 86(6)2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29555679

4.

Antigenic variation in Giardia lamblia is regulated by RNA interference.

Prucca, César G; Slavin, Ileana; Quiroga, Rodrigo; Elías, Eliana V; Rivero, Fernando D; Saura, Alicia; Carranza, Pedro G; Luján, Hugo D.

Nature ; 456(7223): 750-4, 2008 Dec 11.

Artículo en Inglés | MEDLINE | ID: mdl-19079052

5.

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia.

Tenaglia, Albano H; Luján, Lucas A; Ríos, Diego N; Molina, Cecilia R; Midlej, Victor; Iribarren, Paula A; Berazategui, María A; Torri, Alessandro; Saura, Alicia; Peralta, Damián O; Rodríguez-Walker, Macarena; Fernández, Elmer A; Petiti, Juan P; Serradell, Marianela C; Gargantini, Pablo R; Sparwasser, Tim; Alvarez, Vanina E; de Souza, Wanderley; Luján, Hugo D.

Nat Commun ; 14(1): 2537, 2023 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-37137944

6.

A Thermostable Oral SARS-CoV-2 Vaccine Induces Mucosal and Protective Immunity.

Bellier, Bertrand; Saura, Alicia; Luján, Lucas A; Molina, Cecilia R; Luján, Hugo D; Klatzmann, David.

Front Immunol ; 13: 837443, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35281065

7.

ORF-C4 from the early branching eukaryote Giardia lamblia displays characteristics of alpha-crystallin small heat-shock proteins.

Nores, María J; Prucca, César G; Quiroga, Rodrigo; Elías, Eliana V; Cavallín, Lucas; Price, Argenta M; Saura, Alicia; Carranza, Pedro G; Gottig, Natalia; Solari, Alberto J; Lujan, Hugo D.

Biosci Rep ; 29(1): 25-34, 2009 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-18680481

8.

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.

Serradell, Marianela C; Rupil, Lucía L; Martino, Román A; Prucca, César G; Carranza, Pedro G; Saura, Alicia; Fernández, Elmer A; Gargantini, Pablo R; Tenaglia, Albano H; Petiti, Juan P; Tonelli, Renata R; Reinoso-Vizcaino, Nicolás; Echenique, José; Berod, Luciana; Piaggio, Eliane; Bellier, Bertrand; Sparwasser, Tim; Klatzmann, David; Luján, Hugo D.

Nat Commun ; 10(1): 361, 2019 01 21.

Artículo en Inglés | MEDLINE | ID: mdl-30664644

9.

Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia.

Carranza, Pedro G; Gargantini, Pablo R; Prucca, César G; Torri, Alessandro; Saura, Alicia; Svärd, Staffan; Lujan, Hugo D.

Int J Biochem Cell Biol ; 81(Pt A): 32-43, 2016 12.

Artículo en Inglés | MEDLINE | ID: mdl-27771437

10.

Vaccination of domestic animals with a novel oral vaccine prevents Giardia infections, alleviates signs of giardiasis and reduces transmission to humans.

Serradell, Marianela C; Saura, Alicia; Rupil, Lucia L; Gargantini, Pablo R; Faya, Marcela I; Furlan, Paulina J; Lujan, Hugo D.

NPJ Vaccines ; 1: 16018, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-29263857

11.

A unique mechanism of nuclear division in Giardia lamblia involves components of the ventral disk and the nuclear envelope.

Solari, Alberto J; Rahn, Monica I; Saura, Alicia; Lujan, Hugo D.

Biocell ; 27(3): 329-46, 2003 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-15002750

12.

Disruption of antigenic variation is crucial for effective parasite vaccine.

Rivero, Fernando D; Saura, Alicia; Prucca, Cesar G; Carranza, Pedro G; Torri, Alessandro; Lujan, Hugo D.

Nat Med ; 16(5): 551-7, 1p following 557, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20418884

13.

Dephosphorylation of cyst wall proteins by a secreted lysosomal acid phosphatase is essential for excystation of Giardia lamblia.

Slavin, Ileana; Saura, Alicia; Carranza, Pedro G; Touz, María C; Nores, María J; Luján, Hugo D.

Mol Biochem Parasitol ; 122(1): 95-8, 2002 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-12076774

14.

Identification of variant-specific surface proteins in Giardia muris trophozoites.

Ropolo, Andrea S; Saura, Alicia; Carranza, Pedro G; Lujan, Hugo D.

Infect Immun ; 73(8): 5208-11, 2005 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16041041

15.

Nuevos métodos para el diagnóstico microbiológico de la amebiasis y de otros protozoarios intestinales / New methods for the microbiological diagnosis of amebiasis and other intestinal protozoa

Saura, Alicia.

Córdoba; s.n; 2012. 96 p. ilus, ^c29 cm, ^eCD Texto Completo.

Tesis en Español | LILACS | ID: lil-695477

16.

Nuevos métodos para el diagnóstico microbiológico de la amebiasis y de otros protozoarios intestinales / New methods for the microbiological diagnosis of amebiasis and other intestinal protozoa

Saura, Alicia.

Córdoba; s.n; 2012. 96 p. ilus^c29 cm^eCD Texto Completo.

Tesis en Español | BINACIS | ID: bin-128424

17.

Instituciones psiquiátricas en el contexto de la pandemia por COVID-19, 2020 / Psychiatric institutions in the context of the COVID-19 pandemic, 2020

Cheroni, Ariadna; Iglesias, Victoria; Latorre, Laura; Leguizamón, Fernando; Saura, Alicia.

Montevideo; Institución Nacional de Derechos Humanos y Defensoría del Pueblo; 2020. 67 p. ilus.

Monografía en Inglés | LILACS, UY-BNMED, BNUY | ID: biblio-1293115

18.

A unique mechanism of nuclear division in Giardia lamblia involves components of the ventral disk and the nuclear envelope.

Solari, Alberto J; Rahn, Monica I; Saura, Alicia; Lujan, Hugo D.

Biocell ; 27(3): 329-46, 2003 Dec.

Artículo en Inglés | BINACIS | ID: bin-38752

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Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery.

Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation.

Cytokines, Antibodies, and Histopathological Profiles during Giardia Infection and Variant-Specific Surface Protein-Based Vaccination.

Antigenic variation in Giardia lamblia is regulated by RNA interference.

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia.

A Thermostable Oral SARS-CoV-2 Vaccine Induces Mucosal and Protective Immunity.

ORF-C4 from the early branching eukaryote Giardia lamblia displays characteristics of alpha-crystallin small heat-shock proteins.

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.

Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia.

Vaccination of domestic animals with a novel oral vaccine prevents Giardia infections, alleviates signs of giardiasis and reduces transmission to humans.

A unique mechanism of nuclear division in Giardia lamblia involves components of the ventral disk and the nuclear envelope.

Disruption of antigenic variation is crucial for effective parasite vaccine.

Dephosphorylation of cyst wall proteins by a secreted lysosomal acid phosphatase is essential for excystation of Giardia lamblia.

Identification of variant-specific surface proteins in Giardia muris trophozoites.

Nuevos métodos para el diagnóstico microbiológico de la amebiasis y de otros protozoarios intestinales / New methods for the microbiological diagnosis of amebiasis and other intestinal protozoa

Nuevos métodos para el diagnóstico microbiológico de la amebiasis y de otros protozoarios intestinales / New methods for the microbiological diagnosis of amebiasis and other intestinal protozoa

Instituciones psiquiátricas en el contexto de la pandemia por COVID-19, 2020 / Psychiatric institutions in the context of the COVID-19 pandemic, 2020

A unique mechanism of nuclear division in Giardia lamblia involves components of the ventral disk and the nuclear envelope.