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1.

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.

Lu, Qiao; Liu, Jia; Zhao, Shuai; Gomez Castro, Maria Florencia; Laurent-Rolle, Maudry; Dong, Jianbo; Ran, Xiaojuan; Damani-Yokota, Payal; Tang, Hongzhen; Karakousi, Triantafyllia; Son, Juhee; Kaczmarek, Maria E; Zhang, Ze; Yeung, Stephen T; McCune, Broc T; Chen, Rita E; Tang, Fei; Ren, Xianwen; Chen, Xufeng; Hsu, Jack C C; Teplova, Marianna; Huang, Betty; Deng, Haijing; Long, Zhilin; Mudianto, Tenny; Jin, Shumin; Lin, Peng; Du, Jasper; Zang, Ruochen; Su, Tina Tianjiao; Herrera, Alberto; Zhou, Ming; Yan, Renhong; Cui, Jia; Zhu, James; Zhou, Qiang; Wang, Tao; Ma, Jianzhu; Koralov, Sergei B; Zhang, Zemin; Aifantis, Iannis; Segal, Leopoldo N; Diamond, Michael S; Khanna, Kamal M; Stapleford, Kenneth A; Cresswell, Peter; Liu, Yue; Ding, Siyuan; Xie, Qi; Wang, Jun.

Immunity ; 54(6): 1304-1319.e9, 2021 06 08.

Artículo en Inglés | MEDLINE | ID: mdl-34048708

2.

Targeting the m⁶A RNA modification pathway blocks SARS-CoV-2 and HCoV-OC43 replication.

Burgess, Hannah M; Depledge, Daniel P; Thompson, Letitia; Srinivas, Kalanghad Puthankalam; Grande, Rebecca C; Vink, Elizabeth I; Abebe, Jonathan S; Blackaby, Wesley P; Hendrick, Alan; Albertella, Mark R; Kouzarides, Tony; Stapleford, Kenneth A; Wilson, Angus C; Mohr, Ian.

Genes Dev ; 35(13-14): 1005-1019, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-34168039

3.

Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection.

Jang, Kyung Ku; Kaczmarek, Maria E; Dallari, Simone; Chen, Ying-Han; Tada, Takuya; Axelrad, Jordan; Landau, Nathaniel R; Stapleford, Kenneth A; Cadwell, Ken.

PLoS Biol ; 20(3): e3001592, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-35358182

4.

The La Crosse virus class II fusion glycoprotein ij loop contributes to infectivity and replication in vitro and in vivo.

Thannickal, Sara A; Spector, Sophie N; Stapleford, Kenneth A.

J Virol ; 97(8): e0081923, 2023 08 31.

Artículo en Inglés | MEDLINE | ID: mdl-37578236

5.

The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication.

Li, Jie; Gui, Qi; Liang, Feng-Xia; Sall, Joseph; Zhang, Qingyue; Duan, Yatong; Dhabaria, Avantika; Askenazi, Manor; Ueberheide, Beatrix; Stapleford, Kenneth A; Pagano, Michele.

J Virol ; 97(10): e0050723, 2023 10 31.

Artículo en Inglés | MEDLINE | ID: mdl-37768083

6.

Emerging Chikungunya Virus Variants at the E1-E1 Interglycoprotein Spike Interface Impact Virus Attachment and Inflammation.

Rangel, Margarita V; McAllister, Nicole; Dancel-Manning, Kristen; Noval, Maria G; Silva, Laurie A; Stapleford, Kenneth A.

J Virol ; 96(4): e0158621, 2022 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-34935436

7.

Structurally Conserved Domains between Flavivirus and Alphavirus Fusion Glycoproteins Contribute to Replication and Infectious-Virion Production.

Rangel, Margarita V; Catanzaro, Nicholas; Thannickal, Sara A; Crotty, Kelly A; Noval, Maria G; Johnson, Katherine E E; Ghedin, Elodie; Lazear, Helen M; Stapleford, Kenneth A.

J Virol ; 96(2): e0177421, 2022 01 26.

Artículo en Inglés | MEDLINE | ID: mdl-34757841

8.

Atovaquone Inhibits Arbovirus Replication through the Depletion of Intracellular Nucleotides.

Cifuentes Kottkamp, Angelica; De Jesus, Elfie; Grande, Rebecca; Brown, Julia A; Jacobs, Adam R; Lim, Jean K; Stapleford, Kenneth A.

J Virol ; 93(11)2019 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-30894466

9.

Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are Attenuated In Vivo and Have Compromised Transmissibility.

Carrau, Lucía; Rezelj, Veronica V; Noval, María G; Levi, Laura I; Megrian, Daniela; Blanc, Herve; Weger-Lucarelli, James; Moratorio, Gonzalo; Stapleford, Kenneth A; Vignuzzi, Marco.

J Virol ; 93(18)2019 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-31270226

10.

Chikungunya Virus Overcomes Polyamine Depletion by Mutation of nsP1 and the Opal Stop Codon To Confer Enhanced Replication and Fitness.

Mounce, Bryan C; Cesaro, Teresa; Vlajnic, Lea; Vidina, Anna; Vallet, Thomas; Weger-Lucarelli, James; Passoni, Gabriella; Stapleford, Kenneth A; Levraud, Jean-Pierre; Vignuzzi, Marco.

J Virol ; 91(15)2017 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-28539441

11.

Low-Fidelity Polymerases of Alphaviruses Recombine at Higher Rates To Overproduce Defective Interfering Particles.

Poirier, Enzo Z; Mounce, Bryan C; Rozen-Gagnon, Kathryn; Hooikaas, Peter Jan; Stapleford, Kenneth A; Moratorio, Gonzalo; Vignuzzi, Marco.

J Virol ; 90(5): 2446-54, 2015 Dec 16.

Artículo en Inglés | MEDLINE | ID: mdl-26676773

12.

Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion.

Stapleford, Kenneth A; Rozen-Gagnon, Kathryn; Das, Pratyush Kumar; Saul, Sirle; Poirier, Enzo Z; Blanc, Hervé; Vidalain, Pierre-Olivier; Merits, Andres; Vignuzzi, Marco.

J Virol ; 89(22): 11233-44, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26311883

13.

Alphavirus mutator variants present host-specific defects and attenuation in mammalian and insect models.

Rozen-Gagnon, Kathryn; Stapleford, Kenneth A; Mongelli, Vanesa; Blanc, Hervé; Failloux, Anna-Bella; Saleh, Maria-Carla; Vignuzzi, Marco.

PLoS Pathog ; 10(1): e1003877, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-24453971

14.

A New Vaccine for Chikungunya Virus.

Stapleford, Kenneth A; Mulligan, Mark J.

JAMA ; 323(14): 1351-1352, 2020 04 14.

Artículo en Inglés | MEDLINE | ID: mdl-32286634

15.

La Crosse virus reassortants highlight genomic determinants of infection and pathogenesis.

Rondeau, Nicole C; Spector, Sophie N; Thannickal, Sara A; Stapleford, Kenneth A.

bioRxiv ; 2024 Mar 11.

Artículo en Inglés | MEDLINE | ID: mdl-38559198

16.

Distinct chikungunya virus polymerase palm subdomains contribute to virus replication and virion assembly.

Martin, Marie-France; Bonaventure, Boris; McCray, Nia E; Peersen, Olve B; Rozen-Gagnon, Kathryn; Stapleford, Kenneth A.

bioRxiv ; 2024 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-38293111

17.

The La Crosse virus class II fusion glycoprotein ij loop contributes to infectivity and cholesterol-dependent entry.

Thannickal, Sara A; Spector, Sophie N; Stapleford, Kenneth A.

bioRxiv ; 2023 Feb 23.

Artículo en Inglés | MEDLINE | ID: mdl-36865275

18.

The chikungunya virus E1 glycoprotein fusion loop and hinge alter glycoprotein dynamics leading to cell and host specific changes in infectivity.

Thannickal, Sara A; Battini, Leandro; Spector, Sophie N; Noval, Maria G; Álvarez, Diego E; Stapleford, Kenneth A.

bioRxiv ; 2023 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-37961096

19.

MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation.

Noval, Maria G; Spector, Sophie N; Bartnicki, Eric; Izzo, Franco; Narula, Navneet; Yeung, Stephen T; Damani-Yokota, Payal; Dewan, M Zahidunnabi; Mezzano, Valeria; Rodriguez-Rodriguez, Bruno A; Loomis, Cynthia; Khanna, Kamal M; Stapleford, Kenneth A.

Nat Commun ; 14(1): 4668, 2023 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-37537212

20.

SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels.

Eberhardt, Natalia; Noval, Maria Gabriela; Kaur, Ravneet; Amadori, Letizia; Gildea, Michael; Sajja, Swathy; Das, Dayasagar; Cilhoroz, Burak; Stewart, O'Jay; Fernandez, Dawn M; Shamailova, Roza; Guillen, Andrea Vasquez; Jangra, Sonia; Schotsaert, Michael; Newman, Jonathan D; Faries, Peter; Maldonado, Thomas; Rockman, Caron; Rapkiewicz, Amy; Stapleford, Kenneth A; Narula, Navneet; Moore, Kathryn J; Giannarelli, Chiara.

Nat Cardiovasc Res ; 2(10): 899-916, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-38076343

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