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1.
Gan To Kagaku Ryoho ; 50(13): 1390-1392, 2023 Dec.
Artículo en Japonés | MEDLINE | ID: mdl-38303284

RESUMEN

A 63-year-old female patient was diagnosed with cecal cancer(cT3, N2a, M0)and underwent surgery for the first time. Only laparoscopic ileocecal resection(D3 dissection)was performed because intraperitoneal observation revealed peritoneal metastasis around the tumor and uterus. We decided to perform a radical resection because the peritoneal metastasis was localized by FDG-PET/CT. Five courses of neoadjuvant chemotherapy(mFOLFOX6)were performed to shrink the tumor. Unrecognized peritoneal metastases were found in other areas during the second surgery. Although the extent of the peritoneal metastasis was P3, all lesions had been resected. No perioperative complications occurred, and adjuvant chemotherapy was administered to the patient. Recurrence was not observed until 6 months postoperatively.


Asunto(s)
Neoplasias del Ciego , Laparoscopía , Neoplasias Peritoneales , Femenino , Humanos , Persona de Mediana Edad , Neoplasias Peritoneales/tratamiento farmacológico , Neoplasias Peritoneales/cirugía , Neoplasias Peritoneales/secundario , Tomografía Computarizada por Tomografía de Emisión de Positrones , Terapia Neoadyuvante , Neoplasias del Ciego/tratamiento farmacológico , Neoplasias del Ciego/cirugía , Neoplasias del Ciego/patología , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico
2.
Gan To Kagaku Ryoho ; 43(9): 1101-3, 2016 Sep.
Artículo en Japonés | MEDLINE | ID: mdl-27628552

RESUMEN

A 52-year-old woman presented with redness and swelling with a peau d'orange appearance in the whole right breast. Ultrasound revealed elevated subcutaneus fat density and a diffuse hypoechoic area. She was diagnosed with inflammatory breast cancer(T4dN2M0, Stage III B of the HER2 subtype). After 4 courses of EC treatment as primary systemic therapy, the hypoechoic area was still present. Subsequent chemotherapy with pertuzumab, trastuzumab, and docetaxel was effective, as hypoechoic area was not observed on ultrasound. She underwent mastectomy and axillary dissection, and pathological examination revealed pCR. At present, 2 years after surgery, the patient is alive with no reccurence.


Asunto(s)
Anticuerpos Monoclonales Humanizados/uso terapéutico , Neoplasias Inflamatorias de la Mama/tratamiento farmacológico , Terapia Neoadyuvante , Biopsia , Femenino , Humanos , Neoplasias Inflamatorias de la Mama/química , Neoplasias Inflamatorias de la Mama/patología , Neoplasias Inflamatorias de la Mama/cirugía , Mastectomía , Persona de Mediana Edad , Estadificación de Neoplasias , Receptor ErbB-2/análisis , Receptor ErbB-2/metabolismo , Resultado del Tratamiento
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