Group A streptococcal tonsillopharyngitis burden in a tertiary Turkish hospital.

Acute tonsillopharyngitis is a very common upper respiratory tract infection and might cause serious morbidity and even mortality if not handled properly. Although the etiologic agent is mostly viral, group A beta hemolytic streptococcus is the most important bacterial agent, with a frequency of 15-30% in the pediatric age group. In this article, as the social burden for this infection is notable and almost one-third of costs are estimated to be non-medical, we applied a questionnaire to the parents of 100 proven group A tonsillopharyngitis patients to describe the social cost of this infection.

A case report of thrombocytopenia-associated multiple organ failure secondary to Salmonella enterica serotype Typhi infection in a pediatric patient: successful treatment with plasma exchange.

A high proportion of the patients with Salmonella enterica serotype Typhi infection develop severe sepsis. The mortality rate is high despite aggressive antimicrobial therapy in these patients. The case of a 10-year-old boy who developed thrombocytopenia-associated multiple organ failure (TAMOF) secondary to S. typhi infection is reported. The patient did not respond to antimicrobial treatment, including ciprofloxacin, in addition to conventional supportive measures, so plasma exchange was performed. The thrombocytopenia and organ failure had resolved after 3 days of plasma exchange therapy. Plasma exchange is suggested to be a life-saving intervention in a child with TAMOF secondary to S. typhi infection.