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1.

Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells.

Newman, Alice Clare; Falcone, Mattia; Huerta Uribe, Alejandro; Zhang, Tong; Athineos, Dimitris; Pietzke, Matthias; Vazquez, Alexei; Blyth, Karen; Maddocks, Oliver David Kenneth.

Mol Cell ; 81(11): 2290-2302.e7, 2021 06 03.

Artículo en Inglés | MEDLINE | ID: mdl-33831358

2.

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.

Burgos-Barragan, Guillermo; Wit, Niek; Meiser, Johannes; Dingler, Felix A; Pietzke, Matthias; Mulderrig, Lee; Pontel, Lucas B; Rosado, Ivan V; Brewer, Thomas F; Cordell, Rebecca L; Monks, Paul S; Chang, Christopher J; Vazquez, Alexei; Patel, Ketan J.

Nature ; 548(7669): 549-554, 2017 08 31.

Artículo en Inglés | MEDLINE | ID: mdl-28813411

3.

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.

Burgos-Barragan, Guillermo; Wit, Niek; Meiser, Johannes; Dingler, Felix A; Pietzke, Matthias; Mulderrig, Lee; Pontel, Lucas B; Rosado, Ivan V; Brewer, Thomas F; Cordell, Rebecca L; Monks, Paul S; Chang, Christopher J; Vazquez, Alexei; Patel, Ketan J.

Nature ; 548(7669): 612, 2017 08 31.

Artículo en Inglés | MEDLINE | ID: mdl-29411778

4.

Robustness and Complexity of Directed and Weighted Metabolic Hypergraphs.

Traversa, Pietro; Ferraz de Arruda, Guilherme; Vazquez, Alexei; Moreno, Yamir.

Entropy (Basel) ; 25(11)2023 Nov 11.

Artículo en Inglés | MEDLINE | ID: mdl-37998229

5.

Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer.

Halim, Silvia; Markert, Elke K; Vazquez, Alexei.

Br J Cancer ; 119(7): 855-863, 2018 10.

Artículo en Inglés | MEDLINE | ID: mdl-30287917

6.

Cancer metabolism at a glance.

Vazquez, Alexei; Kamphorst, Jurre J; Markert, Elke K; Schug, Zachary T; Tardito, Saverio; Gottlieb, Eyal.

J Cell Sci ; 129(18): 3367-73, 2016 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-27635066

7.

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.

Hirshfield, Kim M; Tolkunov, Denis; Zhong, Hua; Ali, Siraj M; Stein, Mark N; Murphy, Susan; Vig, Hetal; Vazquez, Alexei; Glod, John; Moss, Rebecca A; Belyi, Vladimir; Chan, Chang S; Chen, Suzie; Goodell, Lauri; Foran, David; Yelensky, Roman; Palma, Norma A; Sun, James X; Miller, Vincent A; Stephens, Philip J; Ross, Jeffrey S; Kaufman, Howard; Poplin, Elizabeth; Mehnert, Janice; Tan, Antoinette R; Bertino, Joseph R; Aisner, Joseph; DiPaola, Robert S; Rodriguez-Rodriguez, Lorna; Ganesan, Shridar.

Oncologist ; 21(11): 1315-1325, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27566247

8.

Small molecule compounds targeting the p53 pathway: are we finally making progress?

Yu, Xin; Narayanan, Sumana; Vazquez, Alexei; Carpizo, Darren R.

Apoptosis ; 19(7): 1055-68, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24756955

9.

Molecular classification of prostate cancer using curated expression signatures.

Markert, Elke K; Mizuno, Hideaki; Vazquez, Alexei; Levine, Arnold J.

Proc Natl Acad Sci U S A ; 108(52): 21276-81, 2011 Dec 27.

Artículo en Inglés | MEDLINE | ID: mdl-22123976

10.

Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing.

Zarou, Martha M; Rattigan, Kevin M; Sarnello, Daniele; Shokry, Engy; Dawson, Amy; Ianniciello, Angela; Dunn, Karen; Copland, Mhairi; Sumpton, David; Vazquez, Alexei; Helgason, G Vignir.

Nat Commun ; 15(1): 1931, 2024 Mar 02.

Artículo en Inglés | MEDLINE | ID: mdl-38431691

11.

Inference of synergy/antagonism between anticancer drugs from the pooled analysis of clinical trials.

Kang, Wenfeng; DiPaola, Robert S; Vazquez, Alexei.

BMC Med Res Methodol ; 13: 77, 2013 Jun 12.

Artículo en Inglés | MEDLINE | ID: mdl-23758906

12.

Complex hypergraphs.

Vazquez, Alexei.

Phys Rev E ; 107(2-1): 024316, 2023 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-36932522

13.

Activity networks determine project performance.

Vazquez, Alexei; Pozzana, Iacopo; Kalogridis, Georgios; Ellinas, Christos.

Sci Rep ; 13(1): 509, 2023 01 10.

Artículo en Inglés | MEDLINE | ID: mdl-36627400

14.

HEK293 producing the extracellular domain HER1: Full datasets of continuous fermentation process and metabolites analysis.

Calzadilla, Lisandra; Hernández, Erick; Dustet, Julio; Fernandez-de-Cossio-Diaz, Jorge; León, Kalet; Pietzke, Matthias; Vazquez, Alexei; Mulet, Roberto; Boggiano, Tammy.

Data Brief ; 50: 109604, 2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-37808545

15.

An empirical framework for binary interactome mapping.

Venkatesan, Kavitha; Rual, Jean-François; Vazquez, Alexei; Stelzl, Ulrich; Lemmens, Irma; Hirozane-Kishikawa, Tomoko; Hao, Tong; Zenkner, Martina; Xin, Xiaofeng; Goh, Kwang-Il; Yildirim, Muhammed A; Simonis, Nicolas; Heinzmann, Kathrin; Gebreab, Fana; Sahalie, Julie M; Cevik, Sebiha; Simon, Christophe; de Smet, Anne-Sophie; Dann, Elizabeth; Smolyar, Alex; Vinayagam, Arunachalam; Yu, Haiyuan; Szeto, David; Borick, Heather; Dricot, Amélie; Klitgord, Niels; Murray, Ryan R; Lin, Chenwei; Lalowski, Maciej; Timm, Jan; Rau, Kirstin; Boone, Charles; Braun, Pascal; Cusick, Michael E; Roth, Frederick P; Hill, David E; Tavernier, Jan; Wanker, Erich E; Barabási, Albert-László; Vidal, Marc.

Nat Methods ; 6(1): 83-90, 2009 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-19060904

16.

Tropical approximation to finish time of activity networks.

Vazquez, Alexei.

Phys Rev E ; 106(1): L012301, 2022 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-35974504

17.

Erratum: Tropical approximation to finish time of activity networks [Phys. Rev. E 106, L012301 (2022)].

Vazquez, Alexei.

Phys Rev E ; 106(6-2): 069901, 2022 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-36671200

18.

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis.

Kiweler, Nicole; Delbrouck, Catherine; Pozdeev, Vitaly I; Neises, Laura; Soriano-Baguet, Leticia; Eiden, Kim; Xian, Feng; Benzarti, Mohaned; Haase, Lara; Koncina, Eric; Schmoetten, Maryse; Jaeger, Christian; Noman, Muhammad Zaeem; Vazquez, Alexei; Janji, Bassam; Dittmar, Gunnar; Brenner, Dirk; Letellier, Elisabeth; Meiser, Johannes.

Nat Commun ; 13(1): 2699, 2022 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-35577770

19.

A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence.

Vazquez, Alexei; Kulkarni, Diptee; Grochola, Lukasz F; Bond, Gareth L; Barnard, Nicola; Toppmeyer, Deborah; Levine, Arnold J; Hirshfield, Kim M.

Int J Cancer ; 128(10): 2335-43, 2011 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-20669227

20.

Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes.

Mehta, Madhura S; Vazquez, Alexei; Kulkarni, Diptee A; Kerrigan, John E; Atwal, Gurinder; Metsugi, Shoichi; Toppmeyer, Deborah L; Levine, Arnold J; Hirshfield, Kim M.

Breast Cancer Res Treat ; 125(3): 861-8, 2011 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-20658316

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Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells.

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.

Robustness and Complexity of Directed and Weighted Metabolic Hypergraphs.

Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer.

Cancer metabolism at a glance.

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.

Small molecule compounds targeting the p53 pathway: are we finally making progress?

Molecular classification of prostate cancer using curated expression signatures.

Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing.

Inference of synergy/antagonism between anticancer drugs from the pooled analysis of clinical trials.

Complex hypergraphs.

Activity networks determine project performance.

HEK293 producing the extracellular domain HER1: Full datasets of continuous fermentation process and metabolites analysis.

An empirical framework for binary interactome mapping.

Tropical approximation to finish time of activity networks.

Erratum: Tropical approximation to finish time of activity networks [Phys. Rev. E 106, L012301 (2022)].

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis.

A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence.

Polymorphic variants in TSC1 and TSC2 and their association with breast cancer phenotypes.