RESUMEN
These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group of European experts following a systematic review of the current literature, an expert conference held in Toulouse in 2016, and a consensus on the discussions. These guidelines summarize evidence and expert-based recommendations and intend to help clinicians with the management of these rare and often complex diseases. These guidelines comprise two sections. This is part two, covering the management of complications and the particularities of some forms of congenital ichthyosis.
Asunto(s)
Consenso , Dermatología/normas , Eritrodermia Ictiosiforme Congénita/terapia , Ictiosis/terapia , Enfermedades del Prematuro/terapia , Dermatología/métodos , Europa (Continente) , Humanos , Eritrodermia Ictiosiforme Congénita/complicaciones , Ictiosis/complicacionesRESUMEN
These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group of European experts following a systematic review of the current literature, an expert conference held in Toulouse in 2016 and a consensus on the discussions. They summarize evidence and expert-based recommendations and are intended to help clinicians with the management of these rare and often complex diseases. These guidelines comprise two sections. This is part one, covering topical therapies, systemic therapies, psychosocial management, communicating the diagnosis and genetic counselling.
Asunto(s)
Terapia Conductista/normas , Consenso , Fármacos Dermatológicos/uso terapéutico , Dermatología/normas , Eritrodermia Ictiosiforme Congénita/terapia , Administración Oral , Administración Tópica , Terapia Conductista/métodos , Dermatología/métodos , Europa (Continente) , Asesoramiento Genético/normas , Humanos , Eritrodermia Ictiosiforme Congénita/diagnóstico , Eritrodermia Ictiosiforme Congénita/psicología , Calidad de Vida , Apoyo Social , Revisiones Sistemáticas como AsuntoRESUMEN
BACKGROUND: Knowledge about frailty among patients seen by general practitioners (GP) is currently limited. PATIENTS AND METHODS: Frailty assessment by the criteria of Fried and additional documentation was performed at a GP's office. RESULTS: Out of 119 participating patients, 14.3% were classified as frail, 52.1% as prefrail, and 33.6% as not frail. Frailty was associated with comorbidity, the number of drugs prescribed, depressive symptoms, cognitive function, and frequency of falls. CONCLUSION: The prevalence of frailty is high among the cohort of elderly persons seen by a GP. Routine frailty assessment will help to direct preventive and therapeutic interventions.
Asunto(s)
Médicos Generales/estadística & datos numéricos , Evaluación Geriátrica/estadística & datos numéricos , Debilidad Muscular/diagnóstico , Debilidad Muscular/epidemiología , Pautas de la Práctica en Medicina/estadística & datos numéricos , Anciano , Anciano de 80 o más Años , Femenino , Alemania/epidemiología , Humanos , Masculino , Proyectos Piloto , Prevalencia , SíndromeAsunto(s)
Enfermedad Coronaria/cirugía , Anomalías de los Vasos Coronarios/cirugía , Atrios Cardíacos/anomalías , Angiografía Coronaria , Enfermedad Coronaria/diagnóstico por imagen , Anomalías de los Vasos Coronarios/diagnóstico por imagen , Atrios Cardíacos/diagnóstico por imagen , Atrios Cardíacos/cirugía , Humanos , Masculino , Persona de Mediana Edad , Técnicas de SuturaRESUMEN
One month after a successful angioplasty, one of our patients developed a new aneurysm in the right coronary artery (RCA). The aneurysm was characterized as a pseudoaneurysm by the use of intravascular ultrasound (IVUS). A stenosis that was not well seen by angiography was better depicted by IVUS. Both the pseudoaneurysm and the stenosis were successfully treated with a second angioplasty and stenting with a covered stent. Delayed development of pseudoaneurysms after dissection is an uncommon, but possible complication after angioplasty. In this case IVUS was useful for accurate characterization of the aneurysm. The use of covered stents may become a clinically useful method for treating coronary pseudoaneurysms.
Asunto(s)
Aneurisma Falso/etiología , Angioplastia Coronaria con Balón/efectos adversos , Aneurisma Coronario/etiología , Anciano , Aneurisma Falso/diagnóstico por imagen , Aneurisma Coronario/diagnóstico por imagen , Angiografía Coronaria , Humanos , Masculino , Stents , Factores de Tiempo , Ultrasonografía IntervencionalRESUMEN
1. The gonadospecific DIA3 types were traceable for 4 weeks, in some cases for 6 weeks. 2. EsD polymorphism was not demonstrable by starch gel electrophoresis in sperm, not even in sperm lysates. 3. EsA patterns showed only non-reproducible differences. 4. Because of their low concentrations, salivary esterase cannot cause errors when mixed stains are examined.