1.
J Org Chem
; 87(16): 10890-10901, 2022 Aug 19.
Artículo
en Inglés
| MEDLINE
| ID: mdl-35918174
RESUMEN
MgI2-catalyzed nucleophilic ring-opening reactions of donor-acceptor cyclopropanes with indoline-2-thiones as easy-to-handle sulfur nucleophiles were investigated. A series of functionalized γ-indolylthio butyric acid derivatives were synthesized in good to excellent yields under mild reaction conditions. Furthermore, the thioether functionalized ring-opening products could be transformed to sulfone and methionine analogues.