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1.

A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.

Kreye, Jakob; Reincke, S Momsen; Kornau, Hans-Christian; Sánchez-Sendin, Elisa; Corman, Victor Max; Liu, Hejun; Yuan, Meng; Wu, Nicholas C; Zhu, Xueyong; Lee, Chang-Chun D; Trimpert, Jakob; Höltje, Markus; Dietert, Kristina; Stöffler, Laura; von Wardenburg, Niels; van Hoof, Scott; Homeyer, Marie A; Hoffmann, Julius; Abdelgawad, Azza; Gruber, Achim D; Bertzbach, Luca D; Vladimirova, Daria; Li, Lucie Y; Barthel, Paula Charlotte; Skriner, Karl; Hocke, Andreas C; Hippenstiel, Stefan; Witzenrath, Martin; Suttorp, Norbert; Kurth, Florian; Franke, Christiana; Endres, Matthias; Schmitz, Dietmar; Jeworowski, Lara Maria; Richter, Anja; Schmidt, Marie Luisa; Schwarz, Tatjana; Müller, Marcel Alexander; Drosten, Christian; Wendisch, Daniel; Sander, Leif E; Osterrieder, Nikolaus; Wilson, Ian A; Prüss, Harald.

Cell ; 183(4): 1058-1069.e19, 2020 11 12.

Artículo en Inglés | MEDLINE | ID: mdl-33058755

2.

Deception through Mimicry: A Cellular Antiviral Strategy.

Wu, Nicholas C; Ward, Andrew B.

Cell ; 175(7): 1728-1729, 2018 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-30550784

3.

Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.

Lei, Ruipeng; Kim, Wooseob; Lv, Huibin; Mou, Zongjun; Scherm, Michael J; Schmitz, Aaron J; Turner, Jackson S; Tan, Timothy J C; Wang, Yiquan; Ouyang, Wenhao O; Liang, Weiwen; Rivera-Cardona, Joel; Teo, Chuyun; Graham, Claire S; Brooke, Christopher B; Presti, Rachel M; Mok, Chris K P; Krammer, Florian; Dai, Xinghong; Ellebedy, Ali H; Wu, Nicholas C.

Immunity ; 56(11): 2621-2634.e6, 2023 Nov 14.

Artículo en Inglés | MEDLINE | ID: mdl-37967533

4.

A large-scale systematic survey reveals recurring molecular features of public antibody responses to SARS-CoV-2.

Wang, Yiquan; Yuan, Meng; Lv, Huibin; Peng, Jian; Wilson, Ian A; Wu, Nicholas C.

Immunity ; 55(6): 1105-1117.e4, 2022 06 14.

Artículo en Inglés | MEDLINE | ID: mdl-35397794

5.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

York, Autumn G; Williams, Kevin J; Argus, Joseph P; Zhou, Quan D; Brar, Gurpreet; Vergnes, Laurent; Gray, Elizabeth E; Zhen, Anjie; Wu, Nicholas C; Yamada, Douglas H; Cunningham, Cameron R; Tarling, Elizabeth J; Wilks, Moses Q; Casero, David; Gray, David H; Yu, Amy K; Wang, Eric S; Brooks, David G; Sun, Ren; Kitchen, Scott G; Wu, Ting-Ting; Reue, Karen; Stetson, Daniel B; Bensinger, Steven J.

Cell ; 163(7): 1716-29, 2015 Dec 17.

Artículo en Inglés | MEDLINE | ID: mdl-26686653

6.

Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.

Liu, Hejun; Wu, Nicholas C; Yuan, Meng; Bangaru, Sandhya; Torres, Jonathan L; Caniels, Tom G; van Schooten, Jelle; Zhu, Xueyong; Lee, Chang-Chun D; Brouwer, Philip J M; van Gils, Marit J; Sanders, Rogier W; Ward, Andrew B; Wilson, Ian A.

Immunity ; 53(6): 1272-1280.e5, 2020 12 15.

Artículo en Inglés | MEDLINE | ID: mdl-33242394

7.

Targeting neuraminidase: the next frontier for broadly protective influenza vaccines.

Wu, Nicholas C; Ellebedy, Ali H.

Trends Immunol ; 45(1): 11-19, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-38103991

8.

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike.

Tan, Timothy J C; Verma, Abhishek K; Odle, Abby; Lei, Ruipeng; Meyerholz, David K; Matreyek, Kenneth A; Perlman, Stanley; Wong, Lok-Yin Roy; Wu, Nicholas C.

Proc Natl Acad Sci U S A ; 121(15): e2317222121, 2024 Apr 09.

Artículo en Inglés | MEDLINE | ID: mdl-38557175

9.

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic ß-Hairpin Structure.

Lee, Jeong Hyun; Andrabi, Raiees; Su, Ching-Yao; Yasmeen, Anila; Julien, Jean-Philippe; Kong, Leopold; Wu, Nicholas C; McBride, Ryan; Sok, Devin; Pauthner, Matthias; Cottrell, Christopher A; Nieusma, Travis; Blattner, Claudia; Paulson, James C; Klasse, Per Johan; Wilson, Ian A; Burton, Dennis R; Ward, Andrew B.

Immunity ; 46(4): 690-702, 2017 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-28423342

10.

Defining and Studying B Cell Receptor and TCR Interactions.

Rappazzo, C Garrett; Fernández-Quintero, Monica L; Mayer, Andreas; Wu, Nicholas C; Greiff, Victor; Guthmiller, Jenna J.

J Immunol ; 211(3): 311-322, 2023 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-37459189

11.

A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2.

Yin, Qian; Luo, Wei; Mallajosyula, Vamsee; Bo, Yang; Guo, Jing; Xie, Jinghang; Sun, Meng; Verma, Rohit; Li, Chunfeng; Constantz, Christian M; Wagar, Lisa E; Li, Jing; Sola, Elsa; Gupta, Neha; Wang, Chunlin; Kask, Oliver; Chen, Xin; Yuan, Xue; Wu, Nicholas C; Rao, Jianghong; Chien, Yueh-Hsiu; Cheng, Jianjun; Pulendran, Bali; Davis, Mark M.

Nat Mater ; 22(3): 380-390, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36717665

12.

Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution.

Liang, Weiwen; Tan, Timothy J C; Wang, Yiquan; Lv, Huibin; Sun, Yuanxin; Bruzzone, Roberto; Mok, Chris K P; Wu, Nicholas C.

PLoS Pathog ; 18(9): e1010875, 2022 09.

Artículo en Inglés | MEDLINE | ID: mdl-36155668

13.

Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression.

Diefenbacher, Meghan; Tan, Timothy J C; Bauer, David L V; Stadtmueller, Beth M; Wu, Nicholas C; Brooke, Christopher B.

J Virol ; 96(10): e0020522, 2022 05 25.

Artículo en Inglés | MEDLINE | ID: mdl-35467364

14.

A cross-neutralizing antibody between HIV-1 and influenza virus.

Lee, Chang-Chun D; Watanabe, Yasunori; Wu, Nicholas C; Han, Julianna; Kumar, Sonu; Pholcharee, Tossapol; Seabright, Gemma E; Allen, Joel D; Lin, Chih-Wei; Yang, Ji-Rong; Liu, Ming-Tsan; Wu, Chung-Yi; Ward, Andrew B; Crispin, Max; Wilson, Ian A.

PLoS Pathog ; 17(3): e1009407, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-33750987

15.

Sublethal consequences of ultraviolet radiation exposure on vertebrates: Synthesis through meta-analysis.

Downie, Adam T; Wu, Nicholas C; Cramp, Rebecca L; Franklin, Craig E.

Glob Chang Biol ; 29(23): 6620-6634, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-37366045

16.

Immunity against cancer cells may promote their proliferation and metastasis.

Lin, Chih-Wei; Xie, Jia; Zhang, Ding; Han, Kyung Ho; Grande, Geramie; Wu, Nicholas C; Yang, Zhuo; Yea, Kyungmoo; Lerner, Richard A.

Proc Natl Acad Sci U S A ; 117(1): 426-431, 2020 01 07.

Artículo en Inglés | MEDLINE | ID: mdl-31871166

17.

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.

Yao, Yao; Kadam, Rameshwar U; Lee, Chang-Chun David; Woehl, Jordan L; Wu, Nicholas C; Zhu, Xueyong; Kitamura, Seiya; Wilson, Ian A; Wolan, Dennis W.

Proc Natl Acad Sci U S A ; 117(31): 18431-18438, 2020 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-32690700

18.

Homologous and heterologous serological response to the N-terminal domain of SARS-CoV-2 in humans and mice.

Lv, Huibin; Tsang, Owen Tak-Yin; So, Ray T Y; Wang, Yiquan; Yuan, Meng; Liu, Hejun; Yip, Garrick K; Teo, Qi Wen; Lin, Yihan; Liang, Weiwen; Wang, Jinlin; Ng, Wilson W; Wilson, Ian A; Peiris, J S Malik; Wu, Nicholas C; Mok, Chris K P.

Eur J Immunol ; 51(9): 2296-2305, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34089541

19.

Endocrine disruption from plastic pollution and warming interact to increase the energetic cost of growth in a fish.

Wu, Nicholas C; Rubin, Alexander M; Seebacher, Frank.

Proc Biol Sci ; 289(1967): 20212077, 2022 01 26.

Artículo en Inglés | MEDLINE | ID: mdl-35078359

20.

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.

Wu, Nicholas C; Yuan, Meng; Bangaru, Sandhya; Huang, Deli; Zhu, Xueyong; Lee, Chang-Chun D; Turner, Hannah L; Peng, Linghang; Yang, Linlin; Burton, Dennis R; Nemazee, David; Ward, Andrew B; Wilson, Ian A.

PLoS Pathog ; 16(12): e1009089, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33275640

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