1.
J Org Chem
; 89(12): 8878-8887, 2024 Jun 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38845522
RESUMEN
A one-pot approach has been developed for the synthesis of α-ketothioamide derivatives from sulfur ylides, nitrosobenzenes, and thioacetic acid. This protocol is carried out under mild reaction conditions in generally moderate to excellent yields without any precious catalysts, affording the derivatives with structural diversity. Additionally, a possible mechanism for this chemical transformation is proposed.