RESUMEN
We compared the contents of collagen, glycosaminoglycans, and various forms of water in the surface layer and whole tissue of joint cartilages of different localization. It was found that the surface layer is characterized by reduced content of glycosaminoglycans compared to the whole tissue and higher water-holding capacity due high content of bound water.
Asunto(s)
Cartílago Articular/metabolismo , Articulaciones/metabolismo , Agua/metabolismo , Cartílago Articular/química , Colágeno/análisis , Glicosaminoglicanos/análisis , Humanos , Articulaciones/anatomía & histología , Articulaciones/químicaRESUMEN
Rearrangement of intra- and intermolecular bonds in collagen molecule, disaggregation of proteoglycans and their elimination from cartilage involved in osteoarthrosis are responsible for water accumulation and its increased mobility in cartilage.
Asunto(s)
Cartílago Articular/metabolismo , Cartílago/metabolismo , Osteoartritis/metabolismo , Agua/química , Cromatografía en Gel , Colágeno/metabolismo , Fémur/metabolismo , Guanidina/farmacología , Humanos , Hidrolasas/metabolismo , Proteoglicanos/metabolismo , Espectrometría de Fluorescencia , Ácidos Urónicos/farmacología , Agua/metabolismoRESUMEN
We revealed a relationship between water balance and LPO in the myocardium, liver, and blood plasma during massive blood loss and irradiation with He-Ne laser. Low-intensity laser irradiation of the plasma inhibits LPO and normalizes water balance in rat tissues during massive blood loss.