RESUMEN
Divergent synthetic methods for transforming isatins to 2-cyanoaryl carbamate and 2-cyanoaryl urea derivatives were developed using ammonium carbamate as the nitrogen source and iodobenzene diacetate as the oxidant. This reaction features mild conditions, broad substrate scope, and moreover, the use of toxic cyano-containing compounds is avoided.
Asunto(s)
Yodo , Carbamatos , Yoduros , Yodo/química , Oxidación-Reducción , UreaRESUMEN
An efficient B(C6F5)3-catalyzed aerobic oxidative C-S cross-coupling reaction of thiophenol with indoles was developed, affording a wide range of diaryl sulfides in good yields. An electron donor-acceptor complex between B(C6F5)3 and indoles was formed, facilitating the photoinduced single-electron transfer (SET) from indole substrates to the B(C6F5)3 catalyst. This protocol demonstrates a new reaction model using B(C6F5)3 as a single-electron oxidant.