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1.
Scand J Caring Sci ; 27(1): 117-22, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22671304

RESUMO

The aim of the study was to evaluate the impact of food incentives on adherence to tuberculosis (TB) drug treatment among homeless patients with TB. Food packages were thus given as a part of directly observed therapy to 142 homeless patients with TB at a dispensary in Saint Petersburg, Russian Federation. In addition, a social worker provided the patients with information and legal assistance, for example help with internal passports. Among the 142 patients, 66 were included in the study at the dispensary during their entire treatment period, while 76 patients were included in the study during shorter periods mainly because of transfer to inpatient care. In the first group, 59% of the patients continued the TB drug treatment without interruption in contrast to 31% in a control group. In the second group, that is those studied during shorter periods, 95% continued the TB drug treatment without interruption while attached to the dispensary. Food was introduced in the TB programme of the City of St. Petersburg as a consequence of this study. In conclusion, it can be stated that the food incentive had a strong positive impact on the adherence to TB drug treatment among these socially marginalized patients. The social support contributed in all probability also to the positive results.


Assuntos
Antituberculosos/uso terapêutico , Alimentos , Pessoas Mal Alojadas , Motivação , Cooperação do Paciente , Adulto , Idoso , Antituberculosos/administração & dosagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Federação Russa , Adulto Jovem
2.
Scand J Infect Dis ; 44(1): 51-4, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21736509

RESUMO

In 2009 we described an outbreak caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in southern Sweden that occurred during 2005-2006. An important finding from the investigation was the long carriage times of the ESBL-producing E. coli in several of the patients, which in some cases exceeded 30 months. Here we report findings from the continued follow-up of bacterial carriage. In September 2010, 5 of the 42 patients still carried the bacteria after a median of 58 months (range 41-59 months), 18 had had repeatedly negative cultures after shedding bacteria for a median of 7.5 months (range 0-39 months), 16 had died while still shedding the bacteria for a median of 9 months (range 0-38 months), and 3 had been lost to follow-up.


Assuntos
Portador Sadio/epidemiologia , Infecções por Escherichia coli/epidemiologia , Escherichia coli/isolamento & purificação , beta-Lactamases , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Derrame de Bactérias , Criança , Surtos de Doenças , Escherichia coli/enzimologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Suécia/epidemiologia
3.
Scand J Infect Dis ; 41(6-7): 410-5, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19396721

RESUMO

An outbreak caused by a multiresistant Escherichia coli producing CTX-M-15 ESBL occurred during autumn 2005 and spring 2006 in Kristianstad, a town in southern Sweden. The outbreak comprised 27 cases and was related to an infectious diseases ward and a neighbouring long-term care facility. Our primary objective was to investigate the epidemiology in order to control the outbreak. In addition, we studied the time of carriage of multiresistant ESBL-producing Escherichia coli by follow-up samples and measured the frequency of carriage of ESBL-producing bacteria in the patient population admitted to the infectious diseases ward during autumn 2006. The outbreak described is one of the first caused by ESBL-producing Escherichia coli in Sweden. The source of the outbreak was not found. Infection control measures were reinforced in the outbreak situation, and epidemiological and microbiological methods, including PFGE typing, were used for analysis. The carriage time of multiresistant Escherichia coli was longer in several of the affected patients than has previously been reported. The longest carriage time to date is 33 months. This demonstrates the risk for new outbreaks unless strict infection control measures are implemented. Among the patients admitted to the ward during autumn 2006, 2.5% carried ESBL-producing enterobacteria.


Assuntos
Surtos de Doenças , Infecções por Escherichia coli/epidemiologia , Escherichia coli/enzimologia , beta-Lactamases/biossíntese , Idoso , Farmacorresistência Bacteriana Múltipla , Microbiologia Ambiental , Escherichia coli/efeitos dos fármacos , Escherichia coli/genética , Escherichia coli/isolamento & purificação , Infecções por Escherichia coli/microbiologia , Feminino , Humanos , Masculino , Testes de Sensibilidade Microbiana , Suécia/epidemiologia , beta-Lactamases/genética , beta-Lactamases/metabolismo
5.
Int J Food Microbiol ; 97(2): 179-86, 2004 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-15541804

RESUMO

Following an acute foodborne gastroenteritis outbreak in southern Sweden, stool specimens from five of nine ill patients were found positive for norovirus using reverse transcriptase polymerase chain reaction. Epidemiological data pointed to raspberry cakes as the source of the outbreak. Using a combination of generic and patient-specific primers and novel food analysis methodology (with extraction efficiency control and inhibitor removal), norovirus strains from two different genogroups were directly identified in the contaminated raspberries.


Assuntos
Infecções por Caliciviridae/epidemiologia , Frutas/virologia , Gastroenterite/epidemiologia , Norovirus/isolamento & purificação , Reação em Cadeia da Polimerase Via Transcriptase Reversa/métodos , Infecções por Caliciviridae/virologia , Surtos de Doenças , Fezes/virologia , Contaminação de Alimentos/análise , Microbiologia de Alimentos , Gastroenterite/virologia , Humanos , Suécia/epidemiologia
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