Pesquisa | Portal de Pesquisa da BVS

1.

Salmonella manipulates the host to drive pathogenicity via induction of interleukin 1ß.

Zigdon, Mor; Sawaed, Jasmin; Zelik, Lilach; Binyamin, Dana; Ben-Simon, Shira; Asulin, Nofar; Levin, Rachel; Modilevsky, Sonia; Naama, Maria; Telpaz, Shahar; Rubin, Elad; Awad, Aya; Sawaed, Wisal; Harshuk-Shabso, Sarina; Nuriel-Ohayon, Meital; Krishnamohan, Mathumathi; Werbner, Michal; Koren, Omry; Winter, Sebastian E; Apte, Ron N; Voronov, Elena; Bel, Shai.

PLoS Biol ; 22(1): e3002486, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38236896

2.

One hits (almost) all.

Boraschi, Diana; Apte, Ron N; Martin, Michael U.

Nat Immunol ; 20(9): 1095-1097, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31427774

3.

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

Ludin, Aya; Itkin, Tomer; Gur-Cohen, Shiri; Mildner, Alexander; Shezen, Elias; Golan, Karin; Kollet, Orit; Kalinkovich, Alexander; Porat, Ziv; D'Uva, Gabriele; Schajnovitz, Amir; Voronov, Elena; Brenner, David A; Apte, Ron N; Jung, Steffen; Lapidot, Tsvee.

Nat Immunol ; 13(11): 1072-82, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22983360

4.

Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment.

Krishnamohan, Mathumathi; Kaplanov, Irena; Maudi-Boker, Sapir; Yousef, Muhammad; Machluf-Katz, Noy; Cohen, Idan; Elkabets, Moshe; Titus, Jaison; Bersudsky, Marina; Apte, Ron N; Voronov, Elena; Braiman, Alex.

Int J Mol Sci ; 25(7)2024 Apr 02.

Artigo em Inglês | MEDLINE | ID: mdl-38612760

5.

Pathogenetic role and clinical significance of interleukin-1ß in cancer.

Malkova, Anna M; Gubal, Anna R; Petrova, Anastasia L; Voronov, Elena; Apte, Ron N; Semenov, Konstantin N; Sharoyko, Vladimir V.

Immunology ; 168(2): 203-216, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-35462425

6.

Gene deletion of Interleukin-1α reduces ER stress-induced CHOP expression in macrophages and attenuates the progression of atherosclerosis in apoE-deficient mice.

Almog, Tal; Keshet, Rom; Kandel-Kfir, Michal; Shaish, Aviv; Apte, Ron N; Harats, Dror; Kamari, Yehuda.

Cytokine ; 167: 156212, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37146542

7.

Blocking IL-1ß reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.

Kaplanov, Irena; Carmi, Yaron; Kornetsky, Rachel; Shemesh, Avishai; Shurin, Galina V; Shurin, Michael R; Dinarello, Charles A; Voronov, Elena; Apte, Ron N.

Proc Natl Acad Sci U S A ; 116(4): 1361-1369, 2019 01 22.

Artigo em Inglês | MEDLINE | ID: mdl-30545915

8.

Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction.

Razin, Talya; Melamed-Book, Naomi; Argaman, Jasmin; Galin, Iris; Lowy, Yosef; Anuka, Eli; Naftali-Shani, Nili; Kandel-Kfir, Michal; Garfinkel, Benjamin P; Brielle, Shlomi; Granot, Zvi; Apte, Ron N; Conway, Simon J; Molkentin, Jeffery D; Kamari, Yehuda; Leor, Jonathan; Orly, Joseph.

J Mol Cell Cardiol ; 155: 125-137, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33130150

9.

Alarmins: Feel the Stress.

Rider, Peleg; Voronov, Elena; Dinarello, Charles A; Apte, Ron N; Cohen, Idan.

J Immunol ; 198(4): 1395-1402, 2017 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-28167650

10.

MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study.

Hickish, Tamas; Andre, Thierry; Wyrwicz, Lucjan; Saunders, Mark; Sarosiek, Tomasz; Kocsis, Judit; Nemecek, Radim; Rogowski, Wojciech; Lesniewski-Kmak, Krzysztof; Petruzelka, Lubos; Apte, Ron N; Mohanty, Prasant; Stecher, Michael; Simard, John; de Gramont, Aimery.

Lancet Oncol ; 18(2): 192-201, 2017 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-28094194

11.

Interleukin-1α as an intracellular alarmin in cancer biology.

Voronov, Elena; Dinarello, Charles A; Apte, Ron N.

Semin Immunol ; 38: 3-14, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-30554608

12.

Interleukin-1α.

Rider, Peleg; Carmi, Yaron; Voronov, Elena; Apte, Ron N.

Semin Immunol ; 25(6): 430-8, 2013 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-24183701

13.

Critical role for IL-1ß in DNA damage-induced mucositis.

Kanarek, Naama; Grivennikov, Sergei I; Leshets, Michael; Lasry, Audrey; Alkalay, Irit; Horwitz, Elad; Shaul, Yoav D; Stachler, Matthew; Voronov, Elena; Apte, Ron N; Pagano, Michele; Pikarsky, Eli; Karin, Michael; Ghosh, Sankar; Ben-Neriah, Yinon.

Proc Natl Acad Sci U S A ; 111(6): E702-11, 2014 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-24469832

14.

Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.

Fejer, György; Wegner, Mareike Dorothee; Györy, Ildiko; Cohen, Idan; Engelhard, Peggy; Voronov, Elena; Manke, Thomas; Ruzsics, Zsolt; Dölken, Lars; Prazeres da Costa, Olivia; Branzk, Nora; Huber, Michael; Prasse, Antje; Schneider, Robert; Apte, Ron N; Galanos, Chris; Freudenberg, Marina A.

Proc Natl Acad Sci U S A ; 110(24): E2191-8, 2013 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-23708119

15.

Multifunctional activity of a small tellurium redox immunomodulator compound, AS101, on dextran sodium sulfate-induced murine colitis.

Halpert, Gilad; Eitan, Tom; Voronov, Elena; Apte, Ron N; Rath-Wolfson, Lea; Albeck, Michael; Kalechman, Yona; Sredni, Benjamin.

J Biol Chem ; 289(24): 17215-27, 2014 Jun 13.

Artigo em Inglês | MEDLINE | ID: mdl-24764299

16.

Involvement of IL-1 genes in the cellular responses to carbon nanotube exposure.

Arnoldussen, Yke Jildouw; Skogstad, Asbjørn; Skaug, Vidar; Kasem, Mayes; Haugen, Aage; Benker, Nathalie; Weinbruch, Stephan; Apte, Ron N; Zienolddiny, Shanbeh.

Cytokine ; 73(1): 128-37, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25748835

17.

Knockdown of interleukin-1α does not attenuate LPS-induced production of interleukin-1ß in mouse macrophages.

Almog, Tal; Kandel-Kfir, Michal; Shaish, Aviv; Dissen, Moshe; Shlomai, Gadi; Voronov, Elena; Apte, Ron N; Harats, Dror; Kamari, Yehuda.

Cytokine ; 73(1): 138-43, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25748836

18.

The role of IL-1ß in the early tumor cell-induced angiogenic response.

Carmi, Yaron; Dotan, Shahar; Rider, Peleg; Kaplanov, Irena; White, Malka R; Baron, Rona; Abutbul, Shai; Huszar, Monica; Dinarello, Charles A; Apte, Ron N; Voronov, Elena.

J Immunol ; 190(7): 3500-9, 2013 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-23475218

19.

Non-redundant properties of IL-1α and IL-1ß during acute colon inflammation in mice.

Bersudsky, Marina; Luski, Lotem; Fishman, Daniel; White, Rosalyn M; Ziv-Sokolovskaya, Nadya; Dotan, Shahar; Rider, Peleg; Kaplanov, Irena; Aychek, Tegest; Dinarello, Charles A; Apte, Ron N; Voronov, Elena.

Gut ; 63(4): 598-609, 2014 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23793223

20.

Modification of topoisomerases in mammospheres derived from breast cancer cell line: clinical implications for combined treatments with tyrosine kinase inhibitors.

Peleg, Refael; Romzova, Marianna; Kogan-Zviagin, Inga; Apte, Ron N; Priel, Esther.

BMC Cancer ; 14: 910, 2014 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-25472619

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