[Effect of vitamin A on immunogenesis]. / O vliianii vitamina A na immunogenez.

Experiments made on mice, rats and rabbits have shown that administration of vitamin A promotes an increase in the weight of the lymphoid organs, thymus and spleen and stimulates production of the antibody-forming cells by the spleen, as well as that of serum antibodies during immunization with different antigens: sheep red blood cells, influenza virus, tetanus and staphylococcal toxoids. The possible mechanisms that underlie vitamin A action are discussed.

[Inhibition of the development of adjuvant arthritis in rats as affected by vitamin E]. / Podavlenie razvitiia ad''iuvantnogo artrita u krys pod vliianiem vitamina E.

The experiments on rats have shown that preliminary oral administration of vitamin E significantly suppressed generalization, but not development of adjuvant-induced arthritis. Oral vitamin E administration beginning one day after the onset of arthritis inhibited the development and generalization of the disease. Vitamin E had no effect on serum lysosomal enzyme activity, but markedly depressed lipid peroxidation.

[Immuno-correcting activity of vitamin A in stress]. / Immunokorrigiruiushchee deistvie vitamina A pri stresse.

Experiments on CBA mice have shown that oral vitamin A administration prevents stress-induced immunological disorders: depression of antibody-forming cell production, decrease in natural killer cell activity and T-lymphocyte mitogenic response. Vitamin A also prevents the development of thymus atrophy, lymphopenia and depression of phagocytic activity of peritoneal macrophages.